Search results for: Gaussian-Wishart emission model
16868 Toehold Mediated Shape Transition of Nucleic Acid Nanoparticles
Authors: Emil F. Khisamutdinov
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Development of functional materials undergoing structural transformations in response to an external stimulus such as environmental changes (pH, temperature, etc.), the presence of particular proteins, or short oligonucleotides are of great interest for a variety of applications ranging from medicine to electronics. The dynamic operations of most nucleic acid (NA) devices, including circuits, nano-machines, and biosensors, rely on networks of NA strand displacement processes in which an external or stimulus strand displaces a target strand from a DNA or RNA duplex. The rate of strand displacement can be greatly increased by the use of “toeholds,” single-stranded regions of the target complex to which the invading strand can bind to initiate the reaction, forming additional base pairs that provide a thermodynamic driving force for transformation. Herein, we developed a highly robust nanoparticle shape transition, sequentially transforming DNA polygons from one shape to another using the toehold-mediated DNA strand displacement technique. The shape transformation was confirmed by agarose gel electrophoresis and atomic force microscopy. Furthermore, we demonstrate that our approach is applicable for RNA shape transformation from triangle to square, which can be detected by fluorescence emission from malachite green binding RNA aptamer. Using gel-shift and fluorescence assays, we demonstrated efficient transformation occurs at isothermal conditions (37°C) that can be implemented within living cells as reporter molecules. This work is intended to provide a simple, cost-effective, and straightforward model for the development of biosensors and regulatory devices in nucleic acid nanotechnology.Keywords: RNA nanotechnology, bionanotechnology, toehold mediated DNA switch, RNA split fluorogenic aptamers
Procedia PDF Downloads 7916867 Seat Assignment Model for Student Admissions Process at Saudi Higher Education Institutions
Authors: Mohammed Salem Alzahrani
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In this paper, student admission process is studied to optimize the assignment of vacant seats with three main objectives. Utilizing all vacant seats, satisfying all program of study admission requirements and maintaining fairness among all candidates are the three main objectives of the optimization model. Seat Assignment Method (SAM) is used to build the model and solve the optimization problem with help of Northwest Coroner Method and Least Cost Method. A closed formula is derived for applying the priority of assigning seat to candidate based on SAM.Keywords: admission process model, assignment problem, Hungarian Method, Least Cost Method, Northwest Corner Method, SAM
Procedia PDF Downloads 49816866 On the Mathematical Modelling of Aggregative Stability of Disperse Systems
Authors: Arnold M. Brener, Lesbek Tashimov, Ablakim S. Muratov
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The paper deals with the special model for coagulation kernels which represents new control parameters in the Smoluchowski equation for binary aggregation. On the base of the model the new approach to evaluating aggregative stability of disperse systems has been submitted. With the help of this approach the simple estimates for aggregative stability of various types of hydrophilic nano-suspensions have been obtained.Keywords: aggregative stability, coagulation kernels, disperse systems, mathematical model
Procedia PDF Downloads 30916865 Analyzing Business Model Choices and Sustainable Value Capturing: A Multiple Case Study of Sharing Economy Business Models
Authors: Minttu Laukkanen, Janne Huiskonen
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This study investigates the sharing economy business models as examples of the sustainable business models. The aim is to contribute to the limited literature on sharing economy in connection with sustainable business models by explaining sharing economy business models value capturing. Specifically, this research answers the following question: How business model choices affect captured sustainable value? A multiple case study approach is applied in this study. Twenty different successful sharing economy business models focusing on consumer business and covering four main areas, accommodation, mobility, food, and consumer goods, are selected for analysis. The secondary data available on companies’ websites, previous research, reports, and other public documents are used. All twenty cases are analyzed through the sharing economy business model framework and sustainable value analysis framework using qualitative data analysis. This study represents general sharing economy business model value attributes and their specifications, i.e. sustainable value propositions for different stakeholders, and further explains the sustainability impacts of different sharing economy business models through captured and uncaptured value. In conclusion, this study represents how business model choices affect sustainable value capturing through eight business model attributes identified in this study. This paper contributes to the research on sustainable business models and sharing economy by examining how business model choices affect captured sustainable value. This study highlights the importance of careful business model and sustainability impacts analyses including the triple bottom line, multiple stakeholders and value captured and uncaptured perspectives as well as sustainability trade-offs. It is not self-evident that sharing economy business models advance sustainability, and business model choices does matter.Keywords: sharing economy, sustainable business model innovation, sustainable value, value capturing
