Commenced in January 2007
Paper Count: 30302
Nonlinear Analysis of Postural Sway in Multiple Sclerosis
Abstract:Multiple Sclerosis (MS) is a disease which affects the central nervous system and causes balance problem. In clinical, this disorder is usually evaluated using static posturography. Some linear or nonlinear measures, extracted from the posturographic data (i.e. center of pressure, COP) recorded during a balance test, has been used to analyze postural control of MS patients. In this study, the trend (TREND) and the sample entropy (SampEn), two nonlinear parameters were chosen to investigate their relationships with the expanded disability status scale (EDSS) score. 40 volunteers with different EDSS scores participated in our experiments with eyes open (EO) and closed (EC). TREND and 2 types of SampEn (SampEn1 and SampEn2) were calculated for each combined COP’s position signal. The results have shown that TREND had a weak negative correlation to EDSS while SampEn2 had a strong positive correlation to EDSS. Compared to TREND and SampEn1, SampEn2 showed a better significant correlation to EDSS and an ability to discriminate the MS patients in the EC case. In addition, the outcome of the study suggests that the multi-dimensional nonlinear analysis could provide some information about the impact of disability progression in MS on dynamics of the COP data.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1110834Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1592
 J. F. Kurtzke, “Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS),” Neurology., vol. 33, pp. 1444- 1452, 1983.
 A. Yahia, S. Ghroubi, C. Mhiri, and M. H. Elleuch, “Relationship between muscular strength, gait and postural parameters in multiple sclerosis,” Ann. Phys. Rehabil. Med., vol. 54, pp. 144-155, 2011.
 A. Porosinska, K. Pierzchala, M. Mentel, and J. Karpe, “Evaluation of postural balance control in patients with multiple sclerosis – effect of different sensory conditions and arithmetic task execution. A pilot study,” Neurol. Neurochir. Pol., vol. 44, pp. 35–42, 2010.
 L. Peyrodie, S. Boudet, A. Pinti, F. Cavillon, O. Agnani, and P. Gallois, “Relations entre posturologie et score EDSS,” Sciences et Technologies pour le Handicap, vol. 4, pp. 55-71, 2010.
 H. Cao, L. Peyrodie, S. Boudet, F. Cavillon, O. Agnani, P. Hautecoeur, and C. Donzé, “Expanded Disability Status Scale (EDSS) estimation in multiple sclerosis from posturographic data,” Gait Posture, vol. 37, pp. 242-245, 2013.
 J. M. Huisinga, J. M. Yentes, M. L. Filipi, and N. Stergiou, “Postural control strategy during standing is altered in patients with multiple sclerosis,” Neurosci Lett., vol. 524, pp. 124-128, 2012.
 H. Negahban, M. A. Sanjari, R. Mofateh, and M. Parnianpour, “Nonlinear dynamical structure of sway path during standing in patients with multiple sclerosis and in healthy controls is affected by changes in sensory input and cognitive load,” Neurosci Lett., vol. 553, pp.126-131, 2013.
 N. Marwan, M. Carmenromano, M. Thiel, and J. Kurths, “Recurrence plots for the analysis of complex systems,” Physics Reports, vol. 438, pp. 237-329, 2007.
 S. Ramdani, G. Tallon, P. L. Bernard, and H. Blain, “Recurrence Quantification Analysis of Human Postural Fluctuations in Older Fallers and Non-fallers,” Annals of Biomedical Engineering, vol. 41, pp. 1713- 1725, 2013.
 S. Ramdani, B. Seigle, J. Lagarde, F. Bouchara, and P. L. Bernard, “On the use of sample entropy to analyze human postural sway data,” Med Eng Phys., vol. 31, pp. 1023-1031, 2009.
 C. K. Rhea, T. A. Silver, S. L. Hong, J. H. Ryu, B. E. Studenka, C. M. Hughes, and J. M. Haddad, “Noise and Complexity in Human Postural Control: Interpreting the Different Estimations of Entropy”, PLoS One, vol. 6, pp. e17696, 2011.
 M. Aboy, D. Cuesta-Frau, D. Austin, and P. Mico-Tormos, “Characterization of Sample Entropy in the Context of Biomedical Signal Analysis,” in Proc. 29th Annu. Int. Conf. IEEE EMBS, Lyon, 2007, pp. 5942–5945.
 M. Mazaheri, M. Salavati, H. Negahban, M. A. Sanjari, and M. Parnianpour, “Postural sway in low back pain: Effects of dual tasks,” Gait Posture, vol. 31, pp. 116-121, 2010.
 J. M. Schmit, M. A. Riley, A. Dalvi, A. Sahay, P. K. Shear, K. D. Shockley, and R. Y. Pun, “Deterministic center of pressure patterns characterize postural instability in Parkinson's disease,” Exp Brain Res., vol. 168, pp. 357-367, 2006.
 S. F. Donker, M. Roerdink, A. J. Greven, and P. J. Beek, “Regularity of center-of-pressure trajectories depends on the amount of attention invested in postural control,” Exp Brain Res., vol. 181, pp. 1-11, 2007.