Search results for: discrete manufacturing
1078 Assessing Efficiency Trends in the Indian Sugar Industry
Authors: S. P. Singh
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This paper measures technical and scale efficiencies of 40 Indian sugar companies for the period from 2004-05 to 2013-14. The efficiencies are estimated through input-oriented DEA models using one output variable—value of output (VOP) and five input variables—capital cost (CA), employee cost (EMP), raw material (RW), energy & fuel (E&F) and other manufacturing expenses (OME). The sugar companies are classified into integrated and non-integrated categories to know which one achieves higher level of efficiency. Sources of inefficiency in the industry are identified through decomposing the overall technical efficiency (TE) into pure technical efficiency (PTE) and scale efficiency (SE). The paper also estimates input-reduction targets for relatively inefficient companies and suggests measures to improve their efficiency level. The findings reveal that the TE does not evince any trend rather it shows fluctuations across years, largely due to erratic and cyclical pattern of sugar production. Further, technical inefficiency in the industry seems to be driven more by the managerial inefficiency than the scale inefficiency, which implies that TE can be improved through better conversion of inputs into output.Keywords: DEA, slacks, sugar industry, technical efficiency
Procedia PDF Downloads 3181077 Scientific and Regulatory Challenges of Advanced Therapy Medicinal Products
Authors: Alaa Abdellatif, Gabrièle Breda
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Background. Advanced therapy medicinal products (ATMPs) are innovative therapies that mainly target orphan diseases and high unmet medical needs. ATMP includes gene therapy medicinal products (GTMP), somatic cell therapy medicinal products (CTMP), and tissue-engineered therapies (TEP). Since legislation opened the way in 2007, 25 ATMPs have been approved in the EU, which is about the same amount as the U.S. Food and Drug Administration. However, not all of the ATMPs that have been approved have successfully reached the market and retained their approval. Objectives. We aim to understand all the factors limiting the market access to very promising therapies in a systemic approach, to be able to overcome these problems, in the future, with scientific, regulatory and commercial innovations. Further to recent reviews that focus either on specific countries, products, or dimensions, we will address all the challenges faced by ATMP development today. Methodology. We used mixed methods and a multi-level approach for data collection. First, we performed an updated academic literature review on ATMP development and their scientific and market access challenges (papers published between 2018 and April 2023). Second, we analyzed industry feedback from cell and gene therapy webinars and white papers published by providers and pharmaceutical industries. Finally, we established a comparative analysis of the regulatory guidelines published by EMA and the FDA for ATMP approval. Results: The main challenges in bringing these therapies to market are the high development costs. Developing ATMPs is expensive due to the need for specialized manufacturing processes. Furthermore, the regulatory pathways for ATMPs are often complex and can vary between countries, making it challenging to obtain approval and ensure compliance with different regulations. As a result of the high costs associated with ATMPs, challenges in obtaining reimbursement from healthcare payers lead to limited patient access to these treatments. ATMPs are often developed for orphan diseases, which means that the patient population is limited for clinical trials which can make it challenging to demonstrate their safety and efficacy. In addition, the complex manufacturing processes required for ATMPs can make it challenging to scale up production to meet demand, which can limit their availability and increase costs. Finally, ATMPs face safety and efficacy challenges: dangerous adverse events of these therapies like toxicity related to the use of viral vectors or cell therapy, starting material and donor-related aspects. Conclusion. As a result of our mixed method analysis, we found that ATMPs face a number of challenges in their development, regulatory approval, and commercialization and that addressing these challenges requires collaboration between industry, regulators, healthcare providers, and patient groups. This first analysis will help us to address, for each challenge, proper and innovative solution(s) in order to increase the number of ATMPs approved and reach the patientsKeywords: advanced therapy medicinal products (ATMPs), product development, market access, innovation
Procedia PDF Downloads 761076 Proposal for Knowledge-Based Virtual Community System (KBVCS) for Enhancing Knowledge Sharing in Mechatronics System Diagnostic and Repair
Authors: Adetoba B. Tiwalola, Adedeji W. Oyediran, Yekini N. Asafe, Akinwole A. Kikelomo
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Mechatronics is synergistic integration of mechanical engineering, with electronics and intelligent computer control in the design and manufacturing of industrial products and processes. Automobile (auto car, motor car or car is a wheeled motor vehicle used for transporting passengers, which also carries its own engine or motor) is a mechatronic system which served as major means of transportation around the world. Virtually all community has a need for automobile. This makes automobile issues as related to diagnostic and repair interesting to all communities. Consequent to the diversification of skill in diagnosing automobile faults and approaches in solving some problems and innovation in automobile industry. It is appropriate to say that repair and diagnostic of automobile will be better enhanced if community has opportunity of sharing knowledge and idea globally. This paper discussed the desirable elements in automobile as mechatronics system and present conceptual framework of virtual community model for knowledge sharing among automobile users.Keywords: automobile, automobile users, knowledge sharing, mechatronics system, virtual community
