Search results for: error treatment.
1725 Electron Density Discrepancy Analysis of Energy Metabolism Coenzymes
Authors: Alan Luo, Hunter N. B. Moseley
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Many macromolecular structure entries in the Protein Data Bank (PDB) have a range of regional (localized) quality issues, be it derived from X-ray crystallography, Nuclear Magnetic Resonance (NMR) spectroscopy, or other experimental approaches. However, most PDB entries are judged by global quality metrics like R-factor, R-free, and resolution for X-ray crystallography or backbone phi-psi distribution statistics and average restraint violations for NMR. Regional quality is often ignored when PDB entries are re-used for a variety of structurally based analyses. The binding of ligands, especially ligands involved in energy metabolism, is of particular interest in many structurally focused protein studies. Using a regional quality metric that provides chemically interpretable information from electron density maps, a significant number of outliers in regional structural quality was detected across X-ray crystallographic PDB entries for proteins bound to biochemically critical ligands. In this study, a series of analyses was performed to evaluate both specific and general potential factors that could promote these outliers. In particular, these potential factors were the minimum distance to a metal ion, the minimum distance to a crystal contact, and the isotropic atomic b-factor. To evaluate these potential factors, Fisher’s exact tests were performed, using regional quality criteria of outlier (top 1%, 2.5%, 5%, or 10%) versus non-outlier compared to a potential factor metric above versus below a certain outlier cutoff. The results revealed a consistent general effect from region-specific normalized b-factors but no specific effect from metal ion contact distances and only a very weak effect from crystal contact distance as compared to the b-factor results. These findings indicate that no single specific potential factor explains a majority of the outlier ligand-bound regions, implying that human error is likely as important as these other factors. Thus, all factors, including human error, should be considered when regions of low structural quality are detected. Also, the downstream re-use of protein structures for studying ligand-bound conformations should screen the regional quality of the binding sites. Doing so prevents misinterpretation due to the presence of structural uncertainty or flaws in regions of interest.
Keywords: Biomacromolecular structure, coenzyme, electron density discrepancy analysis, X-ray crystallography.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2551724 Preparation of Size Controlled Silver on Carbon from E-waste by Chemical and Electro-Kinetic Processes
Authors: Mahmoud A. Rabah
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Preparation of size controlled nano-particles of silver catalyst on carbon substrate from e-waste has been investigated. Chemical route was developed by extraction of the metals available in nitric acid followed by treatment with hydrofluoric acid. Silver metal particles deposited with an average size 4-10 nm. A stabilizer concentration of 10- 40 g/l was used. The average size of the prepared silver decreased with increase of the anode current density. Size uniformity of the silver nano-particles was improved distinctly at higher current density no more than 20mA... Grain size increased with EK time whereby aggregation of particles was observed after 6 h of reaction.. The chemical method involves adsorption of silver nitrate on the carbon substrate. Adsorbed silver ions were directly reduced to metal particles using hydrazine hydrate. Another alternative method is by treatment with ammonia followed by heating the carbon loaded-silver hydroxide at 980°C. The product was characterized with the help of XRD, XRF, ICP, SEM and TEM techniques.