Procedia PDF Downloads 17216864 Experimental Study on Floating Breakwater Anchored by Piles
Authors: Yessi Nirwana Kurniadi, Nira Yunita Permata
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Coastline is vulnerable to coastal erosion which damage infrastructure and buildings. Floating breakwaters are applied in order to minimize material cost but still can reduce wave height. In this paper, we investigated floating breakwater anchored by piles based on experimental study in the laboratory with model scale 1:8. Two type of floating model were tested with several combination wave height, wave period and surface water elevation to determined transmission coefficient. This experimental study proved that floating breakwater with piles can prevent wave height up to 27 cm. The physical model shows that ratio of depth to wave length is less than 0.6 and ratio of model width to wave length is less than 0.3. It is confirmed that if those ratio are less than those value, the transmission coefficient is 0.5. The result also showed that the first type model of floating breakwater can reduce wave height by 60.4 % while the second one can reduce up to 55.56 %.Keywords: floating breakwater, experimental study, pile, transimission coefficient
Procedia PDF Downloads 53016863 Structural, Optical and Electrical Properties of MnxZnO1-X Nanocrystals Synthesized by Sol-Gel Method
Authors: K. C. Gayithri, S. K. Naveen Kumar
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ZnO is one of the most important semiconductor materials, non toxic, biocompatible, antibacterial properties for research and it is used in many biomedical applications. MnxZn1-xO nano thin films were prepared by a spin coating sol-gel method on silicon substrate. The structural, optical, electrical properties of Mn Doped ZnO are studied by using X-rd, FESEM, UV-Visible spectrophotometer. The X-rd reveals that the sample shows hexagonal wurtzits structure. Surface morphology and thickness of the sample are characterized by field emission scanning electron microscopy. Absorption and transmission spectra are studied by UV-Visible spectrophotometer. The electrical properties are measured by TCR meter.Keywords: transition metals, Mn doped ZnO, Sol-gel, x-ray diffraction
Procedia PDF Downloads 39616862 Modeling of Global Solar Radiation on a Horizontal Surface Using Artificial Neural Network: A Case Study
Authors: Laidi Maamar, Hanini Salah
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The present work investigates the potential of artificial neural network (ANN) model to predict the horizontal global solar radiation (HGSR). The ANN is developed and optimized using three years meteorological database from 2011 to 2013 available at the meteorological station of Blida (Blida 1 university, Algeria, Latitude 36.5°, Longitude 2.81° and 163 m above mean sea level). Optimal configuration of the ANN model has been determined by minimizing the Root Means Square Error (RMSE) and maximizing the correlation coefficient (R2) between observed and predicted data with the ANN model. To select the best ANN architecture, we have conducted several tests by using different combinations of parameters. A two-layer ANN model with six hidden neurons has been found as an optimal topology with (RMSE=4.036 W/m²) and (R²=0.999). A graphical user interface (GUI), was designed based on the best network structure and training algorithm, to enhance the users’ friendliness application of the model.Keywords: artificial neural network, global solar radiation, solar energy, prediction, Algeria
Procedia PDF Downloads 49816861 Checking Energy Efficiency by Simulation Tools: The Case of Algerian Ksourian Models
Authors: Khadidja Rahmani, Nahla Bouaziz