Procedia PDF Downloads 4401075 Bayesian Parameter Inference for Continuous Time Markov Chains with Intractable Likelihood
Authors: Randa Alharbi, Vladislav Vyshemirsky
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Systems biology is an important field in science which focuses on studying behaviour of biological systems. Modelling is required to produce detailed description of the elements of a biological system, their function, and their interactions. A well-designed model requires selecting a suitable mechanism which can capture the main features of the system, define the essential components of the system and represent an appropriate law that can define the interactions between its components. Complex biological systems exhibit stochastic behaviour. Thus, using probabilistic models are suitable to describe and analyse biological systems. Continuous-Time Markov Chain (CTMC) is one of the probabilistic models that describe the system as a set of discrete states with continuous time transitions between them. The system is then characterised by a set of probability distributions that describe the transition from one state to another at a given time. The evolution of these probabilities through time can be obtained by chemical master equation which is analytically intractable but it can be simulated. Uncertain parameters of such a model can be inferred using methods of Bayesian inference. Yet, inference in such a complex system is challenging as it requires the evaluation of the likelihood which is intractable in most cases. There are different statistical methods that allow simulating from the model despite intractability of the likelihood. Approximate Bayesian computation is a common approach for tackling inference which relies on simulation of the model to approximate the intractable likelihood. Particle Markov chain Monte Carlo (PMCMC) is another approach which is based on using sequential Monte Carlo to estimate intractable likelihood. However, both methods are computationally expensive. In this paper we discuss the efficiency and possible practical issues for each method, taking into account the computational time for these methods. We demonstrate likelihood-free inference by performing analysing a model of the Repressilator using both methods. Detailed investigation is performed to quantify the difference between these methods in terms of efficiency and computational cost.Keywords: Approximate Bayesian computation(ABC), Continuous-Time Markov Chains, Sequential Monte Carlo, Particle Markov chain Monte Carlo (PMCMC)
Procedia PDF Downloads 2021074 Model-Based Process Development for the Comparison of a Radial Riveting and Roller Burnishing Process in Mechanical Joining Technology
Authors: Tobias Beyer, Christoph Friedrich
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Modern simulation methodology using finite element models is nowadays a recognized tool for product design/optimization. Likewise, manufacturing process design is increasingly becoming the focus of simulation methodology in order to enable sustainable results based on reduced real-life tests here as well. In this article, two process simulations -radial riveting and roller burnishing- used for mechanical joining of components are explained. In the first step, the required boundary conditions are developed and implemented in the respective simulation models. This is followed by process space validation. With the help of the validated models, the interdependencies of the input parameters are investigated and evaluated by means of sensitivity analyses. Limit case investigations are carried out and evaluated with the aid of the process simulations. Likewise, a comparison of the two joining methods to each other becomes possible.Keywords: FEM, model-based process development, process simulation, radial riveting, roller burnishing, sensitivity analysis
Procedia PDF Downloads 1081073 Manufacturing of Nano Zeolite by Planetary Ball Mill and Investigation of the Effects on Concrete
Authors: Kourosh Kosari
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This study is engineering the properties of concrete containing natural nano zeolite as supplementary cementitious material in the blended Portland-cement based binder in amounts of 5,7 and 10% by mass. Crashing of clinoptilolite zeolite is performed by means of planetary ball mill. Two types of concrete along with water to cementitious material ratio (W/(C + P)) in 0.45 and 0.4 at the ages of 7, 28 and 90 days and were compared with each other. The effect of these additives on mechanical properties (compressive and tensile strength) and durability has been investigated by Electrical Resistivity (ER) and Rapid Chloride Penetration Test (RCPT) at the ages 28 and 90 days. Scanning Electron Microscopy (SEM) and X-Ray Diffraction (XRD) revealed that nanoparticles of natural clinoptilolite could improve quality of concrete. As a result of the tests, decrease in penetration of chloride ion and increase electrical resistivity significantly that are appropriate option for controlling of corrosion in reinforced concrete structures but increase of mechanical characteristics is not considerable.Keywords: ball mill, durability, mechanical properties, nano zeolite
Procedia PDF Downloads 3201072 Smart Production Planning: The Case of Aluminium Foundry
Authors: Samira Alvandi