Keywords: e-waste, silver catalyst, metals recovery, electrokinetic process.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25091723 Determination of Measurement Uncertainty in Extracting of Forming Limit Diagrams
Authors: M. Mahboubkhah, H. Fayazfar
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In this research, Forming Limit Diagrams for supertension sheet metals which are using in automobile industry have been obtained. The exerted strains to sheet metals have been measured with four different methods and the errors of each method have also been represented. These methods have been compared with together and the most efficient and economic way of extracting of the exerted strains to sheet metals has been introduced. In this paper total error and uncertainty of FLD extraction procedures have been derived. Determination of the measurement uncertainty in extracting of FLD has a great importance in design and analysis of the sheet metal forming process.Keywords: Forming Limit Diagram, Major and Minor Strain, Measurement Uncertainty.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20021722 Molecular Dynamics Study on Laninamivir Inhibiting Neuraminidases of H5N1 and pH1N1 Influenza a Viruses
Authors: A. Meeprasert, W. Khuntawee, S. Hannongbua, T. Rungrotmongkol
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Viral influenza A subtypes H5N1 and pandemic H1N1 (pH1N1) have worldwide emerged and transmitted. The most common anti-influenza drug for treatment of both seasonal and pandemic influenza viruses is oseltamivir that nowadays becomes resistance to influenza neuraminidase. The novel long-acting drug, laninamivir, was discovered for treatment of the patients infected with influenza B and influenza A viruses. In the present study, laninamivir complexed with wild-type strain of both H5N1 and pH1N1 viruses were comparatively determined the structures and drug-target interactions by means of molecular dynamics (MD) simulations. The results show that the hydrogen bonding interactions formed between laninamivir and its binding residues are likely similar for the two systems. Additionally, the presence of intermolecular interactions from laninamivir to the residues in the binding pocket is established through their side chains in accordance with hydrogen bond interactions.Keywords: Laninamivir, neuraminidase, H5N1, pandemic H1N1, wild-type, MD simulation
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16831721 Efficacy of Selected Mobility Exercises and Participation in Special Games on Psychomotor Abilities, Functional Abilities and Game Performance among Intellectually Disabled Children of Under 14 Age
Authors: J. Samuel Jesudoss
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The purpose of the study was to find out the efficacy of selected mobility exercises and participation in special games on psychomotor abilities, functional abilities and skill performance among intellectually disabled children of age group under 14. Thirty male students who were studying in Balar Kalvi Nilayam and YMCA College Special School, Chennai, acted as subjects for the study. They were only mild and moderate in intellectual disability. These students did not undergo any special training or coaching programme apart from their regular routine physical activity classes as a part of the curriculum in the school. They were attached at random, based on age in which 30 belonged to under 14 age group, which was divided into three equal group of ten for each experimental treatment. 10 students (Treatment group I) underwent calisthenics and special games participation, 10 students (Treatment group II) underwent aquatics and special games participation, 10 students (Treatment group III) underwent yoga and special games participation. The subjects were tested on selected criterion variables prior (pre test) and after twelve weeks of training (post test). The pre and post test data collected from three groups on functional abilities(self care, learning, capacity for independent living), psychomotor variables(static balance, eye hand coordination, simple reaction time test) and skill performance (bocce skill, badminton skill, table tennis skill) were statistically examined for significant difference, by applying the analysis ANACOVA. Whenever an 'F' ratio for adjusted test was found to be significant for adjusted post test means, Scheffe-s test was followed as a post-hoc test to determine which of the paired mean differences was significant. The result of the study showed that among under 14 age groups there was a significant improvement on selected criterion variables such as, Balance, Coordination, self-care and learning and also in Bocce, Badminton & Table Tennis skill performance, due to mobility exercises and participation in special games. However there were no significant differences among the groups.Keywords: Functional ability, intellectually disabled, Mobility exercises, Psychomotor ability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19731720 PMF, Cesium and Rubidium Nanoparticles Induce Apoptosis in A549 Cells
Authors: Faten. A. Khorshid, Gehan. A. Raouf, Salem. M. El-Hamidy, Gehan. S. Al-amri, Nourah. A. Alotaibi, Taha A. Kumosani
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Cancer becomes one of the leading cause of death in many countries over the world. Fourier-transform infrared (FTIR) spectra of human lung cancer cells (A549) treated with PMF (natural product extracted from PM 701) for different time intervals were examined. Second derivative and difference method were taken in comparison studies. Cesium (Cs) and Rubidium (Rb) nanoparticles in PMF were detected by Energy Dispersive X-ray attached to Scanning Electron Microscope SEM-EDX. Characteristic changes in protein secondary structure, lipid profile and changes in the intensities of DNA bands were identified in treated A549 cells spectra. A characteristic internucleosomal ladder of DNA fragmentation was also observed after 30 min of treatment. Moreover, the pH values were significantly increases upon treatment due to the presence of Cs and Rb nanoparticles in the PMF fraction. These results support the previous findings that PMF is selective anticancer agent and can produce apoptosis to A549 cells.Keywords: Apoptosis, FTIR spectroscopy, pH therapy, Scanning Electron Microscope- Energy Dispersive X-ray (SEMEDX).
