Correlation of Structure and Antiviral Activity of Alkaloids of Polygonum L. Plants Growing in Kazakhstan
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Correlation of Structure and Antiviral Activity of Alkaloids of Polygonum L. Plants Growing in Kazakhstan

Authors: Dmitriy Yu. Korulkin, Raissa A. Muzychkina

Abstract:

The article represents the results of isolation and component chromatographic analysis of essential oils of Polygonym L. plants growing in Kazakhstan in commercial reserves at the territory of Kazakhstan. The results of research of antiviral activity of isolated substances to flu virus have been represented in this article. The main pharmacophore groups in the structure of alkaloids have been identified.

Keywords: Alkaloids, antiviral, bioactive substances, isolation, pharmacophore groups, Polygonum L.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1106739

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References:


[1] P. M. Dewick, Medicinal Natural Products, N.-Y.: John Wiley & Sons Ltd, 2002.
[2] M. Heinrich, J. Barnes, S. Gibbons, Fundamentals of Pharmacognosy and Phytotherapy, N.-Y.: Elsevier, 2012.
[3] M. Wichtl, Herbal drugs and phytopharmaceuticals, Stuttgart: CRC Press, 2007.
[4] B. Ozcelik, M. Aslan, I. Orhan, T. Karaoglu, Microbiol. Res., vol. 160, pp. 159-164, 2005.
[5] B. S. Min, Y. H. Kim, M. Tomiyama, N. Nakamura, Phytother. Res., vol. 15, pp. 481-486, 2001.
[6] R. A. Muzychkina, D. Yu. Korulkin, Bioactive constituents of plants. Extraction, separation and analysis, Almaty: Atamura, 2006.
[7] R. A. Muzychkina, D. Yu. Korulkin, Methodology of research of natural metabolites, Almaty: MV-Print, 2012.
[8] L. Kursinszki, H. Hank, I. Laszlo, J. Chromatogr. A, vol. 1091, pp. 32– 39, 2005.
[9] Н. Balfour, M. E. M. Benwell, P. E. Holtom, New Engl. J. of Med., vol. 340, no. 16, pp. 1255-1268, 1999.
[10] E. Clerco, M. Vandewalle, J. Pharmacol. Exper. Therap., vol. 297, no. 1, pp. 1-10, 2000.
[11] J. M. Hu, G. D. Hsiung, Antiviral. Res., vol. 11, no. 5-6, pp. 217-232, 1989.
[12] E. Fattorusso, O. Taglialatela-Scafati, Modern Alkaloids: Structure, Isolation, Synthesis and Biology, Weinheim: Wiley-VCH, 2008..
[13] L. J. Cseke, A. Kirakosyan, P. B. Kaufman, Natural Products from Plants, London: CRC Press, 2006.
[14] J. Dai, R. J. Mumper, P. E. Larsen, J. C. Zwick, Molecules, vol. 15, pp.7313-7352, 2010.
[15] K. M. Marshalla, S. S. Matsumotoa, J . A. Holdenb, Biochem. Pharmacol., vol. 66, pp. 447-462, 2003.
[16] A. Stepanchikova, A. Lagunin, D . Filimonov, V. Poroikov, Current Med. Chem., vol.10, pp. 225-232, 2003.