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In the context of the circular economy, production planning aims to eliminate waste and emissions and maximize resource efficiency. Historically production planning is challenged through arrays of uncertainty and complexity arising from the interdependence and variability of products, processes, and systems. Manufacturers worldwide are facing new challenges in tackling various environmental issues such as climate change, resource depletion, and land degradation. In managing the inherited complexity and uncertainty and yet maintaining profitability, the manufacturing sector is in need of a holistic framework that supports energy efficiency and carbon emission reduction schemes. The proposed framework addresses the current challenges and integrates simulation modeling with optimization for finding optimal machine-job allocation to maximize throughput and total energy consumption while minimizing lead time. The aluminium refinery facility in western Sydney, Australia, is used as an exemplar to validate the proposed framework.Keywords: smart production planning, simulation-optimisation, energy aware capacity planning, energy intensive industries
Procedia PDF Downloads 761071 Immobilization of Superoxide Dismutase Enzyme on Layered Double Hydroxide Nanoparticles
Authors: Istvan Szilagyi, Marko Pavlovic, Paul Rouster
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Antioxidant enzymes are the most efficient defense systems against reactive oxygen species, which cause severe damage in living organisms and industrial products. However, their supplementation is problematic due to their high sensitivity to the environmental conditions. Immobilization on carrier nanoparticles is a promising research direction towards the improvement of their functional and colloidal stability. In that way, their applications in biomedical treatments and manufacturing processes in the food, textile and cosmetic industry can be extended. The main goal of the present research was to prepare and formulate antioxidant bionanocomposites composed of superoxide dismutase (SOD) enzyme, anionic clay (layered double hydroxide, LDH) nanoparticle and heparin (HEP) polyelectrolyte. To characterize the structure and the colloidal stability of the obtained compounds in suspension and solid state, electrophoresis, dynamic light scattering, transmission electron microscopy, spectrophotometry, thermogravimetry, X-ray diffraction, infrared and fluorescence spectroscopy were used as experimental techniques. LDH-SOD composite was synthesized by enzyme immobilization on the clay particles via electrostatic and hydrophobic interactions, which resulted in a strong adsorption of the SOD on the LDH surface, i.e., no enzyme leakage was observed once the material was suspended in aqueous solutions. However, the LDH-SOD showed only limited resistance against salt-induced aggregation and large irregularly shaped clusters formed during short term interval even at lower ionic strengths. Since sufficiently high colloidal stability is a key requirement in most of the applications mentioned above, the nanocomposite was coated with HEP polyelectrolyte to develop highly stable suspensions of primary LDH-SOD-HEP particles. HEP is a natural anticoagulant with one of the highest negative line charge density among the known macromolecules. The experimental results indicated that it strongly adsorbed on the oppositely charged LDH-SOD surface leading to charge inversion and to the formation of negatively charged LDH-SOD-HEP. The obtained hybrid materials formed stable suspension even under extreme conditions, where classical colloid chemistry theories predict rapid aggregation of the particles and unstable suspensions. Such a stabilization effect originated from electrostatic repulsion between the particles of the same sign of charge as well as from steric repulsion due to the osmotic pressure raised during the overlap of the polyelectrolyte chains adsorbed on the surface. In addition, the SOD enzyme kept its structural and functional integrity during the immobilization and coating processes and hence, the LDH-SOD-HEP bionanocomposite possessed excellent activity in decomposition of superoxide radical anions, as revealed in biochemical test reactions. In conclusion, due to the improved colloidal stability and the good efficiency in scavenging superoxide radical ions, the developed enzymatic system is a promising antioxidant candidate for biomedical or other manufacturing processes, wherever the aim is to decompose reactive oxygen species in suspensions.Keywords: clay, enzyme, polyelectrolyte, formulation
Procedia PDF Downloads 2681070 Determining the Mode II Intra Ply Energy Release Rate of Composites Made of Prepreg
Authors: Philip Rose, Markus Linke, David Busquets
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The distinction between interlaminar and intralaminar fracture toughness has already been investigated by several authors. For loading mode I, the double cantilever beam specimens were often used for the interlaminar fracture toughness and the compact tension specimen for the intralaminar fracture toughness. In order to minimize the influence of the different specimen geometries, a method was developed which allows the determination of both the interlaminar and the intralaminar fracture toughness on an almost identical specimen geometry. However, as this method is not applicable to prepreg semi-finished products, a further modification was developed, which is also suitable for prepreg laminates. After the successful application for the investigation of mode I with this method, the application of the method for loading mode II is presented in this paper. In addition to manufacturing differences, due to an additional fiber ply in which the controlled crack growth takes place, the adapted test procedure is also explained. By comparing the test results of standardized end-notched flexure (ENF) specimens with those of the modified ENF specimen, the difference between the interlaminar and intralaminar fracture toughness of the material Hexply 8552/IM7 is shown.Keywords: ENF, fracture toughness, interlaminar, mode II
Procedia PDF Downloads 1371069 Standard and Processing of Photodegradable Polyethylene
