Comparative Study in Dentinal Tubuli Occlusion Using Bioglass and Copper-Bromide Laser

Authors: Sun Woo Lee, Tae Bum Lee, Yoon Hwa Park, Yoo Jeong Kim

Abstract:

Cervical dentinal hypersensitivity (CDH) affects 8-30% of adults and nearly 85% of perio-treated patients. Various treatment schemes have been applied for treating CDH, among them being fluoride application, laser irradiation, and, recently, bioglass. The purpose of this study was to investigate the influence of bioglass, copper-bromide (Cu-Br) laser irradiation and their combination on dentinal tubule occlusion as a potential dentinal hypersensitivity treatment for CDH. 45 human dentin surfaces were organized into three equal groups: group A received Cu-Br laser only; group B received bioglass only; group C received bioglass followed by Cu-Br laser irradiation. Specimens were evaluated with regard to dentinal tubule occlusion under environmental scanning electron microscope. Treatment modality significantly affected dentinal tubule occlusion (p<0.001). Groups B and C scored higher dentinal tubule occlusion than group A. Binary logistic regression showed that bioglass application significantly (p<0.001) contributed to dentinal tubule occlusion, compared with other variables. Under the conditions used herein and within the limitations of this study, bioglass application, alone or combined with Cu-Br laser irradiation, is a superior method for producing dentinal tubule occlusion, and may lead to an effective treatment modality for CDH.

Keywords: Bioglass, Cu-Br laser, cervical dentinal hypersensitivity, dentinal tubule occlusion.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1339446

References:

