Improving the Optoacoustic Signal by Monitoring the Changes of Coupling Medium
In this paper, we discussed the coupling medium in the optoacoustic imaging. The coupling medium is placed between the scanned object and the ultrasound transducers. Water with varying temperature was used as the coupling medium. The water temperature is gradually varied between 25 to 40 degrees. This heating process is taken with care in order to avoid the bubble formation. Rise in the photoacoustic signal is noted through an unfocused transducer with frequency of 2.25 MHz as the temperature increases. The temperature rise is monitored using a NTC thermistor and the values in degrees are calculated using an embedded evaluation kit. Also the temperature is transmitted to PC through a serial communication. All these processes are synchronized using a trigger signal from the laser source.
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 A. A. Oraevsky, S. L. Jacques, R. O. Esenaliev, and F. K. Tittel, “Laser based optoacoustic imaging in biological tissues,” Proc. SPIE 2134A, 122–128 1994.
 C. G. A. Hoelen, F. F. M. de Mul, R. Pongers, and A. Dekker, “Threedimensional photoacoustic imaging of blood vessels in tissue,” Opt. Lett. 23, 648–650 1998.
 Palaniappan, P., Shin, A.H. and Song, C.G., 2016. Image Enhancement Using Active Contour Filtering Methods for a Custom-Developed Real-Time Photoacoustic Tomography System to Accurately Delineate a Target. Journal of Medical Imaging and Health Informatics, 6(7), pp.1696-1700.
 Monici, Monica; El-Gewely, MR. Biotechnology Annual Review. Vol. volume 11. Elsevier; 2005. Cell and tissue autofluorescence research and diagnostic applications; p. 227-256.
 Zhang H F, Maslov K, Stoica G, Wang L-H, Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging, Nat. Biotechnol. 24 848.51, 2006.
 X. Wang, D. L. Chamberland, and D. A. Jamadar, Noninvasive photoacoustic tomography of human peripheral joints toward diagnosis of inflammatory arthritis, Opt. Lett., Vol. 32, No. 20, p. 3002-3004, Oct. 2007.
 S. Manohar, A. Kharine, J. C. van Hespen, W. Steenbergen, and T. G. van Leeuwen, The Twente Photoacoustic Mammoscope: system overview and performance, Phys. Med. Biol., Vol. 50, No. 11, p. 2543-2557, Jun. 2005.
 S. Yang, D. Xing, Q. Zhou, L. Xiang, and Y. Lao, Functional imaging of cerebrovascular activities in small animals using high-resolution photoacoustic tomography, Med. Phys., Vol. 34, No. 8, p. 3294-3301, Aug. 2007.
 Lin, L., Xia, J., Wong, T.T., Li, L. and Wang, L.V., 2015. In vivo deep brain imaging of rats using oral-cavity illuminated photoacoustic computed tomography. Journal of biomedical optics, 20(1), pp.016019-016019.
 Wang K, Ermilov S, Su R, Brecht H, Oraevsky A, et al. (2011) An Imaging Model Incorporating Ultrasonic Transducer Properties for Three-Dimensional Optoacoustic Tomography. Medical Imaging, IEEE Transactions on 203–214.
 Yin B, Xing D, Wang Y, Zeng Y, Tan Y, et al. (2004) Fast photoacoustic imaging system based on 320-element linear transducer array. Physics in medicine and biology 49: 1339.
 Kruger R, Lam R, Reinecke D, Del Rio S, Doyle R, et al. (2010) Photoacoustic angiography of the breast. Med Phys 37: 6096–6100.
 Zhang E, Laufer J, Beard P (2008) Backward-mode multiwavelength photoacoustic scanner using a planar fabry-perot polymer film ultrasound sensor for high-resolution three-dimensional imaging of biological tissues. Applied optics 47: 561–577.
 Gamelin J, Aguirre A, Maurudis A, Huang F, Castillo D, et al. (2008) Curved array photoacoustic tomographic system for small animal imaging. Journal of biomedical optics 13: 024007.
 Xu MH, Wang LHV. Photoacoustic imaging in biomedicine. Review of Scientific Instruments 2006;77(4).
 Duck, FA. Physical Properties of Tissue. London: Academic; 1990.
 Diebold GJ, Sun T, Khan MI. Phtoacoustic monopole radiation in 1-dimention, 2-dimension, and 3- dimension. Physical Review Letters 1991;67(24):3384–3387.
 Morse, Philip M.; Uno Ingard, K. Theoretical Acoustics. Princeton, New Jersey: Princeton University Press; 1986.
 Li, C., Pramanik, M., Ku, G., & Wang, L. V. (2008). Image distortion in thermoacoustic tomography caused by microwave diffraction. Physical Review E, 77(3), 031923.
 Wang, L. V. (2008). Tutorial on photoacoustic microscopy and computed tomography. IEEE Journal of Selected Topics in Quantum Electronics, 14(1), 171-179.
 Van de Sompel, Dominique, Laura Sarah Sasportas, Anca Dragulescu-Andrasi, Sarah Bohndiek, and Sanjiv Sam Gambhir. "Improving image quality by accounting for changes in water temperature during a photoacoustic tomography scan." PloS one 7, no. 10 (2012): e45337.
 M. Xu and L. V. Wang, Universal back-projection algorithm for photoacoustic-computed tomography, Physical Review E71, 2005.