Authors: Nurul-Akidah M. Yusak, Rahmah Mohamed, Noor Zuhaira Abd Aziz
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The introduction of degradable plastic materials into agricultural sectors has represented a promising alternative to promote green agriculture and environmental friendly of modern farming practices. Major challenges of developing degradable agricultural films are to identify the most feasible types of degradation mechanisms, composition of degradable polymers and related processing techniques. The incorrect choice of degradable mechanisms to be applied during the degradation process will cause premature losses of mechanical performance and strength. In order to achieve controlled process of agricultural film degradation, the compositions of degradable agricultural film also important in order to stimulate degradation reaction at required interval of time and to achieve sustainability of the modern agricultural practices. A set of photodegradable polyethylene based agricultural film was developed and produced, following the selective optimization of processing parameters of the agricultural film manufacturing system. Example of agricultural films application for oil palm seedlings cultivation is presented.Keywords: photodegradable polyethylene, plasticulture, processing schemes
Procedia PDF Downloads 5181068 Developed CNN Model with Various Input Scale Data Evaluation for Bearing Faults Prognostics
Authors: Anas H. Aljemely, Jianping Xuan
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Rolling bearing fault diagnosis plays a pivotal issue in the rotating machinery of modern manufacturing. In this research, a raw vibration signal and improved deep learning method for bearing fault diagnosis are proposed. The multi-dimensional scales of raw vibration signals are selected for evaluation condition monitoring system, and the deep learning process has shown its effectiveness in fault diagnosis. In the proposed method, employing an Exponential linear unit (ELU) layer in a convolutional neural network (CNN) that conducts the identical function on positive data, an exponential nonlinearity on negative inputs, and a particular convolutional operation to extract valuable features. The identification results show the improved method has achieved the highest accuracy with a 100-dimensional scale and increase the training and testing speed.Keywords: bearing fault prognostics, developed CNN model, multiple-scale evaluation, deep learning features
Procedia PDF Downloads 2101067 Development of Ceramic Spheres Buoyancy Modules for Deep-Sea Oil Exploration
Authors: G. Blugan, B. Jiang, J. Thornberry, P. Sturzenegger, U. Gonzenbach, M. Misson, D. Cartlidge, R. Stenerud, J. Kuebler
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Low-cost ceramic spheres were developed and manufactured from the engineering ceramic aluminium oxide. Hollow spheres of 50 mm diameter with a wall thickness of 0.5-1.0 mm were produced via an adapted slip casting technique. It was possible to produce the spheres with good repeatability and with no defects or failures in the spheres due to the manufacturing process. The spheres were developed specifically for use in buoyancy devices for deep-sea exploration conditions at depths of 3000 m below sea level. The spheres with a 1.0 mm wall thickness exhibit a buoyancy of over 54% while the spheres with a 0.5 mm wall thickness exhibit a buoyancy of over 73%. The mechanical performance of the spheres was confirmed by performing a hydraulic burst pressure test on individual spheres. With a safety factor of 3, all spheres with 1.0 mm wall thickness survived a hydraulic pressure of greater than 150 MPa which is equivalent to a depth of more than 5000 m below sea level. The spheres were then incorporated into a buoyancy module. These hollow aluminium oxide ceramic spheres offer an excellent possibility of deep-sea exploration to depths greater than the currently used technology.Keywords: buoyancy, ceramic spheres, deep-sea, oil exploration
Procedia PDF Downloads 4151066 Optimization of High Flux Density Design for Permanent Magnet Motor
Authors: Dong-Woo Kang
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This paper presents an optimal magnet shape of a spoke-shaped interior permanent magnet synchronous motor by using ferrite magnets. Generally, the permanent magnet motor used the ferrite magnets has lower output power and efficiency than a rare-earth magnet motor, because the ferrite magnet has lower magnetic energy than the rare-earth magnet. Nevertheless, the ferrite magnet motor is used to many industrial products owing to cost effectiveness. In this paper, the authors propose a high power density design of the ferrite permanent magnet synchronous motor. Furthermore, because the motor design has to be taken a manufacturing process into account, the design is simulated by using the finite element method for analyzing the demagnetization, the magnetizing, and the structure stiffness. Especially, the magnet shape and dimensions are decided for satisfying these properties. Finally, the authors design an optimal motor for applying our system. That final design is manufactured and evaluated from experimentations.Keywords: demagnetization, design optimization, magnetic analysis, permanent magnet motors
Procedia PDF Downloads 3771065 In Situ Laser-Induced Synthesis of Copper Microstructures with High Catalytic Properties and Sensory Characteristics
Authors: Maxim Panov, Evgenia Khairullina, Sergey Ermakov, Oleg Gundobin, Vladimir Kochemirovsky