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Algeria is known for its rich heritage. It owns an immense historical heritage with a universal reputation. Unfortunately, this wealth is withered because of abundance. This research focuses on the Ksourian model, which constitutes a large portion of this wealth. In fact, the Ksourian model is not just a witness to a great part of history or a vernacular culture, but also it includes a panoply of assets in terms of energetic efficiency. In this context, the purpose of our work is to evaluate the performance of the old techniques which are derived from the Ksourian model , and that using the simulation tools. The proposed method is decomposed in two steps; the first consists of isolate and reintroduce each device into a basic model, then run a simulation series on acquired models. And this in order to test the contribution of each of these dialectal processes. In another scale of development, the second step consists of aggregating all these processes in an aboriginal model, then we restart the simulation, to see what it will give this mosaic on the environmental and energetic plan .The model chosen for this study is one of the ksar units of Knadsa city of Bechar (Algeria). This study does not only show the ingenuity of our ancestors in their know-how, and their adapting power to the aridity of the climate, but also proves that their conceptions subscribe in the current concerns of energy efficiency, and respond to the requirements of sustainable development.Keywords: dialectal processes, energy efficiency, evaluation, Ksourian model, simulation tools
Procedia PDF Downloads 19516860 Seismic Response of Moment Resisting Steel Frame with Hysteresis Envelope Model of Joints
Authors: Krolo Paulina
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The seismic response of moment-resisting steel frames depends on the behavior of the joints, especially when they are considered as ductile zones. The aim of this research is to provide a realistic assessment of the moment-resisting steel frame behavior under seismic loading using nonlinear static pushover analysis (N2 method). The hysteresis behavior of the joints in the frame model was described using a new hysteresis envelope model. The obtained seismic response was compared with the results of the seismic analysis obtained for the same steel frame that takes into account the monotonic model of the joints.Keywords: beam-to-column joints, hysteresis envelope model, moment-resisting frame, nonlinear static pushover analysis, N2 method
Procedia PDF Downloads 26516859 Models of Copyrights System
Authors: A. G. Matveev
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The copyrights system is a combination of different elements. The number, content and the correlation of these elements are different for different legal orders. The models of copyrights systems display this system in terms of the interaction of economic and author's moral rights. Monistic and dualistic models are the most popular ones. The article deals with different points of view on the monism and dualism in copyright system. A specific model of the copyright in Switzerland in the XXth century is analyzed. The evolution of a French dualistic model of copyright is shown. The author believes that one should talk not about one, but rather about a number of dualism forms of copyright system.Keywords: copyright, exclusive copyright, economic rights, author's moral rights, rights of personality, monistic model, dualistic model
Procedia PDF Downloads 42016858 Seismic Safety Evaluation of Weir Structures Using the Finite and Infinite Element Method
Authors: Ho Young Son, Bu Seog Ju, Woo Young Jung
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This study presents the seismic safety evaluation of weir structure subjected to strong earthquake ground motions, as a flood defense structure in civil engineering structures. The seismic safety analysis procedure was illustrated through development of Finite Element (FE) and InFinite Element (IFE) method in ABAQUS platform. The IFE model was generated by CINPS4, 4-node linear one-way infinite model as a sold continuum infinite element in foundation areas of the weir structure and then nonlinear FE model using friction model for soil-structure interactions was applied in this study. In order to understand the complex behavior of weir structures, nonlinear time history analysis was carried out. Consequently, it was interesting to note that the compressive stress gave more vulnerability to the weir structure, in comparison to the tensile stress, during an earthquake. The stress concentration of the weir structure was shown at the connection area between the weir body and stilling basin area. The stress both tension and compression was reduced in IFE model rather than FE model of weir structures.Keywords: seismic, numerical analysis, FEM, weir, boundary condition
Procedia PDF Downloads 45216857 Sliding Mode Controller for Active Suspension System on a Passenger Car Model
Authors: Nouby M. Ghazaly, Ahmed O. Moaaz, Mostafa Makrahy
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The main purpose of a car suspension system is to reduce the vibrations resulting from road roughness. The main objective of this research paper is to decrease vibration and improve passenger comfort through controlling car suspension system using sliding mode control techniques. The mathematical model for passive and active suspensions systems for quarter car model which subject to excitation from different road profiles is obtained. The active suspension system is synthesized based on sliding mode control for a quarter car model. The performance of the sliding mode control is determined through computer simulations using MATLAB and SIMULINK toolbox. The simulated results plotted in time domain, and root mean square values. It is found that active suspension system using sliding mode control improves the ride comfort and decrease vibration.Keywords: quarter car model, active suspension system, sliding mode control, road profile
