Search results for: entropy and information in fractalnetworks of oxidative activity of DNA
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 5222

Search results for: entropy and information in fractalnetworks of oxidative activity of DNA

5222 Shannon-Weaver Biodiversity of Neutrophils in Fractal Networks of Immunofluorescence for Medical Diagnostics

Authors: N.E.Galich

Abstract:

We develop new nonlinear methods of immunofluorescence analysis for a sensitive technology of respiratory burst reaction of DNA fluorescence due to oxidative activity in the peripheral blood neutrophils. Histograms in flow cytometry experiments represent a fluorescence flashes frequency as functions of fluorescence intensity. We used the Shannon-Weaver index for definition of neutrophils- biodiversity and Hurst index for definition of fractal-s correlations in immunofluorescence for different donors, as the basic quantitative criteria for medical diagnostics of health status. We analyze frequencies of flashes, information, Shannon entropies and their fractals in immunofluorescence networks due to reduction of histogram range. We found the number of simplest universal correlations for biodiversity, information and Hurst index in diagnostics and classification of pathologies for wide spectra of diseases. In addition is determined the clear criterion of a common immunity and human health status in a form of yes/no answers type. These answers based on peculiarities of information in immunofluorescence networks and biodiversity of neutrophils. Experimental data analysis has shown the existence of homeostasis for information entropy in oxidative activity of DNA in neutrophil nuclei for all donors.

Keywords: blood and cells fluorescence in diagnostics ofdiseases, cytometric histograms, entropy and information in fractalnetworks of oxidative activity of DNA, long-range chromosomalcorrelations in living cells.

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5221 Information Theoretical Analysis of Neural Spiking Activity with Temperature Modulation

Authors: Young-Seok Choi

Abstract:

This work assesses the cortical and the sub-cortical neural activity recorded from rodents using entropy and mutual information based approaches to study how hypothermia affects neural activity. By applying the multi-scale entropy and Shannon entropy, we quantify the degree of the regularity embedded in the cortical and sub-cortical neurons and characterize the dependency of entropy of these regions on temperature. We study also the degree of the mutual information on thalamocortical pathway depending on temperature. The latter is most likely an indicator of coupling between these highly connected structures in response to temperature manipulation leading to arousal after global cerebral ischemia.

Keywords: Spiking activity, entropy, mutual information, temperature modulation.

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5220 Assessing Complexity of Neuronal Multiunit Activity by Information Theoretic Measure

Authors: Young-Seok Choi

Abstract:

This paper provides a quantitative measure of the time-varying multiunit neuronal spiking activity using an entropy based approach. To verify the status embedded in the neuronal activity of a population of neurons, the discrete wavelet transform (DWT) is used to isolate the inherent spiking activity of MUA. Due to the de-correlating property of DWT, the spiking activity would be preserved while reducing the non-spiking component. By evaluating the entropy of the wavelet coefficients of the de-noised MUA, a multiresolution Shannon entropy (MRSE) of the MUA signal is developed. The proposed entropy was tested in the analysis of both simulated noisy MUA and actual MUA recorded from cortex in rodent model. Simulation and experimental results demonstrate that the dynamics of a population can be quantified by using the proposed entropy.

Keywords: Discrete wavelet transform, Entropy, Multiresolution, Multiunit activity.

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5219 Normalization and Constrained Optimization of Measures of Fuzzy Entropy

Authors: K.C. Deshmukh, P.G. Khot, Nikhil

Abstract:

In the literature of information theory, there is necessity for comparing the different measures of fuzzy entropy and this consequently, gives rise to the need for normalizing measures of fuzzy entropy. In this paper, we have discussed this need and hence developed some normalized measures of fuzzy entropy. It is also desirable to maximize entropy and to minimize directed divergence or distance. Keeping in mind this idea, we have explained the method of optimizing different measures of fuzzy entropy.

Keywords: Fuzzy set, Uncertainty, Fuzzy entropy, Normalization, Membership function

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5218 Information Entropy of Isospectral Hydrogen Atom

Authors: Anil Kumar, C. Nagaraja Kumar

Abstract:

The position and momentum space information entropies of hydrogen atom are exactly evaluated. Using isospectral Hamiltonian approach, a family of isospectral potentials is constructed having same energy eigenvalues as that of the original potential. The information entropy content is obtained in position space as well as in momentum space. It is shown that the information entropy content in each level can be re-arranged as a function of deformation parameter.

