Search results for: 3D magnetic potential vector and electric scalar potential (A
13573 Energy Consumption and Energy Conservation Potential for HVAC System in Commercial Buildings Sector in India
Authors: Rishabh Agrawal, S. C. Kaushik, T. S. Bhatti
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In order to reduce energy consumption for sustainable development, continuous energy consumption tracking of building energy systems are essential. In this paper an assessment study has been done to identify the energy consumption & energy conservation potential for commercial buildings sector in Karnataka state, India. There are a total of 326 commercial buildings in the state of Karnataka who has qualified as designated consumers (i.e., having a Contract Demand ≥ 600 KVA), was consider for the study. It has estimated that the annual electricity sale to commercial sector is 3.62 Billion Units (BU) in alone Karnataka State, India, which is an account for 9.57 % of the total electricity sold. The commercial sector constitutes Government & private establishments, hospitals, hotels, restaurants, educational institutions, malls etc. Total 326 commercial buildings in the state accounting for annual energy consumption of 1295.72 Million Units (MU) which works out to about 35% of the sectoral consumption. The annual energy savings potential for 326 commercial buildings is assessed to be 0.25 BU.Keywords: commercial buildings, connected load, energy conservation studies, energy savings, energy efficiency, energy conservation strategy, energy efficiency, thermal energy, HVAC system
Procedia PDF Downloads 58013572 MRI Compatible Fresnel Zone Plates made of Polylactic Acid
Authors: Daniel Tarrazó-Serrano, Sergio Pérez-López, Sergio Castiñeira-Ibáñez, Pilar Candelas, Constanza Rubio
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Zone Plates (ZPs) are used in many areas of physics where planar fabrication is advantageous in comparison with conventional curved lenses. There are several types of ZPs, such as the well-known Fresnel ZPs or the more recent Fractal ZPs and Fibonacci ZPs. The material selection of the lens plays a very important role in the beam modulation control. This work presents a comparison between two Fresnel ZP made from different materials in the ultrasound domain: Polylactic Acid (PLA) and brass. PLA is the most common material used in commercial 3D-printers due to its high design flexibility and low cost. Numerical simulations based on Finite Element Method (FEM) and experimental results are shown, and they prove that the focusing capabilities of brass ZPs and PLA ZPs are similar. For this reason, PLA is proposed as a Magnetic Resonance Imaging (MRI) compatible material with great potential for therapeutic ultrasound focusing applications.Keywords: FZP, PLA, focus, ultrasound, MRI
Procedia PDF Downloads 20413571 Assessment of Exposure Dose Rate from Scattered X-Radiation during Diagnostic Examination in Nigerian University Teaching Hospital
Authors: Martins Gbenga., Orosun M. M., Olowookere C. J., Bamidele Lateef
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Radiation exposures from diagnostic medical examinations are almost always justified by the benefits of accurate diagnosis of possible disease conditions. The aim is to assess the influence of selected exposure parameters on scattered dose rates. The research was carried out using Gamma Scout software installation on the Computer system (Laptop) to record the radiation counts, pulse rate, and dose rate for 136 patients. Seventy-three patients participated in the male category with 53.7%, while 63 females participated with 46.3%. The mean and standard deviation value for each parameter is recorded, and tube potential is within 69.50±11.75 ranges between 52.00 and 100.00, tube current is within 23.20±17.55 ranges between 4.00 and 100.00, focus skin distance is within 73.195±33.99 and ranges between 52.00 and 100.00. Dose Rate (DRate in µSv/hr) is significant at an interval of 0.582 and 0.587 for tube potential and body thickness (cm). Tube potential is significant at an interval of 0.582 and 0.842 of DRate (µSv/hr) and body thickness (cm). The study was compared with other studies. The exposure parameters selected during each examination contributed to scattered radiation. A quality assurance program (QAP) is advised for the center.Keywords: x-radiation, exposure rate, dose rate, tube potentials, scattered radiation, diagnostic examination
Procedia PDF Downloads 14513570 Deep Groundwater Potential and Chemical Analysis Based on Well Logging Analysis at Kapuk-Cengkareng, West Jakarta, DKI Jakarta, Indonesia
Authors: Josua Sihotang