Procedia PDF Downloads 30916856 Resolution and Experimental Validation of the Asymptotic Model of a Viscous Laminar Supersonic Flow around a Thin Airfoil
Authors: Eddegdag Nasser, Naamane Azzeddine, Radouani Mohammed, Ensam Meknes
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In this study, we are interested in the asymptotic modeling of the two-dimensional stationary supersonic flow of a viscous compressible fluid around wing airfoil. The aim of this article is to solve the partial differential equations of the flow far from the leading edge and near the wall using the triple-deck technique is what brought again in precision according to the principle of least degeneration. In order to validate our theoretical model, these obtained results will be compared with the experimental results. The comparison of the results of our model with experimentation has shown that they are quantitatively acceptable compared to the obtained experimental results. The experimental study was conducted using the AF300 supersonic wind tunnel and a NACA Reduced airfoil model with two pressure Taps on extrados. In this experiment, we have considered the incident upstream supersonic Mach number over a dissymmetric NACA airfoil wing. The validation and the accuracy of the results support our model.Keywords: supersonic, viscous, triple deck technique, asymptotic methods, AF300 supersonic wind tunnel, reduced airfoil model
Procedia PDF Downloads 24016855 Stability Analysis for an Extended Model of the Hypothalamus-Pituitary-Thyroid Axis
Authors: Beata Jackowska-Zduniak
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We formulate and analyze a mathematical model describing dynamics of the hypothalamus-pituitary-thyroid homoeostatic mechanism in endocrine system. We introduce to this system two types of couplings and delay. In our model, feedback controls the secretion of thyroid hormones and delay reflects time lags required for transportation of the hormones. The influence of delayed feedback on the stability behaviour of the system is discussed. Analytical results are illustrated by numerical examples of the model dynamics. This system of equations describes normal activity of the thyroid and also a couple of types of malfunctions (e.g. hyperthyroidism).Keywords: mathematical modeling, ordinary differential equations, endocrine system, delay differential equation
Procedia PDF Downloads 33616854 Safe and Efficient Deep Reinforcement Learning Control Model: A Hydroponics Case Study
Authors: Almutasim Billa A. Alanazi, Hal S. Tharp
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Safe performance and efficient energy consumption are essential factors for designing a control system. This paper presents a reinforcement learning (RL) model that can be applied to control applications to improve safety and reduce energy consumption. As hardware constraints and environmental disturbances are imprecise and unpredictable, conventional control methods may not always be effective in optimizing control designs. However, RL has demonstrated its value in several artificial intelligence (AI) applications, especially in the field of control systems. The proposed model intelligently monitors a system's success by observing the rewards from the environment, with positive rewards counting as a success when the controlled reference is within the desired operating zone. Thus, the model can determine whether the system is safe to continue operating based on the designer/user specifications, which can be adjusted as needed. Additionally, the controller keeps track of energy consumption to improve energy efficiency by enabling the idle mode when the controlled reference is within the desired operating zone, thus reducing the system energy consumption during the controlling operation. Water temperature control for a hydroponic system is taken as a case study for the RL model, adjusting the variance of disturbances to show the model’s robustness and efficiency. On average, the model showed safety improvement by up to 15% and energy efficiency improvements by 35%- 40% compared to a traditional RL model.Keywords: control system, hydroponics, machine learning, reinforcement learning
Procedia PDF Downloads 18516853 Prediction of Coronary Heart Disease Using Fuzzy Logic
Authors: Elda Maraj, Shkelqim Kuka
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Coronary heart disease causes many deaths in the world. Unfortunately, this problem will continue to increase in the future. In this paper, a fuzzy logic model to predict coronary heart disease is presented. This model has been developed with seven input variables and one output variable that was implemented for 30 patients in Albania. Here fuzzy logic toolbox of MATLAB is used. Fuzzy model inputs are considered as cholesterol, blood pressure, physical activity, age, BMI, smoking, and diabetes, whereas the output is the disease classification. The fuzzy sets and membership functions are chosen in an appropriate manner. Centroid method is used for defuzzification. The database is taken from University Hospital Center "Mother Teresa" in Tirana, Albania.Keywords: coronary heart disease, fuzzy logic toolbox, membership function, prediction model
