Dengue Death Review: A Tool to Adjudge the Cause of Dengue Mortality and Use of the Tool for Prevention of Dengue Deaths

Authors: Gagandeep Singh Grover, Vini Mahajan, Bhagmal, Priti Thaware, Jaspreet Takkar

Abstract:

Dengue is a mosquito-borne viral disease endemic in many countries in the tropics and sub-tropics. The state of Punjab in India shows cyclical and seasonal variation in dengue cases. The Case Fatality Rate of Dengue has ranged from 0.6 to 1.0 in the past years. The department has initiated review of the cases that have died due to dengue in order to know the exact cause of the death in a case of dengue. The study has been undertaken to know the other associated co-morbidities and factors causing death in a case of dengue. The study used the predesigned proforma on which the records (medical and Lab) were recorded and reviewed by the expert committee of the doctors. This study has revealed that cases of dengue having co-morbidities have longer stay in hospital. Fluid overload and co-morbidities have been found as major factors leading to death, however, in a confirmed case of dengue hepatorenal shutdown was found to be major cause of mortality. The data obtained will help in sensitizing the treating physicians in order to decrease the mortality due to dengue in future.

Keywords: Dengue, death, morbidities, DHF, DSS.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1110574

References:

[1] World Health Organization (WHO) and the Special Programme for Research and Training in Tropical Diseases (TDR): Dengue: guidelines for diagnosis, treatment, prevention and control Geneva: WHO; 2009, New Edition.
[2] Ooi EE, Goh KT, Gubler DJ: Dengue prevention and 35 years of vector control in Singapore. Emerg Infect Dis 2006, 12(6):887-893.
[3] World Health Organization (WHO): Dengue Haemorrhagic Fever: Diagnosis,Treatment, Prevention and Control. 2 edition. Geneva: WHO; 1997.
[4] Bandyopadhyay S, Lum LC, Kroeger A: Classifying dengue: a review of thedifficulties in using the WHO case classification for dengue haemorrhagic fever. Trop Med Int Health 2006, 11(8):1238-1255.
[5] National Guidelines for Clinical Management of Dengue Fever. National Vector Borne Disease Control Programme, Govt. of India: 2014.
[6] World Health Organization (WHO): Handbook for clinical management of dengue. 2012.
[7] World Health Organization (WHO): Dengue/ Dengue Haemorrhagic Fever. Prevention and Control.SEA-Haem.Fev-75, 2002.
[8] World Health Organization (WHO): Guidelines for treatment of Dengue and Dengue Haemorrhagic Fever in small Hospitals. ROF-SEA, 1999.
[9] World Health Organization (WHO): Comprehensive Guidelines for Prevention and Control of Dengue and DHF. Revised and Expanded edition. 2011.
[10] Clinical Practice Guidelines. Management of Dengue Infection in Adults. MOH/PAK/209.10 (GU).
[11] Guidelines for Clinical Management of Dengue Fever, Dengue Haemorrhagic Fever and Dengue Shock Syndrome. Department of National Vector Borne Disease Control Programme, Directorate of Health Services, Govt. of India. 2008.
[12] World Health Organization (WHO): Prevention and Control of Dengue and DHF. Comprehensive Guidelines. WHO Regional Publication, SEARO No. 29. 1995.
[13] CDC: Dengue and Dengue Haemorrhagic Fever. Information for Healthcare Practitioners. US Department of Health and Human Services. Centre for Disease Cntrol and Prevention.