Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 30123
Validation of a Fluid-Structure Interaction Model of an Aortic Dissection versus a Bench Top Model

Authors: K. Khanafer

Abstract:

The aim of this investigation was to validate the fluid-structure interaction (FSI) model of type B aortic dissection with our experimental results from a bench-top-model. Another objective was to study the relationship between the size of a septectomy that increases the outflow of the false lumen and its effect on the values of the differential of pressure between true lumen and false lumen. FSI analysis based on Galerkin’s formulation was used in this investigation to study flow pattern and hemodynamics within a flexible type B aortic dissection model using boundary conditions from our experimental data. The numerical results of our model were verified against the experimental data for various tear size and location. Thus, CFD tools have a potential role in evaluating different scenarios and aortic dissection configurations.

Keywords: Aortic dissection, fluid-structure interaction, in vitro model, numerical.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1132260

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 538

References:


[1] J. I. Fann, D. C. Miller. “Aortic dissection,” Ann. Vascular Surg., vol. 9, pp. 311-323, 1995.
[2] S. Chung and K. Vafai, “Effect of the fluid-structure interactions on low-density lipoprotein within a multi-layered arterial wall,” J. Biomechanics, vol. 45, pp. 371-381, 2012.
[3] P. Khamdaengyodtai, K. Vafai, P. Sakulchangsatjatai, et al. “Effects of pressure on arterial failure,” J. Biomechanics, vol. 45, pp. 2577-2588, 2012.
[4] S. Chung and K. Vafai, “Low-density lipoprotein transport within a multi-layered arterial wall-effect of the atherosclerotic plaque/stenosis,” J. Biomechanics, vol. 46, pp. 574-585, 2013.
[5] J. J. Ricotta, J. Pagan, M Xenos, et al. “Cardiovascular disease management: the need for better diagnostics,” Med Biol Eng Comput., vol. 46, pp. 1059-1068, 2008.
[6] C. Y. Wen, A. S. Yang, L. Y. Tseng, et al. “Investigation of pulsatile flowfield in healthy thoracic aorta models,” Ann Biomed Eng. vol. 38, pp. 391-402, 2010.
[7] J. Jung, A. Hassanein, R. W. Lyczkowski. „Hemodynamic computation using multiphase flow dynamics in a right coronary artery,” Ann Biomed Eng. vol. 34, pp. 393-407, 2006.
[8] K. M. Tse, P. Chiu, H. P. Lee, et al. “Investigation of hemodyanmics in the development of dissecting aneurysm within patient-specific dissecting aneurismal aortas using computational fluid dynamics (CFD) simulations.” J. Biomech., vol. 44, pp. 827-836, 2010.
[9] Y. Fan, S. W. K. Cheng, K. X. Qing, et al. “Endovascular repair of type B aortic dissection: a study by computational fluid dynamics,” J. Biomedical Science and Engineering, vol. 3, pp. 900-907, 2010.
[10] Z. Cheng, F. P. Tan, C. V. Riga, C. D. Bicknell, M. S. Hamady, R. G. Gibbs, N. B. Wood, and X. Y. Xu, “Analysis of flow patterns in a patient-specific aortic dissection model,” J. Biomech. Eng., vol. 132, pp. 051007-9, 2010.
[11] K. Khanafer and R. Berguer, “Fluid-structure interaction analysis of turbulent pulsatile flow within a layered aortic wall as related to aortic dissection,” J. Biomech., vol. 42, pp. 2642-2648, 2009.
[12] S. Ben Ahmed, D. Dillon-Murphy, C.A. Figueroa. “Computational study of anatomical risk factors in idealized models of type B aortic dissection,” Eur J Vasc Endovasc Surg. vol. 52, pp. 736-745, 2016.
[13] K. Khanafer, M. Schlicht, K. Vafai, S. Prabhakar, and M. Gaith, Validation of a computational model versus a bench top model of an aortic dissection model, Journal of Biomedical Engineering and Informatics, vol. 2, pp. 82-90, 2016.