Procedia PDF Downloads 16116852 A Boundary Fitted Nested Grid Model for Tsunami Computation along Penang Island in Peninsular Malaysia
Authors: Md. Fazlul Karim, Ahmad Izani Md. Ismail, Mohammed Ashaque Meah
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This paper focuses on the development of a 2-D Boundary Fitted and Nested Grid (BFNG) model to compute the tsunami propagation of Indonesian tsunami 2004 along the coastal region of Penang in Peninsular Malaysia. In the presence of a curvilinear coastline, boundary fitted grids are suitable to represent the model boundaries accurately. On the other hand, when large gradient of velocity within a confined area is expected, the use of a nested grid system is appropriate to improve the numerical accuracy with the least grid numbers. This paper constructs a shallow water nested and orthogonal boundary fitted grid model and presents computational results of the tsunami impact on the Penang coast due to the Indonesian tsunami of 2004. The results of the numerical simulations are compared with available data.Keywords: boundary fitted nested model, tsunami, Penang Island, 2004 Indonesian Tsunami
Procedia PDF Downloads 32316851 The Status of BIM Adoption in Six Continents
Authors: Wooyoung Jung, Ghang Lee
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This paper paper reports the worldwide status of building information modeling (BIM) adoption from the perspectives of the engagement level, the Hype Cycle model, the technology diffusion model, and BIM-uses. An online survey was distributed, and 156 experts from six continents responded. Overall, North America was the most advanced continent, followed by Oceania and Europe. Countries in Asia perceived their phase mainly as slope of enlightenment (mature) in the Hype Cycle model. In the technology diffusion model, the main BIM-users worldwide were “early majority” (third phase), but those in the Middle East/Africa and South America were “early adopters” (second phase). In addition, the more advanced the country, the more number of BIM services employed in general. In summary, North America, Europe, Oceania, and Asia were advancing rapidly toward the mature stage of BIM, whereas the Middle East/Africa and South America were still in the early phase. The simple indexes used in this study may be used to track the worldwide status of BIM adoption in long-term surveys.Keywords: BIM adoption, BIM services, hype cycle model, technology diffusion model
Procedia PDF Downloads 55716850 A Model to Assist Military Mission Planners in Identifying and Assessing Variables Impacting Food Security
Authors: Lynndee Kemmet
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The U.S. military plays an increasing role in supporting political stability efforts, and this includes efforts to prevent the food insecurity that can trigger political and social instability. This paper presents a model that assists military commanders in identifying variables that impact food production and distribution in their areas of operation (AO), in identifying connections between variables and in assessing the impacts of those variables on food production and distribution. Through use of the model, military units can better target their data collection efforts and can categorize and analyze data within the data categorization framework most widely-used by military forces—PMESII-PT (Political, Military, Economic, Infrastructure, Information, Physical Environment and Time). The model provides flexibility of analysis in that commanders can target analysis to be highly focused on a specific PMESII-PT domain or variable or conduct analysis across multiple PMESII-PT domains. The model is also designed to assist commanders in mapping food systems in their AOs and then identifying components of those systems that must be strengthened or protected.Keywords: food security, food system model, political stability, US Military
Procedia PDF Downloads 19516849 New Segmentation of Piecewise Moving-Average Model by Using Reversible Jump MCMC Algorithm
Authors: Suparman
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This paper addresses the problem of the signal segmentation within a Bayesian framework by using reversible jump MCMC algorithm. The signal is modelled by piecewise constant Moving-Average (MA) model where the numbers of segments, the position of change-point, the order and the coefficient of the MA model for each segment are unknown. The reversible jump MCMC algorithm is then used to generate samples distributed according to the joint posterior distribution of the unknown parameters. These samples allow calculating some interesting features of the posterior distribution. The performance of the methodology is illustrated via several simulation results.Keywords: piecewise, moving-average model, reversible jump MCMC, signal segmentation
Procedia PDF Downloads 22716848 A Study on Automotive Attack Database and Data Flow Diagram for Concretization of HEAVENS: A Car Security Model