Keywords: Information Entropy, BBM inequality, Isospectral Potential.

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5217 On Generalized Exponential Fuzzy Entropy

Authors: Rajkumar Verma, Bhu Dev Sharma

Abstract:

In the present communication, the existing measures of fuzzy entropy are reviewed. A generalized parametric exponential fuzzy entropy is defined.Our study of the four essential and some other properties of the proposed measure, clearly establishes the validity of the measure as an entropy.

Keywords: fuzzy sets, fuzzy entropy, exponential entropy, exponential fuzzy entropy.

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5216 The Oxidative Damage Marker for Sodium Formate Exposure on Lymphocytes

Authors: Malinee Pongsavee

Abstract:

Sodium formate is the chemical substance used for food additive. Catalase is the important antioxidative enzyme in protecting the cell from oxidative damage by reactive oxygen species (ROS). The resultant level of oxidative stress in sodium formatetreated lymphocytes was investigated. The sodium formate concentrations of 0.05, 0.1, 0.2, 0.4 and 0.6 mg/mL were treated in human lymphocytes for 12 hours. After 12 treated hours, catalase activity change was measured in sodium formate-treated lymphocytes. The results showed that the sodium formate concentrations of 0.4 and 0.6 mg/mL significantly decreased catalase activities in lymphocytes (P < 0.05). The change of catalase activity in sodium formate-treated lymphocytes may be the oxidative damage marker for detect sodium formate exposure in human.

Keywords: Sodium formate, catalase activity, oxidative damage marker, toxicity.

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5215 Extending the Quantum Entropy to Multidimensional Signal Processing

Authors: Youssef Khmou, Said Safi, Miloud Frikel

Abstract:

This paper treats different aspects of entropy measure in classical information theory and statistical quantum mechanics, it presents the possibility of extending the definition of Von Neumann entropy to image and array processing. In the first part, we generalize the quantum entropy using singular values of arbitrary rectangular matrices to measure the randomness and the quality of denoising operation, this new definition of entropy can be implemented to compare the performance analysis of filtering methods. In the second part, we apply the concept of pure state in quantum formalism to generalize the maximum entropy method for narrowband and farfield source localization problem. Several computer simulation results are illustrated to demonstrate the effectiveness of the proposed techniques.

Keywords: Von Neumann entropy, Filtering, array, DoA, Maximum Entropy Method.

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5214 Effects of Ciprofloxacin and Levofloxacin Administration on Some Oxidative Stress Markers in the Rat

Authors: Olusegun K. Afolabi, Emmanuel B. Oyewo

Abstract:

Fluoroquinolones are a group of antibiotics widely used because of their broad spectrum activity against both Gram-positive and Gram-negative bacteria. In this study, ciprofloxacin and levofloxacin were administered to rats at therapeutic doses to evaluate their effects on plasma arylesterase activity, as well as, on hepatic advanced oxidized protein products (AOPPs) and malondialdehyde (MDA) levels, as measures of oxidative stress. Ciprofloxacin (80 mg/kg body weight) and levofloxacin (40 mg/kg body weight) were administered to male albino rats for 7 and 14 days. The data obtained demonstrated that plasma arylesterase activity was significantly decreased by both drugs with ciprofloxacin administration inhibiting the activity by 29% and 30% while Levofloxacin treatment resulted in 35% and 30% inhibition, after 7 and 14 days treatment respectively. Hepatic AOPP and MDA levels were both elevated by these antibiotics. This study supplies further evidence that fluoroquinolones at therapeutic doses promote oxidative stress.

Keywords: Arylesterase, Ciprofloxacin, Levofloxacin, Oxidative Stress.

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5213 Entropy Measures on Neutrosophic Soft Sets and Its Application in Multi Attribute Decision Making

Authors: I. Arockiarani

Abstract:

The focus of the paper is to furnish the entropy measure for a neutrosophic set and neutrosophic soft set which is a measure of uncertainty and it permeates discourse and system. Various characterization of entropy measures are derived. Further we exemplify this concept by applying entropy in various real time decision making problems.

Keywords: Entropy measure, Hausdorff distance, neutrosophic set, soft set.