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The continuous in situ laser-induced catalysis proceeding via generation and growth of nano-sized copper particles was discussed. Also, the simple and lost-cost method for manufacturing of microstructural copper electrodes was proposed. The electrochemical properties of these electrodes were studied by cyclic voltammetry and impedance spectroscopy. The surface of the deposited copper structures (electrodes) was investigated by X-ray photoelectron spectroscopy and atomic force microscopy. These microstructures are highly conductive and porous with a dispersion of pore size ranging from 50 nm to 50 μm. An analytical response of the fabricated copper electrode is 30 times higher than those observed for a pure bulk copper with similar geometric parameters. A study of sensory characteristics for hydrogen peroxide determination showed that the value of Faraday current at the fabricated copper electrode is 2-2.5 orders of magnitude higher than for etalon one.Keywords: laser-induced deposition, electrochemical electrodes, non-enzymatic sensors, copper
Procedia PDF Downloads 2461064 Association of Phosphorus and Magnesium with Fat Indices in Children with Metabolic Syndrome
Authors: Mustafa M. Donma, Orkide Donma
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Metabolic syndrome (MetS) is a disease associated with obesity. It is a complicated clinical problem possibly affecting body composition as well as macrominerals. These parameters gain further attention, particularly in the pediatric population. The aim of this study is to investigate the amount of discrete body composition fractions in groups that differ in the severity of obesity. Also, the possible associations with calcium (Ca), phosphorus (P), magnesium (Mg) will be examined. The study population was divided into four groups. Twenty-eight, 29, 34, and 34 children were involved in Group 1 (healthy), 2 (obese), 3 (morbid obese), and 4 (MetS), respectively. Institutional Ethical Committee approved the study protocol. Informed consent forms were obtained from the participants. The classification of obese groups was performed based upon the recommendations of the World Health Organization. Metabolic syndrome components were defined. Serum Ca, P, Mg concentrations were measured. Within the scope of body composition, fat mass, fat-free mass, protein mass, mineral mass were determined by a body composition monitor using bioelectrical impedance analysis technology. Weight, height, waist circumference, hip circumference, head circumference, and neck circumference values were recorded. Body mass index, diagnostic obesity notation model assessment index, fat mass index, and fat-free mass index values were calculated. Data were statistically evaluated and interpreted. There was no statistically significant difference among the groups in terms of Ca and P concentrations. Magnesium concentrations differed between Group 1 and Group 4. Strong negative correlations were detected between P as well as Mg and fat mass index as well as diagnostic obesity notation model assessment index in Group 4, the group, which comprised morbid obese children with MetS. This study emphasized unique associations of P and Mg minerals with diagnostic obesity notation model assessment index and fat mass index during the evaluation of morbid obese children with MetS. It was also concluded that diagnostic obesity notation model assessment index and fat mass index were more proper indices in comparison with body mass index and fat-free mass index for the purpose of defining body composition in children.Keywords: children, fat mass, fat-free mass, macrominerals, obesity
Procedia PDF Downloads 1531063 Revolution Biopolibag System Based on Water Hyacinth's Fiber as a Solution for Environmental Friendly Seeding and Seedling
Authors: Supriady R. P. Siregar, Rizki Barkah Aulia, Dhiya Fadilla Dewi
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Polybag is a plastic that is used to seed plants. The common type that used for polybag is a synthetic that made from petroleum such as polyethylene. Beside the character of the raw material that are non-renewable and limited, synthetic polybag ability to disintegrate in the environment is very low. According to that situation, we need a solution to overcome these problems by creating an environmentally friendly polybag. In this research, using the water hyacinth plant fibers (Eichornia crassipes) as a major component in manufacturing the environmentally friendly polybag, the water hyacinth (Eichornia crassipes) contains approximately 60% cellulose. The research method used is an experiment by testing the mechanical characters and biodegradability bio-polybag water hyacinth fibers (Eichornia crassipes) on three medium that is dissolved in water, river water and buried in soil. The research shows bio-polybag of hyacinth fibers can rapidly degraded. This study is expected to be the beginning of the creation bio-polybag of water hyacinth fiber (Eichornia crassipes) and can be applied in agriculture.Keywords: revolution, biopolybag, renewable, environment
Procedia PDF Downloads 2401062 Manufacturing of Twist-Free Surfaces by Magnetism Aided Machining Technologies
Authors: Zs. Kovács, Zs. J. Viharos, J. Kodácsy
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As a well-known conventional finishing process, the grinding is commonly used to manufacture seal mating surfaces and bearing surfaces, but is also creates twisted surfaces. The machined surfaces by turning or grinding usually have twist structure on the surfaces, which can convey lubricants such as conveyor screw. To avoid this phenomenon, have to use special techniques or machines, for example start-stop turning, tangential turning, ultrasonic protection or special toll geometries. All of these solutions have high cost and difficult usability. In this paper, we describe a system and summarize the results of the experimental research carried out mainly in the field of Magnetic Abrasive Polishing (MAP) and Magnetic Roller Burnishing (MRB). These technologies are simple and also green while able to produce twist-free surfaces. During the tests, C45 normalized steel was used as workpiece material which was machined by simple and Wiper geometrical turning inserts in a CNC turning lathe. After the turning, the MAP and MRB technologies can be used directly to reduce the twist of surfaces. The evaluation was completed by advanced measuring and IT equipment.Keywords: magnetism, finishing, polishing, roller burnishing, twist-free