Authors: Se-Han Lee, Kwang-Woo Go, Gwang-Hyun Ahn, Hee-Sung Park, Cheol-Kyu Han, Jun-Bo Shim, Geun-Chul Kang, Hyun-Jung Lee
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In recent years, with the advent of smart cars and the expansion of the market, the announcement of 'Adventures in Automotive Networks and Control Units' at the DEFCON21 conference in 2013 revealed that cars are not safe from hacking. As a result, the HEAVENS model considering not only the functional safety of the vehicle but also the security has been suggested. However, the HEAVENS model only presents a simple process, and there are no detailed procedures and activities for each process, making it difficult to apply it to the actual vehicle security vulnerability check. In this paper, we propose an automated attack database that systematically summarizes attack vectors, attack types, and vulnerable vehicle models to prepare for various car hacking attacks, and data flow diagrams that can detect various vulnerabilities and suggest a way to materialize the HEAVENS model.Keywords: automotive security, HEAVENS, car hacking, security model, information security
Procedia PDF Downloads 36216847 A TgCNN-Based Surrogate Model for Subsurface Oil-Water Phase Flow under Multi-Well Conditions
Authors: Jian Li
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The uncertainty quantification and inversion problems of subsurface oil-water phase flow usually require extensive repeated forward calculations for new runs with changed conditions. To reduce the computational time, various forms of surrogate models have been built. Related research shows that deep learning has emerged as an effective surrogate model, while most surrogate models with deep learning are purely data-driven, which always leads to poor robustness and abnormal results. To guarantee the model more consistent with the physical laws, a coupled theory-guided convolutional neural network (TgCNN) based surrogate model is built to facilitate computation efficiency under the premise of satisfactory accuracy. The model is a convolutional neural network based on multi-well reservoir simulation. The core notion of this proposed method is to bridge two separate blocks on top of an overall network. They underlie the TgCNN model in a coupled form, which reflects the coupling nature of pressure and water saturation in the two-phase flow equation. The model is driven by not only labeled data but also scientific theories, including governing equations, stochastic parameterization, boundary, and initial conditions, well conditions, and expert knowledge. The results show that the TgCNN-based surrogate model exhibits satisfactory accuracy and efficiency in subsurface oil-water phase flow under multi-well conditions.Keywords: coupled theory-guided convolutional neural network, multi-well conditions, surrogate model, subsurface oil-water phase
Procedia PDF Downloads 8616846 Applicability of Linearized Model of Synchronous Generator for Power System Stability Analysis
Authors: J. Ritonja, B. Grcar
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For the synchronous generator simulation and analysis and for the power system stabilizer design and synthesis a mathematical model of synchronous generator is needed. The model has to accurately describe dynamics of oscillations, while at the same time has to be transparent enough for an analysis and sufficiently simplified for design of control system. To study the oscillations of the synchronous generator against to the rest of the power system, the model of the synchronous machine connected to an infinite bus through a transmission line having resistance and inductance is needed. In this paper, the linearized reduced order dynamic model of the synchronous generator connected to the infinite bus is presented and analysed in details. This model accurately describes dynamics of the synchronous generator only in a small vicinity of an equilibrium state. With the digression from the selected equilibrium point the accuracy of this model is decreasing considerably. In this paper, the equations’ descriptions and the parameters’ determinations for the linearized reduced order mathematical model of the synchronous generator are explained and summarized and represent the useful origin for works in the areas of synchronous generators’ dynamic behaviour analysis and synchronous generator’s control systems design and synthesis. The main contribution of this paper represents the detailed analysis of the accuracy of the linearized reduced order dynamic model in the entire synchronous generator’s operating range. Borders of the areas where the linearized reduced order mathematical model represents accurate description of the synchronous generator’s dynamics are determined with the systemic numerical analysis. The thorough eigenvalue analysis of the linearized models in the entire operating range is performed. In the paper, the parameters of the linearized reduced order dynamic model of the laboratory salient poles synchronous generator were determined and used for the analysis. The theoretical conclusions were confirmed with the agreement of experimental and simulation results.Keywords: eigenvalue analysis, mathematical model, power system stability, synchronous generator