[1] Gillam DG, Mordan NJ, Newman HN. The Dentin Disc surface: a plausible model for dentin physiology and dentin sensitivity evaluation. Adv Dent Res. 1997 Nov;11(4):487-501.
[2] Lin PY, Cheng YW, Chu CY, Chien KL, Lin CP, Tu YK. In-office treatment for dentin hypersensitivity: a systematic review and network meta-analysis. J Clin Periodontol. 2013 Jan;40(1):53-64.
[3] Xu BD, Yang PS. The effects of non-surgical periodontal treatment on the formation of root-dentin hypersensitivity. Shanghai Kou Qiang Yi Xue. 2004 Jun;13(3):238-40.
[4] Fischer C, Wennberg A, Fischer RG, Attström R. Clinical evaluation of pulp and dentine sensitivity after supragingival and subgingival scaling. Endod Dent Traumatol. 1991 Dec;7(6):259-65.
[5] Thompson BK, Meyer R, Singh GB, Mitchell W. Desensitization of exposed root surfaces using a semilunar coronally positioned flap. Gen Dent. 2000 Jan-Feb;48(1):68-71.
[6] Gangarosa LP Sr. Current strategies for dentist-applied treatment in the management of hypersensitive dentine. Arch Oral Biol. 1994;39 Suppl:101S-106S.
[7] Yu CH, Chang YC. Clinical efficacy of the Er:YAG laser treatment on hypersensitive dentin. J Formos Med Assoc. 2013 Apr 17.
[8] Moritz A, Schoop U, Goharkhay K, Aoid M, Reichenbach P, Lothaller MA, Wernisch J, Sperr W. Long-term effects of CO2 laser irradiation on treatment of hypersensitive dental necks: results of an in Vivo study. J Clin Laser Med Surg. 1998 Aug;16(4):211-5.
[9] Ladalardo TC, Pinheiro A, Campos RA, Brugnera Júnior A, Zanin F, Albernaz PL, Weckx LL. Laser therapy in the treatment of dentine hypersensitivity. Braz Dent J. 2004;15(2):144-50.
[10] Dilsiz A, Aydin T, Canakci V, Gungormus M. Clinical evaluation of Er:YAG, Nd:YAG, and diode laser therapy for desensitization of teeth with gingival recession. Photomed Laser Surg. 2010 Oct;28 Suppl 2:S11-7.
[11] Birang R, Poursamimi J, Gutknecht N, Lampert F, Mir M. Comparative evaluation of the effects of Nd:YAG and Er:YAG laser in dentin hypersensitivity treatment. Lasers Med Sci. 2007 Mar;22(1):21-4.
[12] Kasai S, Kono T, Yamamoto Y, Kotani H, Sakamoto T, Mito M. Effect of low-power laser irradiation on impulse conduction in anesthetized rabbits. (Department of Surgery, Asahikawa Medical College, Hokkaido, Japan). J Clin Laser Med Surg. 1996 Jun;14(3):107-9.
[13] Birang R, Kaviani N, Mohammadpour M, Abed AM, Gutknecht N, Mir M. Evaluation of Nd:YAG laser on partial oxygen saturation of pulpal blood in anterior hypersensitive teeth. Lasers Med Sci. 2008 Jul;23(3):291-4.
[14] Hong L, Wu M, Zhang C. Using Nd-YAG laser to desensitize the hypersensitive dentine in preparing the abutment teeth for removable partial dentures prosthesis. Zhonghua Kou Qiang Yi Xue Za Zhi. 1997 Jan;32(1):28-30.
[15] McCoy S, Hanna M, Anderson P, McLennan G, Repacholi M. An evaluation of the copper-bromide laser for treating telangiectasia. Dermatol Surg. 1996 Jun;22(6):551-7.
[16] Owen WR, Hoppe E. Copper bromide laser for facial telangiectasia: a dose response evaluation. Australas J Dermatol. 2012 Nov;53(4):281-4.
[17] McCoy SE. Copper bromide laser treatment of facial telangiectasia: results of patients treated over five years. Lasers Surg Med. 1997;21(4):329-40.
[18] Sadick NS, Weiss R. The utilization of a new yellow light laser (578 nm) for the treatment of class I red telangiectasia of the lower extremities. Dermatol Surg. 2002 Jan;28(1):21-5.
[19] Bakry AS, Tamura Y, Otsuki M, Kasugai S, Ohya K, Tagami J. Cytotoxicity of 45S5 bioglass paste used for dentine hypersensitivity treatment. J Dent. 2011 Sep;39(9):599-603.
[20] Kuo TC, Lee BS, Kang SH, Lin FH, Lin CP. Cytotoxicity of DP-bioglass paste used for treatment of dentin hypersensitivity. J Endod. 2007 Apr;33(4):451-4.
[21] Gillam DG, Tang JY, Mordan NJ, Newman HN. The effects of a novel Bioglass dentifrice on dentine sensitivity: a scanning electron microscopy investigation. J Oral Rehabil. 2002 Apr;29(4):305-13.
[22] Bakry AS, Takahashi H, Otsuki M, Tagami J. The durability of phosphoric acid promoted bioglass-dentin interaction layer. Dent Mater. 2013 Apr;29(4):357-64.
[23] Farmakis ET, Kozyrakis K, Khabbaz MG, Schoop U, Beer F, Moritz A. In vitro evaluation of dentin tubule occlusion by Denshield and Neodymium-doped yttrium-aluminum-garnet laser irradiation. J Endod. 2012 May;38(5):662-6.
[24] Lee BS, Chang CW, Chen WP, Lan WH, Lin CP. In vitro study of dentin hypersensitivity treated by Nd:YAP laser and bioglass. Dent Mater. 2005 Jun;21(6):511-9.
[25] Tung MS, Bowen HJ, Derkson GD, Pashley DH. Effects of calcium phosphate solutions on dentin permeability. J Endod. 1993 Aug;19(8):383-7.
[26] Pesun IJ, Hodges J, Lai JH. Effect of finishing and polishing procedures on the gap width between a denture base resin and two long-term, resilient denture liners. J Prosthet Dent. 2002 Mar;87(3):311-8.
[27] Chiang YC, Chen HJ, Liu HC, Kang SH, Lee BS, Lin FH, Lin HP, Lin CP. A novel mesoporous biomaterial for treating dentin hypersensitivity. J Dent Res. 2010 Mar;89(3):236-40.
[28] Yu Xq, An Yb, Luan Qx. Effects of bio-glass in subgingival scaling and root planing. Beijing Da Xue Xue Bao. 2011 Feb 18;43(1):40-3.
[29] Curtis AR, West NX, Su B. Synthesis of nanobioglass and formation of apatite rods to occlude exposed dentine tubules and eliminate hypersensitivity. Acta Biomater. 2010 Sep;6(9):3740-6.
[30] Lee BS, Kang SH, Wang YL, Lin FH, Lin CP. In vitro study of dentinal tubule occlusion with sol-gel DP-bioglass for treatment of dentin hypersensitivity. Dent Mater J. 2007 Jan;26(1):52-61.
[31] Farmakis ET, Beer F, Kozyrakis K, Pantazis N, Moritz A. The influence of different power settings of Nd:YAG laser irradiation, bioglass and combination to the occlusion of dentinal tubules. Photomed Laser Surg. 2013 Feb;31(2):54-8.
[32] Narongdej T, Sakoolnamarka R, Boonroung T. The effectiveness of a calcium sodium phosphosilicate desensitizer in reducing cervical dentin hypersensitivity: a pilot study. J Am Dent Assoc. 2010 Aug;141(8):995-9.