Procedia PDF Downloads 5761061 Detection of Extrusion Blow Molding Defects by Airflow Analysis
Authors: Eva Savy, Anthony Ruiz
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In extrusion blow molding, there is great variability in product quality due to the sensitivity of the machine settings. These variations lead to unnecessary rejects and loss of time. Yet production control is a major challenge for companies in this sector to remain competitive within their market. Current quality control methods only apply to finished products (vision control, leak test...). It has been shown that material melt temperature, blowing pressure, and ambient temperature have a significant impact on the variability of product quality. Since blowing is a key step in the process, we have studied this parameter in this paper. The objective is to determine if airflow analysis allows the identification of quality problems before the full completion of the manufacturing process. We conducted tests to determine if it was possible to identify a leakage defect and an obstructed defect, two common defects on products. The results showed that it was possible to identify a leakage defect by airflow analysis.Keywords: extrusion blow molding, signal, sensor, defects, detection
Procedia PDF Downloads 1511060 Recovery of Waste: Feasibility and Sustainable Application of Residues from Drinking Water Treatment in Building Materials
Authors: Flavio Araujo, Julio Lima, Paulo Scalize, Antonio Albuquerque, Isabela Santos
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The aim of this study was to perform the physicochemical characterizations of the residue generated in the Meia-Ponte Water Treatment Plant, seeking to obtain normative parameters and consider sustainable alternatives for reincorporation of the residues in the productive chain for manufacturing various materials construction. In order to reduce the environmental liabilities generated by sanitation companies and discontinue unsustainable forms of disposal as the launching of the residue in the rivers, disposal in landfills or burning it, because such ways pollute watercourses, ground and air. The analyzes performed: Granulometry, identification of clay minerals, Scanning Electron Microscopy, and X-Ray Diffraction demonstrated the potential application of residues to replace the soil and sand, because it has characteristics compatible with small aggregate and can be used as feedstock for the manufacture of materials as ceramic and soil-cement bricks, mortars, interlocking floors and concrete artifacts.Keywords: recovery of waste, residue, sustainable, water treatment plant, WTR
Procedia PDF Downloads 5441059 The Management of Behcet's Disease Patient's Mandibular Total Edentulism with Custom Made Implant Supported Bar Retainer: A Case Report
Authors: Faruk Emir, Simel Ayyıldız, Cem Şahin
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Behçet’s disease or Behçet’s syndrome is a chronic and multi-systemic inflammatory disease of unknown cause. This syndrome often presents with mucous membrane ulceration and ocular problems. As a systemic disease Behcet includes triple-symptom complex of recurrent oral aphthous ulcers, genital ulcers, and uveitis. Nearly all patients present with some form of painful oral mucocutaneous ulcerations in the form of aphthous ulcers. The aim of the treatment plan for Behçet’s Disease patients is to eliminate oral problems and increase the patient comfort.This clinical report represents the prosthodontic rehabilitation of Behcet’s disease patients mandibular total edentulism with the use of implant supported prosthesis that planned on custom abutments and bar retainers via CAD/CAM technology and patient satisfaction has been achieved in function and aesthetics.Keywords: Behçet’s disease, CAD/CAM, custom-made manufacturing, titanium milled bar retainer
Procedia PDF Downloads 3341058 Create a Brand Value Assessment Model to Choosing a Cosmetic Brand in Tehran Combining DEMATEL Techniques and Multi-Stage ANFIS
Authors: Hamed Saremi, Suzan Taghavy, Seyed Mohammad Hanif Sanjari, Mostafa Kahali
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One of the challenges in manufacturing and service companies to provide a product or service is recognized Brand to consumers in target markets. They provide most of their processes under the same capacity. But the constant threat of devastating internal and external resources to prevent a rise Brands and more companies are recognizing the stages are bankrupt. This paper has tried to identify and analyze effective indicators of brand equity and focuses on indicators and presents a model of intelligent create a model to prevent possible damage. In this study, the identified indicators of brand equity are based on literature study and according to expert opinions, set of indicators By techniques DEMATEL Then to used Multi-Step Adaptive Neural-Fuzzy Inference system (ANFIS) to design a multi-stage intelligent system for assessment of brand equity.Keywords: brand, cosmetic product, ANFIS, DEMATEL
Procedia PDF Downloads 4171057 Multi-Band Frequency Conversion Scheme with Multi-Phase Shift Based on Optical Frequency Comb
Authors: Tao Lin, Shanghong Zhao, Yufu Yin, Zihang Zhu, Wei Jiang, Xuan Li, Qiurong Zheng