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5212 Entropy Analysis in a Bubble Column Based on Ultrafast X-Ray Tomography Data

Authors: Stoyan Nedeltchev, Markus Schubert

Abstract:

By means of the ultrafast X-ray tomography facility, data were obtained at different superficial gas velocities UG in a bubble column (0.1 m in ID) operated with an air-deionized water system at ambient conditions. Raw reconstructed images were treated by both the information entropy (IE) and the reconstruction entropy (RE) algorithms in order to identify the main transition velocities in a bubble column. The IE values exhibited two well-pronounced minima at UG=0.025 m/s and UG=0.085 m/s identifying the boundaries of the homogeneous, transition and heterogeneous regimes. The RE extracted from the central region of the column’s cross-section exhibited only one characteristic peak at UG=0.03 m/s, which was attributed to the transition from the homogeneous to the heterogeneous flow regime. This result implies that the transition regime is non-existent in the core of the column.

Keywords: Bubble column, ultrafast X-ray tomography, information entropy, reconstruction entropy.

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5211 Complexity of Multivalued Maps

Authors: David Sherwell, Vivien Visaya

Abstract:

We consider the topological entropy of maps that in general, cannot be described by one-dimensional dynamics. In particular, we show that for a multivalued map F generated by singlevalued maps, the topological entropy of any of the single-value map bounds the topological entropy of F from below.

Keywords: Multivalued maps, Topological entropy, Selectors

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5210 Assessment of Multiscale Information for Short Physiological Time Series

Authors: Young-Seok Choi

Abstract:

This paper presents a multiscale information measure of Electroencephalogram (EEG) for analysis with a short data length. A multiscale extension of permutation entropy (MPE) is capable of fully reflecting the dynamical characteristics of EEG across different temporal scales. However, MPE yields an imprecise estimation due to coarse-grained procedure at large scales. We present an improved MPE measure to estimate entropy more accurately with a short time series. By computing entropies of all coarse-grained time series and averaging those at each scale, it leads to the modified MPE (MMPE) which provides an enhanced accuracy as compared to MPE. Simulation and experimental studies confirmed that MMPE has proved its capability over MPE in terms of accuracy.

Keywords: Multiscale entropy, permutation entropy, EEG, seizure.

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5209 Identification of the Main Transition Velocities in a Bubble Column Based on a Modified Shannon Entropy

Authors: Stoyan Nedeltchev, Markus Schubert

Abstract:

The gas holdup fluctuations in a bubble column (0.15 m in ID) have been recorded by means of a conductivity wire-mesh sensor in order to extract information about the main transition velocities. These parameters are very important for bubble column design, operation and scale-up. For this purpose, the classical definition of the Shannon entropy was modified and used to identify both the onset (at UG=0.034 m/s) of the transition flow regime and the beginning (at UG=0.089 m/s) of the churn-turbulent flow regime. The results were compared with the Kolmogorov entropy (KE) results. A slight discrepancy was found, namely the transition velocities identified by means of the KE were shifted to somewhat higher (0.045 and 0.101 m/s) superficial gas velocities UG.

Keywords: Bubble column, gas holdup fluctuations, Modified Shannon entropy, Kolmogorov entropy.

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5208 Reasons for Non-Applicability of Software Entropy Metrics for Bug Prediction in Android

Authors: Arvinder Kaur, Deepti Chopra

Abstract:

Software Entropy Metrics for bug prediction have been validated on various software systems by different researchers. In our previous research, we have validated that Software Entropy Metrics calculated for Mozilla subsystem’s predict the future bugs reasonably well. In this study, the Software Entropy metrics are calculated for a subsystem of Android and it is noticed that these metrics are not suitable for bug prediction. The results are compared with a subsystem of Mozilla and a comparison is made between the two software systems to determine the reasons why Software Entropy metrics are not applicable for Android.

Keywords: Android, bug prediction, mining software repositories, Software Entropy.

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5207 Analysis of EEG Signals Using Wavelet Entropy and Approximate Entropy: A Case Study on Depression Patients

Authors: Subha D. Puthankattil, Paul K. Joseph

Abstract:

Analyzing brain signals of the patients suffering from the state of depression may lead to interesting observations in the signal parameters that is quite different from a normal control. The present study adopts two different methods: Time frequency domain and nonlinear method for the analysis of EEG signals acquired from depression patients and age and sex matched normal controls. The time frequency domain analysis is realized using wavelet entropy and approximate entropy is employed for the nonlinear method of analysis. The ability of the signal processing technique and the nonlinear method in differentiating the physiological aspects of the brain state are revealed using Wavelet entropy and Approximate entropy.