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 43321719 Approximating Fixed Points by a Two-Step Iterative Algorithm
Authors: Safeer Hussain Khan
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In this paper, we introduce a two-step iterative algorithm to prove a strong convergence result for approximating common fixed points of three contractive-like operators. Our algorithm basically generalizes an existing algorithm..Our iterative algorithm also contains two famous iterative algorithms: Mann iterative algorithm and Ishikawa iterative algorithm. Thus our result generalizes the corresponding results proved for the above three iterative algorithms to a class of more general operators. At the end, we remark that nothing prevents us to extend our result to the case of the iterative algorithm with error terms.
Keywords: Contractive-like operator, iterative algorithm, fixed point, strong convergence.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20221718 Antenna Array Beamforming Using Neural Network
Authors: Maja Sarevska, Abdel-Badeeh M. Salem
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This paper considers the problem of Null-Steering beamforming using Neural Network (NN) approach for antenna array system. Two cases are presented. First, unlike the other authors, the estimated Direction Of Arrivals (DOAs) are used for antenna array weights NN-based determination and the imprecise DOAs estimations are taken into account. Second, the blind null-steering beamforming is presented. In this case the antenna array outputs are presented at the input of the NN without DOAs estimation. The results of computer simulations will show much better relative mean error performances of the first NN approach compared to the NNbased blind beamforming.
Keywords: Beamforming, DOAs, neural network.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24161717 Low Energy Technology for Leachate Valorisation
Authors: Jesús M. Martín, Francisco Corona, Dolores Hidalgo
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Landfills present long-term threats to soil, air, groundwater and surface water due to the formation of greenhouse gases (methane gas and carbon dioxide) and leachate from decomposing garbage. The composition of leachate differs from site to site and also within the landfill. The leachates alter with time (from weeks to years) since the landfilled waste is biologically highly active and their composition varies. Mainly, the composition of the leachate depends on factors such as characteristics of the waste, the moisture content, climatic conditions, degree of compaction and the age of the landfill. Therefore, the leachate composition cannot be generalized and the traditional treatment models should be adapted in each case. Although leachate composition is highly variable, what different leachates have in common is hazardous constituents and their potential eco-toxicological effects on human health and on terrestrial ecosystems. Since leachate has distinct compositions, each landfill or dumping site would represent a different type of risk on its environment. Nevertheless, leachates consist always of high organic concentration, conductivity, heavy metals and ammonia nitrogen. Leachate could affect the current and future quality of water bodies due to uncontrolled infiltrations. Therefore, control and treatment of leachate is one of the biggest issues in urban solid waste treatment plants and landfills design and management. This work presents a treatment model that will be carried out "in-situ" using a cost-effective novel technology that combines solar evaporation/condensation plus forward osmosis. The plant is powered by renewable energies (solar energy, biomass and residual heat), which will minimize the carbon footprint of the process. The final effluent quality is very high, allowing reuse (preferred) or discharge into watercourses. In the particular case of this work, the final effluents will be reused for cleaning and gardening purposes. A minority semi-solid residual stream is also generated in the process. Due to its special composition (rich in metals and inorganic elements), this stream will be valorized in ceramic industries to improve the final products characteristics.