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A simple operated, stable and compact multi-band frequency conversion and multi-phase shift is proposed to satisfy the demands of multi-band communication and radar phase array system. The dual polarization quadrature phase shift keying (DP-QPSK) modulator is employed to support the LO sideband and the optical frequency comb simultaneously. Meanwhile, the fiber is also used to introduce different phase shifts to different sidebands. The simulation result shows that by controlling the DC bias voltages and a C band microwave signal with frequency of 4.5 GHz can be simultaneously converted into other signals that cover from C band to K band with multiple phases. It also verifies that the multi-band and multi-phase frequency conversion system can be stably performed based on current manufacturing art and can well cope with the DC drifting. It should be noted that the phase shift of the converted signal also partly depends of the length of the optical fiber.Keywords: microwave photonics, multi-band frequency conversion, multi-phase shift, conversion efficiency
Procedia PDF Downloads 2541056 Analysis of Different Resins in Web-to-Flange Joints
Authors: W. F. Ribeiro, J. L. N. Góes
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The industrial process adds to engineering wood products features absent in solid wood, with homogeneous structure and reduced defects, improved physical and mechanical properties, bio-deterioration, resistance and better dimensional stability, improving quality and increasing the reliability of structures wood. These features combined with using fast-growing trees, make them environmentally ecological products, ensuring a strong consumer market. The wood I-joists are manufactured by the industrial profiles bonding flange and web, an important aspect of the production of wooden I-beams is the adhesive joint that bonds the web to the flange. Adhesives can effectively transfer and distribute stresses, thereby increasing the strength and stiffness of the composite. The objective of this study is to evaluate different resins in a shear strain specimens with the aim of analyzing the most efficient resin and possibility of using national products, reducing the manufacturing cost. First was conducted a literature review, where established the geometry and materials generally used, then established and analyzed 8 national resins and produced six specimens for each.Keywords: engineered wood products, structural resin, wood i-joist, Pinus taeda
Procedia PDF Downloads 2781055 Reshoring Strategies for Enhanced Supply Chain Resilience: A Comprehensive Analysis of Procurement Challenges and Solutions in the United States
Authors: Emilia Segun-Ajao
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The strategy of relocation aimed at strengthening supply chain resilience in the United States is examined, taking into account recent global disturbances and vulnerabilities in offshore manufacturing. It explains the procurement challenges faced by enterprises and offers solutions to mitigate risks and improve resilience. Through the analysis of innovative approaches, including technological advances, policy considerations, and strategic frameworks, this study provides insights to decision-makers about the complexity of supply chain management. Reshoring has gained attention as a strategy to improve supply chain resilience in the face of global disruptions. This analysis focuses on the importance of relocating as a multifaceted approach to strengthening supply chains, advocating economic benefits, technological advances, and policy frameworks to create a more robust supply landscape in the United States.Keywords: collaborative partnerships, supply chain resilience, procurement challenges, technology adoption
Procedia PDF Downloads 631054 Estimating the Properties of Polymer Concrete Using the Response Surface Method
Authors: Oguz Ugurkan Akkaya, Alpaslan Sipahi, Ozgur Firat Pamukcu, Murat Yasar, Tolga Guler, Arif Ulu, Ferit Cakir
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With the increase in human population, expansion, and renovation of cities, infrastructure systems today need to be manufactured to be more durable and long-lasting. The most cost-effective and durable manufacturing of components is a general problem of all engineering disciplines. Therefore, it is important to determine the most optimal components. This study mainly focuses on the most optimal component design of the polymer concrete. For this purpose, the lower and upper limits of the three main components of the polymer concrete are determined. The effects of these three principal components on the compressive strength, tensile strength, and unit price of polymer concrete are estimated using the response surface method. Box-Behnken Design is used in designing the experiments. Compressive strength, tensile strength, and unit prices are successfully estimated with variance ratios (R²) of 0.82, 0.92, and 0.90, respectively, and the optimum mixture quantity is determined.Keywords: Box-Behnken Design, compressive strength, mechanical tests, polymer concrete, tensile strength
Procedia PDF Downloads 1721053 Mapping of Textile Waste Generation across the Value Chains Operating in the Textile Industry
Authors: Veena Nair, Srikanth Prakash, Mayuri Wijayasundara
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Globally, the textile industry is a key contributor to the generation of solid waste which gets landfilled. Textile waste generation generally occurs in three stages, namely: producer waste, pre-consumer waste, and post-consumer waste. However, the different processes adopted in textile material extraction, manufacturing, and use have their respective impact in terms of the quantity of waste being diverted to landfills. The study is focused on assessing the value chains of the two most common textile fibres: cotton and polyester, catering to a broad categories of apparel products. This study attempts to identify and evaluate the key processes adopted by the textile industry at each of the stages in their value chain in terms of waste generation. The different processes identified in each of the stages in the textile value chains are mapped to their respective contribution in generating fibre waste which eventually gets diverted to landfill. The results of the study are beneficial for the overall industry in terms of improving the traceability of waste in the value chains and the selection of processes and behaviours facilitating the reduction of environmental impacts associated with landfills.Keywords: textile waste, textile value chains, landfill waste, waste mapping
