Search results for: L. B. Gboeloh

Authors: Lebari B. Gboeloh

Abstract:

The occurrence of adult Taenia saginata in major abattoirs in Port Harcourt metropolis was investigated. Out of 514 cattle investigated, an overall prevalence of 35(6.8%) was recorded. Infected male and female cattle represented 1.2% (6/514) and 5.6% (29/514) of the overall prevalence respectively. There was a statistical significant difference (P< 0.05) in prevalence of adult Taenaia saginata between male and female cattle examined in the study area. Old cattle have a significant (P< 0.05) infestation rate than young ones. Adult Taenia saginata exists in cattle and still remains a public health concern in the study area. Deliberate effort is needed from stake-holders and the Government to design and implement programs that will lead to the prevention and possible eradication of the parasite.

Keywords: Taenia saginata, Adult, Cattle, Occurrence, Port Harcourt.

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Authors: L. B. Gboeloh, K. Elele

Abstract:

Gastrointestinal parasitic infections are common health problems in sub-Saharan Africa. A cross- sectional study was carried out to determine the prevalence of gastrointestinal parasites among workers in major abattoirs in Port Harcourt, Nigeria. These abattoirs are located in Trans-Amadi, Rumuodumaya, Mile III and Easter-by-Pass. Formol-ether concentration technique was used to isolate the ova and cysts from faecal samples. Out of 201 workers (herdsmen, butchers, and cleaners) investigated for the presence of these parasites, 89 (44.2%) were infected with one or more parasites. The prevalence of the parasites among herdsmen and cleaners was significantly (P<0.05) higher. However, there was no significant (P>0.05) difference in the prevalence of gastrointestinal parasites in relation to age. Parasites identified included Ascaris lumbricoide (33.3%), tapeworm (4.97%), Entamoeba histolytica (5.47%), hookworms (13.9%), Trichuris trichiura (9.95%), Gardia lamblia (3.48%), and Schistosoma mansoni (1.9%). The frequency of A. lumbricoide was significantly (P<0.05) higher than other parasites. Many workers (65.2%) had single infection than double (23.6%) and triple infection (11.2%). Sanitary improvements, increased level of personal hygiene, routine surveillance by public health practitioners and veterinary experts as well as hygienic operation using modern technologies to process meat at these abattoirs will go a long way to control occupational gastrointestinal parasites among workers.

Keywords: Abattoirs, Gastrointestinal parasites, Port Harcourt, Workers.

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Authors: Lebari B. Gboeloh

Abstract:

Ficus exasperata is a plant used in the traditional management of malaria in south-south Nigeria. An investigation into the effects of the ethanolic extract of the leaf of the plant on some biochemical indices in albino mice infected with Plasmodium berghei (NK 65) was conducted. 48 mice with weight range of 13-23 g were grouped into six (A, B, C, D, E, and F). Each group contained 8 mice. Groups A, B, C, D and E were infected with blood containing the parasite. Group F was not infected and served as the normal control. On the 6^th day after infection, 4 mice from each group were sacrificed and blood samples are collected for investigation. The remaining mice in each group were treated. Mice in Groups A, B and C were administered orally with 200, 300 and 500 mg/kg body weight of Ficus exasperata respectively for six days. Group D was not treated while Group F was given distilled water. Group E was treated with 5 mg/kg body weight of chloroquine. On the 6^th day post treatment, these mice were sacrificed and blood samples were collected for biochemical analysis. The results indicated that on the 6^th day post inoculation, the levels of aspartate aminotransferase (AST), alkaline phosphatase (ALP) and alanine aminotransferase (ALT) in all the mice infected with the parasite were significantly (p < 0.05) elevated. However, on the 6^th day post administration of extract, the increased levels of AST, ALP and ALT were significantly (p < 0.05) reduced in groups administered with 300 and 500 mg/kg body weight of the extract compared with groups D and F. The reduction in the levels of these enzymes is an indication that F. exasperata have no hepatotoxic effect on the mice at the dose levels administered.

Keywords: Ficus exasperata, albino mice, Plasmodium berghei, biochemical parameters.

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