Keywords: Forward osmosis, landfills, leachate valorization, solar evaporation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 9551716 Dead-Reckoning Error Calibration using Celling Looking Vision Camera
Authors: Jae-Young Choi, Sung-Gaun Kim
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This paper suggests a calibration method to reduce errors occurring due to mobile robot sliding during location estimation using the Dead-reckoning. Due to sliding of the mobile robot caused between its wheels and the road surface while on free run, location estimation can be erroneous. Sliding especially occurs during cornering of mobile robot. Therefore, in order to reduce these frequent sliding errors in cornering, we calibrated the mobile robot-s heading values using a vision camera and templates of the ceiling.Keywords: Dead-reckoning, Localization, Odomerty, Vision Camera
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17831715 The Behavior of Dam Foundation Reinforced by Stone Columns: Case Study of Kissir Dam-Jijel
Authors: Toufik Karech, Abderahmen Benseghir, Tayeb Bouzid
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This work presents a 2D numerical simulation of an earth dam to assess the behavior of its foundation after a treatment by stone columns. This treatment aims to improve the bearing capacity, to increase the mechanical properties of the soil, to accelerate the consolidation, to reduce the settlements and to eliminate the liquefaction phenomenon in case of seismic excitation. For the evaluation of the pore pressures, the position of the phreatic line and the flow network was defined, and a seepage analysis was performed with the software MIDAS Soil Works. The consolidation calculation is performed through a simulation of the actual construction stages of the dam. These analyzes were performed using the Mohr-Coulomb soil model and the results are compared with the actual measurements of settlement gauges implanted in the dam. An analysis of the bearing capacity was conducted to show the role of stone columns in improving the bearing capacity of the foundation.
Keywords: Earth dam, dam foundation, numerical simulation, stone columns, seepage analysis, consolidation, bearing capacity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 11261714 Response of King Abdulla Canal Water to the Upgrade of As Samra WWTP
Authors: Abbas S. Al-Omari, Zain M. Al-Houri
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The response of King Abdulla Canal (KAC) water to the upgrade of As Samra Wastewater Treatment Plant which discharges its effluent to the Zarqa River is investigated. Time series quality data that extends between October 2005 and December 2009 obtained by a state of the art telemetric monitoring system were analyzed for COD, EC, TP and TN at two monitoring stations located upstream and downstream of the confluence of the Zarqa River with KAC. The samples- means and the t-test showed that there has been significant improvement in the quality of the KAC water for COD, and TP. However, the improvement in the TN was found statistically insignificant, whereas the EC of the KAC was unaffected by the upgrade. Comparing the selected parameters with the standards and guidelines for using treated wastewater in irrigation showed that the KAC water has improved towards meeting the required standards and guidelines for treated wastewater reuse in irrigation.
Keywords: As Samra wastewater treatment plant, Telemetric monitoring system, Treated wastewater, Water quality monitoring, Zarqa River watershed.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16771713 A New Rigid Fistulectomy Set for Minimally Invasive “Core-Out“ Excision of High Anal Fistulas
Authors: Siamak Najarian, Meysam Esmaeili, Mohsen Towliat Kashani
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In this article, we propose a new surgical device for circumferentially excision of high anal fistulas in a minimally invasive manner. The new apparatus works on the basis of axially rotating and moving a tubular blade along a fistulous tract straightened using a rigid straight guidewire. As the blade moves along the tract, its sharp circular cutting edge circumferentially separates approximately 2.25 mm thickness of tract encircling the rigid guidewire. We used the new set to excise two anal fistulas in a 62-year-old male patient, an extrasphincteric type and a long tract with no internal opening. With regard to the results of this test, the new device can be considered as a sphincter preserving mechanism for treatment of high anal fistulas. Consequently, a major reduction in the risk of fecal incontinence, recurrence rate, convalescence period and patient morbidity may be achieved using the new device for treatment of fistula-in-ano.Keywords: Fecal Incontinence, Fistulectomy, High Anal Fistula, Minimally Invasive.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17311712 Comparison of Multi-User Detectors of DS-CDMA System
Authors: Kavita Khairnar, Shikha Nema
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DS-CDMA system is well known wireless technology. This system suffers from MAI (Multiple Access Interference) caused by Direct Sequence users. Multi-User Detection schemes were introduced to detect the users- data in presence of MAI. This paper focuses on linear multi-user detection schemes used for data demodulation. Simulation results depict the performance of three detectors viz-conventional detector, Decorrelating detector and Subspace MMSE (Minimum Mean Square Error) detector. It is seen that the performance of these detectors depends on the number of paths and the length of Gold code used.Keywords: Cross Correlation Matrix, MAI, Multi-UserDetection, Multipath Effect.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21131711 Exponential State Estimation for Neural Networks with Leakage, Discrete and Distributed Delays
Authors: Liyuan Wang, Shouming Zhong
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In this paper, the design problem of state estimator for neural networks with the mixed time-varying delays are investigated by constructing appropriate Lyapunov-Krasovskii functionals and using some effective mathematical techniques. In order to derive several conditions to guarantee the estimation error systems to be globally exponential stable, we transform the considered systems into the neural-type time-delay systems. Then with a set of linear inequalities(LMIs), we can obtain the stable criteria. Finally, three numerical examples are given to show the effectiveness and less conservatism of the proposed criterion.