Keywords: EEG, Depression, Wavelet entropy, Approximate entropy, Relative Wavelet energy, Multiresolution decomposition.

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5206 Mean Codeword Lengths and Their Correspondence with Entropy Measures

Authors: R.K.Tuli

Abstract:

The objective of the present communication is to develop new genuine exponentiated mean codeword lengths and to study deeply the problem of correspondence between well known measures of entropy and mean codeword lengths. With the help of some standard measures of entropy, we have illustrated such a correspondence. In literature, we usually come across many inequalities which are frequently used in information theory. Keeping this idea in mind, we have developed such inequalities via coding theory approach.

Keywords: Codeword, Code alphabet, Uniquely decipherablecode, Mean codeword length, Uncertainty, Noiseless channel

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5205 Codes and Formulation of Appropriate Constraints via Entropy Measures

Authors: R. K. Tuli

Abstract:

In present communication, we have developed the suitable constraints for the given the mean codeword length and the measures of entropy. This development has proved that Renyi-s entropy gives the minimum value of the log of the harmonic mean and the log of power mean. We have also developed an important relation between best 1:1 code and the uniquely decipherable code by using different measures of entropy.

Keywords: Codeword, Instantaneous code, Prefix code, Uniquely decipherable code, Best one-one code, Mean codewordlength

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5204 Entropy Generation for Natural Convection in a Darcy – Brinkman Porous Cavity

Authors: Ali Mchirgui, Nejib Hidouri, Mourad Magherbi, Ammar Ben Brahim

Abstract:

The paper provides a numerical investigation of the entropy generation analysis due to natural convection in an inclined square porous cavity. The coupled equations of mass, momentum, energy and species conservation are solved using the Control Volume Finite-Element Method. Effect of medium permeability and inclination angle on entropy generation is analysed. It was found that according to the Darcy number and the porous thermal Raleigh number values, the entropy generation could be mainly due to heat transfer or to fluid friction irreversibility and that entropy generation reaches extremum values for specific inclination angles.

Keywords: Porous media, entropy generation, convection, numerical method.

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5203 Changes to Oxidative Stress Levels Following Exposure to Formaldehyde in Lymphocytes

Authors: Malinee Pongsavee

Abstract:

Formaldehyde is the illegal chemical substance used for food preservation in fish and vegetable. It can promote carcinogenesis. Superoxide dismutases are the important antioxidative enzymes that catalyze the dismutation of superoxide anion into oxygen and hydrogen peroxide. The resultant level of oxidative stress in formaldehyde-treated lymphocytes was investigated. The formaldehyde concentrations of 0, 20, 40, 60, 80 and 120μmol/L were treated in human lymphocytes for 12 hours. After 12 treated hours, the superoxide dismutase activity change was measured in formaldehyde-treated lymphocytes. The results showed that the formaldehyde concentrations of 60, 80 and 120μmol/L significantly decreased superoxide dismutase activities in lymphocytes (P < 0.05). The change of superoxide dismutase activity in formaldehyde-treated lymphocytes may be the biomarker for detect cellular injury, such as damage to DNA, due to formaldehyde exposure.

Keywords: Formaldehyde, lymphocytes, superoxide dismutase activity.

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5202 An Alternative Proof for the Topological Entropy of the Motzkin Shift

Authors: Fahad Alsharari, Mohd Salmi Md Noorani

Abstract:

A Motzkin shift is a mathematical model for constraints on genetic sequences. In terms of the theory of symbolic dynamics, the Motzkin shift is nonsofic, and therefore, we cannot use the Perron- Frobenius theory to calculate its topological entropy. The Motzkin shift M(M,N) which comes from language theory, is defined to be the shift system over an alphabet A that consists of N negative symbols, N positive symbols and M neutral symbols. For an x in the full shift, x will be in the Motzkin subshift M(M,N) if and only if every finite block appearing in x has a non-zero reduced form. Therefore, the constraint for x cannot be bounded in length. K. Inoue has shown that the entropy of the Motzkin shift M(M,N) is log(M + N + 1). In this paper, a new direct method of calculating the topological entropy of the Motzkin shift is given without any measure theoretical discussion.