Procedia PDF Downloads 2061052 Quality Management and Service Organization
Authors: Fatemeh Khalili Varnamkhasti
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In recent times, there has been a notable shift in the application of Total Quality Management (TQM) from manufacturing to service organizations, prompting numerous studies on the subject. TQM has firmly established itself across various sectors, emerging as an approach to process improvement, waste reduction, business optimization, and quality performance. Many researchers and academics have recognized the relevance of TQM for sustainable competitive advantage, particularly in service organizations. In light of this, the purpose of this research study is to explore the applicability of TQM within the service framework. The study delves into existing literature on TQM in service organizations and examines the reasons for its occasional shortcomings. Ultimately, the paper provides systematic guidelines for the effective implementation of TQM in service organizations. The findings of this study offer a much-improved understanding of TQM and its practices, shedding light on the evolution of service organizations. Additionally, the study highlights key insights from recent research on TQM in service organizations and proposes a ten-step approach for the successful implementation of TQM in the service sector. This framework aims to provide service managers and professionals with a comprehensive understanding of TQM fundamentals and encourages a deeper exploration of TQM theory.Keywords: quality, control, service, management, teamwork
Procedia PDF Downloads 541051 Application of Nanofibers in Heavy Metal (HM) Filtration
Authors: Abhijeet Kumar, Palaniswamy N. K.
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Heavy metal contamination in water sources endangers both the environment and human health. Various water filtration techniques have been employed till now for purification and removal of hazardous metals from water. Among all the existing methods, nanofibres have emerged as a viable alternative for effective heavy metal removal in recent years because of their unique qualities, such as large surface area, interconnected porous structure, and customizable surface chemistry. Among the numerous manufacturing techniques, solution blow spinning has gained popularity as a versatile process for producing nanofibers with customized properties. This paper seeks to offer a complete overview of the use of nanofibers for heavy metal filtration, particularly those produced using solution blow spinning. The review discusses current advances in nanofiber materials, production processes, and heavy metal removal performance. Furthermore, the field's difficulties and future opportunities are examined in order to direct future research and development activities.Keywords: heavy metals, nanofiber composite, filter membranes, adsorption, impaction
Procedia PDF Downloads 681050 Computational Approaches for Ballistic Impact Response of Stainless Steel 304
Authors: A. Mostafa
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This paper presents a numerical study on determination of ballistic limit velocity (V50) of stainless steel 304 (SS 304) used in manufacturing security screens. The simulated ballistic impact tests were conducted on clamped sheets with different thicknesses using ABAQUS/Explicit nonlinear finite element (FE) package. The ballistic limit velocity was determined using three approaches, namely: numerical tests based on material properties, FE calculated residual velocities and FE calculated residual energies. Johnson-Cook plasticity and failure criterion were utilized to simulate the dynamic behaviour of the SS 304 under various strain rates, while the well-known Lambert-Jonas equation was used for the data regression for the residual velocity and energy model. Good agreement between the investigated numerical methods was achieved. Additionally, the dependence of the ballistic limit velocity on the sheet thickness was observed. The proposed approaches present viable and cost-effective assessment methods of the ballistic performance of SS 304, which will support the development of robust security screen systems.Keywords: ballistic velocity, stainless steel, numerical approaches, security screen
Procedia PDF Downloads 1641049 Bread Quality Improvement with Special Novel Additives
Authors: Mónika Bartalné-Berceli, Eszter Izsó, Szilveszter Gergely, András Salgó
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Nowadays a significant portion of the Earth's population does not have access to healthy food. Either because they can not afford them or because they do not know which they are. The aim of the VIIth Framework CHANCE project (Nr. 266331) supported by the European Union has been to develop relatively cheap food favorable from nutritional point of view and has acceptable quality for consumers. Within the project we dealt with manufacturing of bread belonging to basic foods. We had examined the enrichment of bread products with four kinds of bran, with a special milling product of grain industry (aleurone flour) and with a soy-based sprouted additive. The applied concentration of the six mentioned additives has been optimized and the physical and sensory properties of the bread products were monitored. The weight of the enriched breads increased slightly, however the volume and height decreased slightly compared to the corresponding data of the control bread. The composition of the final product is favorable affected by these additives having highly preferred composition from nutritional point of view.Keywords: bread products, brans, YASO, aleurone flour
Procedia PDF Downloads 387