Keywords: State estimator, Neural networks, Globally exponential stability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16641710 Artificial Neural Networks for Identification and Control of a Lab-Scale Distillation Column Using LABVIEW
Authors: J. Fernandez de Canete, S. Gonzalez-Perez, P. del Saz-Orozco
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LABVIEW is a graphical programming language that has its roots in automation control and data acquisition. In this paper we have utilized this platform to provide a powerful toolset for process identification and control of nonlinear systems based on artificial neural networks (ANN). This tool has been applied to the monitoring and control of a lab-scale distillation column DELTALAB DC-SP. The proposed control scheme offers high speed of response for changes in set points and null stationary error for dual composition control and shows robustness in presence of externally imposed disturbance.
Keywords: Distillation, neural networks, LABVIEW, monitoring, identification, control.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 29191709 An Accurate Method for Phylogeny Tree Reconstruction Based on a Modified Wild Dog Algorithm
Authors: Essam Al Daoud
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This study solves a phylogeny problem by using modified wild dog pack optimization. The least squares error is considered as a cost function that needs to be minimized. Therefore, in each iteration, new distance matrices based on the constructed trees are calculated and used to select the alpha dog. To test the suggested algorithm, ten homologous genes are selected and collected from National Center for Biotechnology Information (NCBI) databanks (i.e., 16S, 18S, 28S, Cox 1, ITS1, ITS2, ETS, ATPB, Hsp90, and STN). The data are divided into three categories: 50 taxa, 100 taxa and 500 taxa. The empirical results show that the proposed algorithm is more reliable and accurate than other implemented methods.Keywords: Least squares, neighbor joining, phylogenetic tree, wild dogpack.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13921708 Comparison of the Existing Methods in Determination of the Characteristic Polynomial
Authors: Mohammad Saleh Tavazoei, Mohammad Haeri
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This paper presents comparison among methods of determination of the characteristic polynomial coefficients. First, the resultant systems from the methods are compared based on frequency criteria such as the closed loop bandwidth, gain and phase margins. Then the step responses of the resultant systems are compared on the basis of the transient behavior criteria including overshoot, rise time, settling time and error (via IAE, ITAE, ISE and ITSE integral indices). Also relative stability of the systems is compared together. Finally the best choices in regards to the above diverse criteria are presented.Keywords: Characteristic Polynomial, Transient Response, Filters, Stability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20141707 Effect of Partial Rootzone Drying on Growth, Yield and Biomass Partitioning of a Soilless Tomato Crop
Authors: N. Affi, A. El Fadl, M. El Otmani, M.C. Benismail, L.M. Idrissi
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The object of the present research was to assess the effects of partial rootzone drying (PRD) on tomato growth, productivity, biomass allocation and water use efficiency (WUE). Plants were grown under greenhouse, on a sand substrate. Three treatments were applied: a control that was fully and conventionally irrigated, PRD-70 and PRD-50 in which, respectively, 70% and 50% of water requirements were supplied using PRD. Alternation of irrigation between the two root halves took place each three days. The Control produces the highest total yield (252tons/ha). In terms of fruit number, PRD-50 showed 23% and 16% less fruits than PRD-70 and control, respectively. Fruit size was affected by treatment with PRD-50 treatment producing 66% and 53% more class 3 fruits than, control and PRD-70, respectively. For plant growth, the difference was not significant when comparing control to PRD-70 but was significant when comparing PRD-70 and control to PRD-50. No effect was on total biomass but root biomass was higher for stressed plants compared to control. WUE was 66% and 27% higher for PRD-50 and PRD-70 respectively compared to control.