Keywords: Motzkin shift, topological entropy.

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5201 Entropy Based Data Hiding for Document Images

Authors: Swetha Kurup, Sridhar G., Sridhar V.

Abstract:

In this paper we present a novel technique for data hiding in binary document images. We use the concept of entropy in order to identify document specific least distortive areas throughout the binary document image. The document image is treated as any other image and the proposed method utilizes the standard document characteristics for the embedding process. Proposed method minimizes perceptual distortion due to embedding and allows watermark extraction without the requirement of any side information at the decoder end.

Keywords: Entropy, Steganography, Watermarking.

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5200 Effect of Gold Loading on CeO2–Fe2O3 for Oxidative Steam Reforming of Methanol

Authors: Umpawan Satitthai, Apanee Luengnaruemitchai, Erdogan Gulari

Abstract:

In this study, oxidative steam reforming of methanol (OSRM) over a Au/CeO2–Fe2O3 catalyst prepared by a depositionprecipitation (DP) method was studied to produce hydrogen in order to feed a Proton Exchange Membrane Fuel Cell (PEMFC). The support (CeO2, Fe2O3, and CeO2–Fe2O3) were prepared by precipitation and co-precipitation methods. The impact of the support composition on the catalytic performance was studied by varying the Ce/(Ce+Fe) atomic ratio, it was found that the 1%Au/CF(0.25) calcined at 300 °C exhibited the highest catalytic activity in the whole temperature studied. In addition, the effect of Au content was investigated and 3%Au/CF(0.25) exhibited the highest activity under the optimum condition in the temperature range of 200 °C to 400 °C. The catalysts were characterized by various techniques: XRD, TPR, XRF, and UV-vis.

Keywords: CeO2, Fe2O3, Gold catalyst, Hydrogen production, Methanol, Oxidative steam reforming.

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5199 Maximum Entropy Based Image Segmentation of Human Skin Lesion

Authors: Sheema Shuja Khattak, Gule Saman, Imran Khan, Abdus Salam

Abstract:

Image segmentation plays an important role in medical imaging applications. Therefore, accurate methods are needed for the successful segmentation of medical images for diagnosis and detection of various diseases. In this paper, we have used maximum entropy to achieve image segmentation. Maximum entropy has been calculated using Shannon, Renyi and Tsallis entropies. This work has novelty based on the detection of skin lesion caused by the bite of a parasite called Sand Fly causing the disease is called Cutaneous Leishmaniasis.

Keywords: Shannon, Maximum entropy, Renyi, Tsallis entropy.

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5198 Application the Statistical Conditional Entropy Function for Definition of Cause-and-Effect Relations during Primary Soil Formation

Authors: Vladimir K. Mukhomorov

Abstract:

Within the framework of a method of the information theory it is offered statistics and probabilistic model for definition of cause-and-effect relations in the coupled multicomponent subsystems. The quantitative parameter which is defined through conditional and unconditional entropy functions is introduced. The method is applied to the analysis of the experimental data on dynamics of change of the chemical elements composition of plants organs (roots, reproductive organs, leafs and stems). Experiment is directed on studying of temporal processes of primary soil formation and their connection with redistribution dynamics of chemical elements in plant organs. This statistics and probabilistic model allows also quantitatively and unambiguously to specify the directions of the information streams on plant organs.

Keywords: Chemical elements, entropy function, information, plants.

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5197 Antioxidant Activity of Germinated African Yam Bean (Sphenostylis stenocarpa) in Alloxan Diabetic Rats

Authors: Nneka N. Uchegbu

Abstract:

This study was conducted to investigate the effect of the antioxidant activity of germinated African Yam Bean (AYB) on oxidative stress markers in alloxan induced diabetic rat. Rats were randomized into three groups; control, diabetic and germinated AYB – treated diabetic rats. The Total phenol and flavonoid content and DPPH radical scavenging activity before and after germination were investigated. The glucose level, lipid peroxidation and reduced glutathione of the animals were also determined using standard technique for four weeks. Germination increased the total phenol, flavonoid and antioxidant activity of AYB extract by 19.14%, 32.28% and 57.25% respectively. The diabetic rats placed on germinated AYB diet had a significant decrease in the blood glucose and lipid peroxidation with a corresponding increase in glutathione (p<0.05). These results demonstrate that consumption of germinated AYB can be a good dietary supplement in inhibiting hyperglycemia/ hyperlipidemia and the prevention of diabetic complication associated with oxidative stress.

