Commenced in January 2007
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The Application of FSI Techniques in Modeling of Realist Pulmonary Systems

Authors: Abdurrahim Bolukbasi, Dogan Ciloglu, Hassan Athari

Abstract:

The modeling lung respiratory system that has complex anatomy and biophysics presents several challenges including tissue-driven flow patterns and wall motion. Also, the pulmonary lung system because of that they stretch and recoil with each breath, has not static walls and structures. The direct relationship between air flow and tissue motion in the lung structures naturally prefers an FSI simulation technique. Therefore, in order to toward the realistic simulation of pulmonary breathing mechanics the development of a coupled FSI computational model is an important step. A simple but physiologically relevant three-dimensional deep long geometry is designed and fluid-structure interaction (FSI) coupling technique is utilized for simulating the deformation of the lung parenchyma tissue that produces airflow fields. The real understanding of respiratory tissue system as a complex phenomenon have been investigated with respect to respiratory patterns, fluid dynamics and tissue viscoelasticity and tidal breathing period. 

Keywords: Fluid-structure interactions, Viscoelasticity, Tissue Mechanics, ANSYS, lung deformation and mechanics

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1107377

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References:


[1] L.B. Ware, M.A. Matthay, “The acute respiratory distress syndrome,” New Eng J Med 2000 vol.18, pp.1334–49.
[2] J.D. Ricard, D. Dreyfuss and G. Saumon. “Ventilator-induced lung injury,” Eur Respir 2003 vol.22, pp.42-48.
[3] A.M. Jacob and D.P. Gaver, “An investigation of the influence of cell topography on epithelial mechanical stresses during pulmonary airway reopening,” Phys Fluids 2005 vol.17, pp. 315-322.
[4] M.G. Levitzky. “Pulmonary physiology,” New York: McGraw-Hill 1991.
[5] C. Darquenne, “A realistic two-dimensional model of aerosol transport and deposition in the alveolar zone of the human lung,” Journal of Aerosol Science, 32, pp. 1161–1174, 2001.
[6] C. Darquenne and G.K. Prisk, “Effect of gravitational sedimentation on simulated aerosol dispersion in the human acinus,” Journal of Aerosol Science 2002 vol. 34, pp. 405–418.
[7] S. Haber, J.P. Butler, H. Brenner, I. Emanuel and A. Tsuda, “Shear flow over a self-similar expanding pulmonary alveolus during rhythmical breathing,” Journal of Fluid Mechanics 2000 vol. 405, pp. 243–268.
[8] F.S. Henry, J.P. Butler and A. Tsuda, “Kinematically irreversible acinar flow: a departure from classical dispersive aerosol transport theories,” Journal of Applied Physiology 2002 vol. 92, pp. 835–845.
[9] A. Tsuda, J.P. Butler and J.J. Fredberg, “Effects of alveolated duct structure on aerosol kinetics I. Diffusional deposition in the absence of gravity,” Journal of Applied Physiology 1994 vol. 76, pp. 2497–2509.
[10] F.G. Hoppin, J.C. Stothert, I.A. Greaves, Y-L. Lai and J. Hildebrandt, “Lung recoil: elastic and rheological properties,” In: A. Fishman, P. T. Macklem, J. Mead, & S. R. Geiger (Eds.), Handbook of physiology, III, mechanics of breathing, part 1 1986 pp. 195–215.
[11] K-J. Bathe, H. Zhang and S. Ji, “Finite element analysis of fluid flows fully coupled with structural interactions,” Comput Struct 1999 vol. 72, pp. 1–16.
[12] K-J. Bathe and H. Zhang, “Finite element developments for general flows with structural interactions,” Int J Numer Met Eng 2004 vol. 60, pp. 213–32.
[13] L. Harrington, G. Kim Prisk and C. Darquenne, “Importance of the bifurcation zone and branch orientation in simulated aerosol deposition in the alveolar zone of the human lung,” J Aerosol Sci 2006 vol. 37, pp.37–62.