Procedia PDF Downloads 24516845 Diesel Fault Prediction Based on Optimized Gray Neural Network
Authors: Han Bing, Yin Zhenjie
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In order to analyze the status of a diesel engine, as well as conduct fault prediction, a new prediction model based on a gray system is proposed in this paper, which takes advantage of the neural network and the genetic algorithm. The proposed GBPGA prediction model builds on the GM (1.5) model and uses a neural network, which is optimized by a genetic algorithm to construct the error compensator. We verify our proposed model on the diesel faulty simulation data and the experimental results show that GBPGA has the potential to employ fault prediction on diesel.Keywords: fault prediction, neural network, GM(1, 5) genetic algorithm, GBPGA
Procedia PDF Downloads 30416844 Further Investigation of α+12C and α+16O Elastic Scattering
Authors: Sh. Hamada
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The current work aims to study the rainbow like-structure observed in the elastic scattering of alpha particles on both 12C and 16O nuclei. We reanalyzed the experimental elastic scattering angular distributions data for α+12C and α+16O nuclear systems at different energies using both optical model and double folding potential of different interaction models such as: CDM3Y1, DDM3Y1, CDM3Y6 and BDM3Y1. Potential created by BDM3Y1 interaction model has the shallowest depth which reflects the necessity to use higher renormalization factor (Nr). Both optical model and double folding potential of different interaction models fairly reproduce the experimental data.Keywords: density distribution, double folding, elastic scattering, nuclear rainbow, optical model
Procedia PDF Downloads 23716843 Computational Model of Human Cardiopulmonary System
Authors: Julian Thrash, Douglas Folk, Michael Ciracy, Audrey C. Tseng, Kristen M. Stromsodt, Amber Younggren, Christopher Maciolek
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The cardiopulmonary system is comprised of the heart, lungs, and many dynamic feedback mechanisms that control its function based on a multitude of variables. The next generation of cardiopulmonary medical devices will involve adaptive control and smart pacing techniques. However, testing these smart devices on living systems may be unethical and exceedingly expensive. As a solution, a comprehensive computational model of the cardiopulmonary system was implemented in Simulink. The model contains over 240 state variables and over 100 equations previously described in a series of published articles. Simulink was chosen because of its ease of introducing machine learning elements. Initial results indicate that physiologically correct waveforms of pressures and volumes were obtained in the simulation. With the development of a comprehensive computational model, we hope to pioneer the future of predictive medicine by applying our research towards the initial stages of smart devices. After validation, we will introduce and train reinforcement learning agents using the cardiopulmonary model to assist in adaptive control system design. With our cardiopulmonary model, we will accelerate the design and testing of smart and adaptive medical devices to better serve those with cardiovascular disease.Keywords: adaptive control, cardiopulmonary, computational model, machine learning, predictive medicine
Procedia PDF Downloads 17916842 Functional Instruction Set Simulator (ISS) of a Neural Network (NN) IP with Native BF-16 Generator
Authors: Debajyoti Mukherjee, Arathy B. S., Arpita Sahu, Saranga P. Pogula
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A Functional Model to mimic the functional correctness of a Neural Network Compute Accelerator IP is very crucial for design validation. Neural network workloads are based on a Brain Floating Point (BF-16) data type. The major challenge we were facing was the incompatibility of gcc compilers to BF-16 datatype, which we addressed with a native BF-16 generator integrated to our functional model. Moreover, working with big GEMM (General Matrix Multiplication) or SpMM (Sparse Matrix Multiplication) Work Loads (Dense or Sparse) and debugging the failures related to data integrity is highly painstaking. In this paper, we are addressing the quality challenge of such a complex Neural Network Accelerator design by proposing a Functional Model-based scoreboard or Software model using SystemC. The proposed Functional Model executes the assembly code based on the ISA of the processor IP, decodes all instructions, and executes as expected to be done by the DUT. The said model would give a lot of visibility and debug capability in the DUT bringing up micro-steps of execution.Keywords: ISA (instruction set architecture), NN (neural network), TLM (transaction-level modeling), GEMM (general matrix multiplication)
Procedia PDF Downloads 8616841 Non-Cytotoxic Natural Sourced Inorganic Hydroxyapatite (HAp) Scaffold Facilitate Bone-like Mechanical Support and Cell Proliferation