Keywords: African Yam Bean, Antioxidant, Diabetes, Total phenol.

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5196 Entropic Measures of a Probability Sample Space and Exponential Type (α, β) Entropy

Authors: Rajkumar Verma, Bhu Dev Sharma

Abstract:

Entropy is a key measure in studies related to information theory and its many applications. Campbell for the first time recognized that the exponential of the Shannon’s entropy is just the size of the sample space, when distribution is uniform. Here is the idea to study exponentials of Shannon’s and those other entropy generalizations that involve logarithmic function for a probability distribution in general. In this paper, we introduce a measure of sample space, called ‘entropic measure of a sample space’, with respect to the underlying distribution. It is shown in both discrete and continuous cases that this new measure depends on the parameters of the distribution on the sample space - same sample space having different ‘entropic measures’ depending on the distributions defined on it. It was noted that Campbell’s idea applied for R`enyi’s parametric entropy of a given order also. Knowing that parameters play a role in providing suitable choices and extended applications, paper studies parametric entropic measures of sample spaces also. Exponential entropies related to Shannon’s and those generalizations that have logarithmic functions, i.e. are additive have been studies for wider understanding and applications. We propose and study exponential entropies corresponding to non additive entropies of type (α, β), which include Havard and Charvˆat entropy as a special case.

Keywords: Sample space, Probability distributions, Shannon’s entropy, R`enyi’s entropy, Non-additive entropies .

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5195 Generalized Maximum Entropy Method for Cosmic Source Localization

Authors: Youssef Khmou, Said Safi, Miloud Frikel

Abstract:

The Maximum entropy principle in spectral analysis was used as an estimator of Direction of Arrival (DoA) of electromagnetic or acoustic sources impinging on an array of sensors, indeed the maximum entropy operator is very efficient when the signals of the radiating sources are ergodic and complex zero mean random processes which is the case for cosmic sources. In this paper, we present basic review of the maximum entropy method (MEM) which consists of rank one operator but not a projector, and we elaborate a new operator which is full rank and sum of all possible projectors. Two dimensional Simulation results based on Monte Carlo trials prove the resolution power of the new operator where the MEM presents some erroneous fluctuations.

Keywords: Maximum entropy, Cosmic source, Localization, operator, projector, azimuth, elevation, DoA, circular array.

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5194 Generalized Measures of Fuzzy Entropy and their Properties

Authors: K.C. Deshmukh, P.G. Khot, Nikhil

Abstract:

In the present communication, we have proposed some new generalized measure of fuzzy entropy based upon real parameters, discussed their and desirable properties, and presented these measures graphically. An important property, that is, monotonicity of the proposed measures has also been studied.

Keywords: Fuzzy numbers, Fuzzy entropy, Characteristicfunction, Crisp set, Monotonicity.

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5193 A New Approach to Image Segmentation via Fuzzification of Rènyi Entropy of Generalized Distributions

Authors: Samy Sadek, Ayoub Al-Hamadi, Axel Panning, Bernd Michaelis, Usama Sayed

Abstract:

In this paper, we propose a novel approach for image segmentation via fuzzification of Rènyi Entropy of Generalized Distributions (REGD). The fuzzy REGD is used to precisely measure the structural information of image and to locate the optimal threshold desired by segmentation. The proposed approach draws upon the postulation that the optimal threshold concurs with maximum information content of the distribution. The contributions in the paper are as follow: Initially, the fuzzy REGD as a measure of the spatial structure of image is introduced. Then, we propose an efficient entropic segmentation approach using fuzzy REGD. However the proposed approach belongs to entropic segmentation approaches (i.e. these approaches are commonly applied to grayscale images), it is adapted to be viable for segmenting color images. Lastly, diverse experiments on real images that show the superior performance of the proposed method are carried out.

Keywords: Entropy of generalized distributions, entropy fuzzification, entropic image segmentation.

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