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Jakarta Capital Special Region is the province that densely populated with rapidly growing infrastructure but less attention for the environmental condition. This makes some social problem happened like lack of clean water supply. Shallow groundwater and river water condition that has contaminated make the layer of deep water carrier (aquifer) should be done. This research aims to provide the people insight about deep groundwater potential and to determine the depth, location, and quality where the aquifer can be found in Jakarta’s area, particularly Kapuk-Cengkareng’s people. This research was conducted by geophysical method namely Well Logging Analysis. Well Logging is the geophysical method to know the subsurface lithology with the physical characteristic. The observation in this research area was conducted with several well devices that is Spontaneous Potential Log (SP Log), Resistivity Log, and Gamma Ray Log (GR Log). The first devices well is SP log which is work by comprising the electrical potential difference between the electrodes on the surface with the electrodes that is contained in the borehole and rock formations. The second is Resistivity Log, used to determine both the hydrocarbon and water zone based on their porosity and permeability properties. The last is GR Log, work by identifying radioactivity levels of rocks which is containing elements of thorium, uranium, or potassium. The observation result is curve-shaped which describes the type of lithological coating in subsurface. The result from the research can be interpreted that there are four of the deep groundwater layer zone with different quality. The good groundwater layer can be found in layers with good porosity and permeability. By analyzing the curves, it can be known that most of the layers which were found in this wellbore are clay stone with low resistivity and high gamma radiation. The resistivity value of the clay stone layers is about 2-4 ohm-meter with 65-80 Cps gamma radiation. There are several layers with high resistivity value and low gamma radiation (sand stone) that can be potential for being an aquifer. This is reinforced by the sand layer with a right-leaning SP log curve proving that this layer is permeable. These layers have 4-9 ohm-meter resistivity value with 40-65 Cps gamma radiation. These are mostly found as fresh water aquifer.Keywords: aquifer, deep groundwater potential, well devices, well logging analysis
Procedia PDF Downloads 25213569 Exploring the Potential of Replika: An AI Chatbot for Mental Health Support
Authors: Nashwah Alnajjar
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This research paper provides an overview of Replika, an AI chatbot application that uses natural language processing technology to engage in conversations with users. The app was developed to provide users with a virtual AI friend who can converse with them on various topics, including mental health. This study explores the experiences of Replika users using quantitative research methodology. A survey was conducted with 12 participants to collect data on their demographics, usage patterns, and experiences with the Replika app. The results showed that Replika has the potential to play a role in mental health support and well-being.Keywords: Replika, chatbot, mental health, artificial intelligence, natural language processing
Procedia PDF Downloads 8613568 Privacy Concerns and Law Enforcement Data Collection to Tackle Domestic and Sexual Violence
Authors: Francesca Radice
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Domestic and sexual violence provokes, on average in Australia, one female death per week due to intimate violence behaviours. 83% of couples meet online, and intercepting domestic and sexual violence at this level would be beneficial. It has been observed that violent or coercive behaviour has been apparent from initial conversations on dating apps like Tinder. Child pornography, stalking, and coercive control are some criminal offences from dating apps, including women murdered after finding partners through Tinder. Police databases and predictive policing are novel approaches taken to prevent crime before harm is done. This research will investigate how police databases can be used in a privacy-preserving way to characterise users in terms of their potential for violent crime. Using the COPS database of NSW Police, we will explore how the past criminal record can be interpreted to yield a category of potential danger for each dating app user. It is up to the judgement of each subscriber on what degree of the potential danger they are prepared to enter into. Sentiment analysis is an area where research into natural language processing has made great progress over the last decade. This research will investigate how sentiment analysis can be used to interpret interchanges between dating app users to detect manipulative or coercive sentiments. These can be used to alert law enforcement if continued for a defined number of communications. One of the potential problems of this approach is the potential prejudice a categorisation can cause. Another drawback is the possibility of misinterpreting communications and involving law enforcement without reason. The approach will be thoroughly tested with cross-checks by human readers who verify both the level of danger predicted by the interpretation of the criminal record and the sentiment detected from personal messages. Even if only a few violent crimes can be prevented, the approach will have a tangible value for real people.Keywords: sentiment analysis, data mining, predictive policing, virtual manipulation