Authors: Sudip Mondal, Biswanath Mondal, Sudit S. Mukhopadhyay, Apurba Dey
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Bioactive materials improve devices for a long lifespan but have mechanical limitations. Mechanical characterization is one of the very important characteristics to evaluate the life span and functionality of the scaffold material. After implantation of scaffold material the primary stage rejection of scaffold occurs due to non biocompatible effect of host body system. The second major problems occur due to the effect of mechanical failure. The mechanical and biocompatibility failure of the scaffold materials can be overcome by the prior evaluation of the scaffold materials. In this study chemically treated Labeo rohita scale is used for synthesizing hydroxyapatite (HAp) biomaterial. Thermo-gravimetric and differential thermal analysis (TG-DTA) is carried out to ensure thermal stability. The chemical composition and bond structures of wet ball-milled calcined HAp powder is characterized by Fourier Transform Infrared spectroscopy (FTIR), X-ray Diffraction (XRD), Field Emission Scanning Electron Microscopy (FE-SEM), Transmission Electron Microscopy (TEM), Energy Dispersive X-ray (EDX) analysis. Fish scale derived apatite materials consists of nano-sized particles with Ca/P ratio of 1.71. The biocompatibility through cytotoxicity evaluation and MTT assay are carried out in MG63 osteoblast cell lines. In the cell attachment study, the cells are tightly attached with HAp scaffolds developed in the laboratory. The result clearly suggests that HAp material synthesized in this study do not have any cytotoxic effect, as well as it has a natural binding affinity for mammalian cell lines. The synthesized HAp powder further successfully used to develop porous scaffold material with suitable mechanical property of ~0.8GPa compressive stress, ~1.10 GPa a hardness and ~ 30-35% porosity which is acceptable for implantation in trauma region for animal model. The histological analysis also supports the bio-affinity of processed HAp biomaterials in Wistar rat model for investigating the contact reaction and stability at the artificial or natural prosthesis interface for biomedical function. This study suggests the natural sourced fish scale-derived HAp material could be used as a suitable alternative biomaterial for tissue engineering application in near future.Keywords: biomaterials, hydroxyapatite, scaffold, mechanical property, tissue engineering
Procedia PDF Downloads 45516840 Sol-Gel Derived ZnO Nanostructures: Optical Properties
Authors: Sheo K. Mishra, Rajneesh K. Srivastava, R. K. Shukla
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In the present work, we report on the optical properties including UV-vis absorption and photoluminescence (PL) of ZnO nanostructures synthesized by sol-gel method. Structural and morphological investigations have been performed by X-ray diffraction method (XRD) and scanning electron microscopy (SEM). The XRD result confirms the formation of hexagonal wurtzite phase of ZnO nanostructures. The presence of various diffraction peaks suggests polycrystalline nature. The XRD pattern exhibits no additional peak due to by-products such as Zn(OH)2. The average crystallite size of prepared ZnO sample corresponding to the maximum intensity peaks is to be ~38.22 nm. The SEM micrograph shows different nanostructures of pure ZnO. Photoluminescence (PL) spectrum shows several emission peaks around 353 nm, 382 nm, 419 nm, 441 nm, 483 nm and 522 nm. The obtained results suggest that the prepared phosphors are quite suitable for optoelectronic applications.Keywords: ZnO, sol-gel, XRD, PL
Procedia PDF Downloads 40016839 End-to-End Spanish-English Sequence Learning Translation Model
Authors: Vidhu Mitha Goutham, Ruma Mukherjee
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The low availability of well-trained, unlimited, dynamic-access models for specific languages makes it hard for corporate users to adopt quick translation techniques and incorporate them into product solutions. As translation tasks increasingly require a dynamic sequence learning curve; stable, cost-free opensource models are scarce. We survey and compare current translation techniques and propose a modified sequence to sequence model repurposed with attention techniques. Sequence learning using an encoder-decoder model is now paving the path for higher precision levels in translation. Using a Convolutional Neural Network (CNN) encoder and a Recurrent Neural Network (RNN) decoder background, we use Fairseq tools to produce an end-to-end bilingually trained Spanish-English machine translation model including source language detection. We acquire competitive results using a duo-lingo-corpus trained model to provide for prospective, ready-made plug-in use for compound sentences and document translations. Our model serves a decent system for large, organizational data translation needs. While acknowledging its shortcomings and future scope, it also identifies itself as a well-optimized deep neural network model and solution.Keywords: attention, encoder-decoder, Fairseq, Seq2Seq, Spanish, translation
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