Keywords: Biomass, growth, partial rootzone drying, water use efficiency yield.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20701706 Applications of High Intensity Ultrasound to Modify Millet Protein Concentrate Functionality
Authors: B. Nazari, M. A. Mohammadifar, S. Shojaee-Aliabadi, L. Mirmoghtadaie
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Millets as a new source of plant protein were not used in food applications due to its poor functional properties. In this study, the effect of high intensity ultrasound (frequency: 20 kHz, with contentious flow) (US) in 100% amplitude for varying times (5, 12.5, and 20 min) on solubility, emulsifying activity index (EAI), emulsion stability (ES), foaming capacity (FC), and foaming stability (FS) of millet protein concentrate (MPC) were evaluated. In addition, the structural properties of best treatments such as molecular weight and surface charge were compared with the control sample to prove the US effect. The US treatments significantly (P<0.05) increased the solubility of the native MPC (65.8±0.6%) at all sonicated times with the maximum solubility that is recorded at 12.5 min treatment (96.9±0.82 %). The FC of MPC was also significantly affected by the US treatment. Increase in sonicated time up to 12.5 min significantly increased the FC of native MPC (271.03±4.51 ml), but higher increase reduced it significantly. Minimal improvements were observed in the FS of all sonicated MPC compared to the native MPC. Sonicated time for 12.5 min affected the EAI and ES of the native MPC more markedly than 5 and 20 min that may be attributed to higher increase in proteins tendency to adsorption at the oil and water interfaces after the US treatment at this time. SDS-PAGE analysis showed changes in the molecular weight of MPC that attributed to shearing forces created by cavitation phenomenon. Also, this phenomenon caused an increase in the exposure of more amino acids with negative charge in the surface of US treated MPC, that was demonstrated by Zetasizer data. High intensity ultrasound, as a green technology, can significantly increase the functional properties of MPC and can make this usable for food applications.Keywords: Millet protein concentrate, Functional properties, Structural properties, High intensity ultrasound.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17341705 Application of Artificial Neural Networks for Temperature Forecasting
Authors: Mohsen Hayati, Zahra Mohebi
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In this paper, the application of neural networks to study the design of short-term temperature forecasting (STTF) Systems for Kermanshah city, west of Iran was explored. One important architecture of neural networks named Multi-Layer Perceptron (MLP) to model STTF systems is used. Our study based on MLP was trained and tested using ten years (1996-2006) meteorological data. The results show that MLP network has the minimum forecasting error and can be considered as a good method to model the STTF systems.Keywords: Artificial neural networks, Forecasting, Weather, Multi-layer perceptron.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 43571704 A Retrospective Cross-Sectional Study on the Prevalence and Factors Associated with Virological Non-Suppression among HIV-Positive Adult Patients on Antiretroviral Therapy in Woliso Town, Oromia, Ethiopia
Authors: Teka Haile, Behailu Hawulte, Solomon Alemayehu
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Background: HIV virological failure still remains a problem in HV/AIDS treatment and care. This study aimed to describe the prevalence and identify the factors associated with viral non-suppression among HIV-positive adult patients on antiretroviral therapy in Woliso Town, Oromia, Ethiopia. Methods: A retrospective cross-sectional study was conducted among 424 HIV-positive patient’s attending antiretroviral therapy (ART) in Woliso Town during the period from August 25, 2020 to August 30, 2020. Data collected from patient medical records were entered into Epi Info version 2.3.2.1 and exported to SPSS version 21.0 for analysis. Logistic regression analysis was done to identify factors associated with viral load non-suppression, and statistical significance of odds ratios were declared using 95% confidence interval and p-value < 0.05. Results: A total of 424 patients were included in this study. The mean age (± SD) of the study participants was 39.88 (± 9.995) years. The prevalence of HIV viral load non-suppression was 55 (13.0%) with 95% CI (9.9-16.5). Second-line ART treatment regimen (Adjusted Odds Ratio (AOR) = 8.98, 95% Confidence Interval (CI): 2.64, 30.58) and routine viral load testing (AOR = 0.01, 95% CI: 0.001, 0.02) were significantly associated with virological non-suppression. Conclusion: Virological non-suppression was high, which hinders the achievement of the third global 95 target. The second-line regimen and routine viral load testing were significantly associated with virological non-suppression. It suggests the need to assess the effectiveness of antiretroviral drugs for epidemic control. It also clearly shows the need to decentralize third-line ART treatment for those patients in need.Keywords: Virological non-suppression, HIV-positive, ART, Woliso Town, Ethiopia.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5871703 Tensile Behavior of Spheroidizing Heat Treated High Carbon Steel
