Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 3

Search results for: M. Khalifeh Gholi

3 Evaluation of Negative Air Ions in Bioaerosol Removal: Indoor Concentration of Airborne Bacterial and Fungal in Residential Building in Qom City, Iran

Authors: Z. Asadgol, A. Nadali, H. Arfaeinia, M. Khalifeh Gholi, R. Fateh, M. Fahiminia


The present investigation was conducted to detect the type and concentrations of bacterial and fungal bioaerosols in one room (bedroom) of each selected residential building located in different regions of Qom during February 2015 (n=9) to July 2016 (n=11). Moreover, we evaluated the efficiency of negative air ions (NAIs) in bioaerosol reduction in indoor air in residential buildings. In the first step, the mean concentrations of bacterial and fungal in nine sampling sites evaluated in winter were 744 and 579 colony forming units (CFU)/m3, while these values were 1628.6 and 231 CFU/m3 in the 11 sampling sites evaluated in summer, respectively. The most predominant genera between bacterial and fungal in all sampling sites were detected as Micrococcus spp. and Staphylococcus spp. and also, Aspergillus spp. and Penicillium spp., respectively. The 95% and 45% of sampling sites have bacterial and fungal concentrations over the recommended levels, respectively. In the removal step, we achieved a reduction with a range of 38% to 93% for bacterial genera and 25% to 100% for fungal genera by using NAIs. The results suggested that NAI is a highly effective, simple and efficient technique in reducing the bacterial and fungal concentration in the indoor air of residential buildings.

Keywords: bacterial, fungal, negative air ions (NAIs), indoor air, Iran

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2 Investigation of Anatomical Components of Mosques with the Approach of Attention to Islamic Wisdom

Authors: Farshad Negintaji, Hamid Reza Zeraat Pisheh, Mahshid Ghanea, Zahra Khalifeh, Mohammad Bagher Rahami


This study has been examined the anatomical components of mosques with the approach of attending to Islamic wisdom and investigated the distinction between the anatomical design of mosques (traditional and modern) by considering the category of perception in Islamic architecture. To this end, this article by reviewing the theoretical and empirical literature of mosques' anatomy and the role of anatomy on the architectural design of Iranian mosques by examining the quantitative and qualitative indicators and in order to understand and identify the anatomy of mosques, indicators such as: entrance, portico, minarets, domes, bedchamber and pool have been used. The aim of this study has been to investigate materials, the functional properties, technology, sizes and fitness of (traditional and modern) mosques. For this purpose, a questionnaire was prepared in which the anatomical and spiritual elements of the mosque shape have been questioned. Research is related to field and is of descriptive, analytical and inferential type and quantitative and qualitative indicators have been examined.

Keywords: Islamic wisdom, Islamic architecture, mosque anatomy, the minaret, dome, bedchamber, entrance, pool, perception

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1 Investigation Of The Possible Beneficial And Protective Effects Of An Ethanolic Extract From Sarcopoterium spinosum Fruits

Authors: Hawraa Zbeeb, Hala Khalifeh, Mohamad Khalil, Francesca Storace, Francesca Baldini, Giulio Lupidi, Laura Vergani


Sarcopoterium spinosum, a widely distributed spiny shrubbelonging to the Rosaceae family, isrich in essential and beneficial constituents. In fact, S. spinosum fruits and roots are traditionally used as herbal medicinein the eastern Mediterranean landscape, and this shrub is mentioned as a medicinal plant in a large number of ethnobotanical surveys. Aqueous root extracts from S. spinosum are used by traditional medicinal practitioners for weight loss, treatment of diabetes, and pain. Moreover, the anti-diabetic activity of S. spinosum root extract is reported in different studies, but the beneficial effects of aerial parts, especially fruits, has not been elucidated yet. The aim of the present study was to investigate the in vitro antioxidant and lipid-lowering properties of an ethanolic extract from S. spinosum fruits using both hepatic (FaO) and endothelial (HECV) cells in the attempt to evaluate its possible employment as a nutraceutical supplement. First of all, in vitro spectrophotometric assays were employed to characterize the extract. The total phenol content (TPC) was evaluated by Folin–Ciocalteuspectrophotometric method, the radical scavenging activity was tested by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assays. After that, the beneficial effects of the extract were tested on cells. FaO cells treated for 3 hours with 0.75 mM oleate/palmitate mix (1:2 molar ratio) mimic in vitroa moderate hepato-steatosis. HECV cells exposed for 1 hour to 100 µM H2O2mimic, an oxidative insult leading to oxidative stress condition. After the metabolic and oxidative insult, both cell lines were treated with increasing concentrations of theS. spinosum extract (1, 10, 25 µg/mL) for 24 hours. The results showed the S. spinosumethanolic extract is rather rich in phenols (TPC of 18.6 mgGAE/g dry extract). Moreover, the extract showed a good scavenging abilityin vitro(IC50 15.9 µg/mland 10.9 µg/mlmeasured by DPPH and ABTS assays, respectively). When the extract was tested on cells, we observed that it could ameliorate some markers of cell dysfunction. The three concentrations of the extractled to a significant decrease in the intracellular triglyceride (TG) contentin steatoticFaO cells measured by spectrophotometric assay. On the other hand, HECV cells treated with increasing concentrations of the extract did not result in a significant decrease in both lipid peroxidation measured by the Thiobarbituric Acid Reactive Substances (TBARS) assay and in reactive oxygen species (ROS) production measured by fluorometric analysis after DCF staining. Interestingly, the ethanolic extract was able to accelerate the wound repair of confluentHECV cells respect to H2O2-insulted cells as measured by T-scratch assay. Taken together, these results seem to indicate that the ethanol extract from S. spinosum fruits is rich in phenol compounds and plays considerable lipid lowering activity in vitroon steatotichepatocytes, and accelerates wound healing repair on endothelial cells. In light of that, the ethanolic extract from S. spinosumfruits could be a potential candidate for nutraceutical applications.

Keywords: sarcopoterium spinosum fruits, ethanolic extract, phenolic compounds, lipid-lowering activity, antioxidant activity

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