Search results for: M.B. Dehpour

Authors: Behnoush Zare, Mojdeh Akhavan, Ahmad Reza Dehpour

Abstract:

In this study we investigate the insertion of pioglitazone, a Thiazolidinedione, into the two different sizes of Carbon nanotub. It was shown that the insertion of pioglitazone into the carbon nanotube in a water solute environment could be related to the diameter of the nanotube and in the flow of the waters via hydrophilic interactions. This encapsulated drug-carbon nanotube molecule can be further applicable in other investigations in target therapy with these agents regarding to reduce their potential toxic effects.

Keywords: Carbon Nanotube, MD Simulation, Thiazolidinedions

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Authors: I. Bagheri, M.B. Dehpour

Abstract:

The effect of moisture content and loading rate on mechanical strength of 12 brown rice grain varieties was determined. The results showed that the rupture force of brown rice grain decreased by increasing the moisture content and loading rate. The highest rupture force values was obtained at the moisture content of 8% (w.b.) and loading rate of 10 mm/min; while the lowest rupture force corresponded to the moisture content of 14% (w.b.) and loading rate of 15 mm/min. The 12 varieties were divided into three groups, namely local short grain varieties, local long grain varieties and improved long grain varieties. It was observed that the rupture strength of the three groups were statistically different from each other (P<0.01). It was revealed that the brown rice rupture at lower levels of moisture content was in the form of sudden failure with less deformation; while at higher levels of moisture content the grain rupture was in the form of gradually crushing with more deformation.

Keywords: Brown rice, loading rate, moisture content, ruptureforce

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Authors: Dehpour A. A., Eslami B., Rezaie S., Hashemian S. F., Shafie F., Kiaie M.

Abstract:

The aims of study were investigation on chemical composition essential oil and the effect of extract of Coronilla varia on antimicrobial and cytotoxicity activity. The essential oils of Coronilla varia is obtained by hydrodistillation and analyzed by (GC/MS) for determining their chemical composition and identification of their components. Antibacterial activity of plant extract was determined by disc diffusion method and anticancer activity measured by MTT assay. The major components in essential oil were Caryophyllene Oxide (60.19%), Alphacadinol (4.13%) and Homoadantaneca Robexylic Acid (3.31%). The extracts from Coronilla varia had interesting activity against Proteus mirabilis in the concentration of 700 μg/disc and did not show any activity against Staphylococus aureus, Bacillus subtillis, Klebsiella pneumonia and Entrobacter cloacae. The positive control, Ampicillin, Chloramphenicol and Cenphalothin had shown zone of inhibition resistant all bacteria. The ethanol extract of Corohilla varia inhibited on MCF7 cell lines. IC50 0.6(mg/ml) was the optimum concentration of extract from Coronilla varia inhibition of cell line growth. The MCF7 cancer cell line and Proteus mirabilis were more sensitive to Coronilla varia ethanol extract.

Keywords: Coronilla varia, Essential oil, Antibacterial, Anticancer, HeLa cell line.

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