Authors: Seok Hong Min, Tae Kwon Ha
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Spheroidization heat treatment was conducted on the SK85 high carbon steel sheets with various initial microstructures obtained after cold rolling by various reduction ratios at a couple of annealing temperatures. On the high carbon steel sheet with fine pearlite microstructure, obtained by soaking at 800oC for 2hr in a box furnace and then annealing at 570oC for 5min in a salt bath furnace followed by water quenching, cold rolling was conducted by reduction ratios of 20, 30, and 40%. Heat treatment for spheroidization was carried out at 600 and 720oC for the various time intervals from 0.1 to 32 hrs. Area fraction of spheroidized cementite was measured with an image analyzer as a function of cold reduction ratios and duration times. Tensile tests were carried out at room temperature on the spheoidized high carbon steel.
Keywords: High carbon steel, SK85, pearlite, cementite, shperoidization, tensile behavior.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 41321702 Aerobic Treatment of Oily Wastewater: Effect of Aeration and Sludge Concentration to Pollutant Reduction and PHB Accumulation
Authors: Budhi Primasari, Shaliza Ibrahim, M Suffian M Annuar, Lim Xung Ian Remmie
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This study is aimed to investigate feasibility of the aerobic biological process to treat oily wastewater from palm oil food industry. Effect of aeration and sludge concentrations are studied. Raw sludge and raw wastewater was mixed and acclimatized for five days in a stirred tank reactor. The aeration rate (no aeration, low; 1.5L/min and high rate; 2L/min) and sludge concentration (3675, 7350, and 11025mg/L of VSS) were varied. Responses of process were pH, COD, oil and grease, VSS, and PHB content. It was found that the treatment can remove 85.1 to 97.1 % of COD and remove 12.9 to 54.8% of oil & grease. The PHB yield was found to be within 0.15% to 2.4% as PHB/VSS ratio and 0.01% to 0.12% as PHB/COD removed. The higher aeration results a high COD removal and oil & grease removal, while experiment without aeration gives better PHB yield. Higher sludge concentrations (11025mg/L VSS) give higher removal of oil & grease while moderate sludge concentration (7350mg/L VSS) give better result in COD removal. Higher PHB yield is obtained in low sludge concentration (3675mg/L).Keywords: oily wastewater, COD, PHB, oil and grease
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 42501701 Agent-based Simulation for Blood Glucose Control in Diabetic Patients
Authors: Sh. Yasini, M. B. Naghibi-Sistani, A. Karimpour
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This paper employs a new approach to regulate the blood glucose level of type I diabetic patient under an intensive insulin treatment. The closed-loop control scheme incorporates expert knowledge about treatment by using reinforcement learning theory to maintain the normoglycemic average of 80 mg/dl and the normal condition for free plasma insulin concentration in severe initial state. The insulin delivery rate is obtained off-line by using Qlearning algorithm, without requiring an explicit model of the environment dynamics. The implementation of the insulin delivery rate, therefore, requires simple function evaluation and minimal online computations. Controller performance is assessed in terms of its ability to reject the effect of meal disturbance and to overcome the variability in the glucose-insulin dynamics from patient to patient. Computer simulations are used to evaluate the effectiveness of the proposed technique and to show its superiority in controlling hyperglycemia over other existing algorithmsKeywords: Insulin Delivery rate, Q-learning algorithm, Reinforcement learning, Type I diabetes.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21981700 Application of a Dual Satellite Geolocation System on Locating Sweeping Interference
Authors: M. H. Chan
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This paper describes an application of a dual satellite geolocation (DSG) system on identifying and locating the unknown source of uplink sweeping interference. The geolocation system integrates the method of joint time difference of arrival (TDOA) and frequency difference of arrival (FDOA) with ephemeris correction technique which successfully demonstrated high accuracy in interference source location. The factors affecting the location error were also discussed.Keywords: Dual satellite geolocation system, DGS, geolocation, TDOA/FDOA, and sweeping interference
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 40391699 Turing Pattern in the Oregonator Revisited
Authors: Elragig Aiman, Dreiwi Hanan, Townley Stuart, Elmabrook Idriss
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In this paper, we reconsider the analysis of the Oregonator model. We highlight an error in this analysis which leads to an incorrect depiction of the parameter region in which diffusion driven instability is possible. We believe that the cause of the oversight is the complexity of stability analyses based on eigenvalues and the dependence on parameters of matrix minors appearing in stability calculations. We regenerate the parameter space where Turing patterns can be seen, and we use the common Lyapunov function (CLF) approach, which is numerically reliable, to further confirm the dependence of the results on diffusion coefficients intensities.Keywords: Diffusion driven instability, common Lyapunov function (CLF), turing pattern, positive-definite matrix.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10481698 Comparison of Classical and Ultrasound-Assisted Extractions of Hyphaene thebaica Fruit and Evaluation of Its Extract as Antibacterial Activity in Reducing Severity of Erwinia carotovora
Authors: Hanan Moawad, Naglaa M. Abd EL-Rahman
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Erwinia carotovora var. carotovora is the main cause of soft rot in potatoes. Hyphaene thebaica was studied for biocontrol of E. carotovora which inhibited growth of E. carotovora on solid medium, a comparative study of classical and ultrasound-assisted extractions of Hyphaene thebaica fruit. The use of ultrasound decreased significant the total time of treatment and increase the total amount of crude extract. The crude extract was subjected to determine the in vitro, by a bioassay technique revealed that the treatment of paper disks with ultrasound extraction of Hyphaene thebaica reduced the growth of pathogen and produced inhibition zones up to 38mm in diameter. The antioxidant activity of ultrasound-ethanolic extract of Doum fruits (Hyphaene thebaica) was determined. Data obtained showed that the extract contains the secondary metabolites such as Tannins, Saponin, Flavonoids, Phenols, Steroids, Terpenoids, Glycosides and Alkaloids.
Keywords: Ultrasound, classical extract, Biological control, Erwinia carotovora, Hyphaene thebaica.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 28101697 Auto Regressive Tree Modeling for Parametric Optimization in Fuzzy Logic Control System
Authors: Arshia Azam, J. Amarnath, Ch. D. V. Paradesi Rao
Abstract:
The advantage of solving the complex nonlinear problems by utilizing fuzzy logic methodologies is that the experience or expert-s knowledge described as a fuzzy rule base can be directly embedded into the systems for dealing with the problems. The current limitation of appropriate and automated designing of fuzzy controllers are focused in this paper. The structure discovery and parameter adjustment of the Branched T-S fuzzy model is addressed by a hybrid technique of type constrained sparse tree algorithms. The simulation result for different system model is evaluated and the identification error is observed to be minimum.Keywords: Fuzzy logic, branch T-S fuzzy model, tree modeling, complex nonlinear system.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13891696 A Low-Voltage Current-Mode Wheatstone Bridge using CMOS Transistors
Authors: Ebrahim Farshidi
Abstract:
This paper presents a new circuit arrangement for a current-mode Wheatstone bridge that is suitable for low-voltage integrated circuits implementation. Compared to the other proposed circuits, this circuit features severe reduction of the elements number, low supply voltage (1V) and low power consumption (<350uW). In addition, the circuit has favorable nonlinearity error (<0.35%), operate with multiple sensors and works by single supply voltage. The circuit employs MOSFET transistors, so it can be used for standard CMOS fabrication. Simulation results by HSPICE show high performance of the circuit and confirm the validity of the proposed design technique.Keywords: Wheatstone bridge, current-mode, low-voltage, MOS.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3022