Procedia PDF Downloads 7813567 Structural, Magnetic, Electrical and Dielectric Properties of Pr0.8Na0.2MnO3 Manganite
Authors: H. Ben Khlifa, W. Cheikhrouhou, R. M'nassri
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The Orthorhombic Pr0.8Na0.2MnO3 ceramic was prepared in Polycrystalline form by a Pechini sol–gel method and its structural, magnetic, electrical, and dielectric properties were investigated experimentally. A structural study confirms that the sample is a single phase. Magnetic measurements show that the sample is a charge ordered Manganite. The sample undergoes two successive magnetic phase transitions with the variation of temperature: a charge ordering transition occurred at TCO = 212 K followed by a Paramagnetic (PM) to ferromagnetic (FM) transition around TC = 115 K. From an electrical point of view, a saturation region was marked in the conductivity as a function of Temperature s(T) curves at a specific temperature. The dc-conductivity (sdc) reaches a maximum value at 240 K. The obtained results are in good agreement with the temperature dependence of the average normalized change (ANC). We found that the conduction mechanism was governed by small polaron hopping (SPH) in the high-temperature region and by variable range hopping (VRH) in the low-temperature region. Complex impedance analysis indicates the presence of a non-Debye relaxation phenomenon in the system. Also, the compound was modeled by an electrical equivalent circuit. Then, the contribution of the grain boundary in the transport properties was confirmed.Keywords: manganites, preparation methods, magnetization, magnetocaloric effect, electrical and dielectric
Procedia PDF Downloads 17313566 Synergistic Effect between Titanium Oxide and Silver Nanoparticles in Polymeric Binary Systems
Authors: Raquel C. A. G. Mota, Livia R. Menezes, Emerson O. da Silva
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Both silver nanoparticles and titanium dioxide have been extensively used in tissue engineering since they’ve been approved by the Food and Drug Administration (FDA), and present a bactericide effect when added to a polymeric matrix. In this work, the focus is on fabricating binary systems with both nanoparticles so that the synergistic effect can be investigated. The systems were tested by Nuclear Magnetic Resonance (NMR), Thermogravimetric Analysis (TGA), Fourier-Transformed Infrared (FTIR), and Differential Scanning Calorimetry (DSC), and X-ray Diffraction (XRD), and had both their bioactivity and bactericide effect tested. The binary systems presented different properties than the individual systems, enhancing both the thermal and biological properties as was to be expected. The crystallinity was also affected, as indicated by the finding of the DSC and XDR techniques, and the NMR showed a good dispersion of both nanoparticles in the polymer matrix. These findings indicate the potential of combining TiO₂ and silver nanoparticles in biomedicine.Keywords: metallic nanoparticles, nanotechnology, polymer nanocomposites, polymer science
Procedia PDF Downloads 13413565 Opportunities for Effective Conflict Management Caused by Global Crises
Authors: Marine Kobalava
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The article analyzes current global crises in the world, explains the causes of crises, substantiates that in the main cases the process accompanying the crisis are conflict situations. The paper argues that crises can become predictable if threats are identified and addressed by a company, organization, corporation, and others. Accordingly, mechanisms for the neutralization of conflict potential are proposed, the need to develop a communication strategy and create and redistribute information flows is justified. Conflict situations are assessed according to the types of crisis and it is considered that the conflict can become a prerequisite for the crisis. The paper substantiates the need to differentiate theories of crises and conflicts. Based on the evaluative judgment, conflict management measures are proposed taking into account institutionalization, conflict resolution norms and rules. The paper identifies the potential for conflicts created in the context of global crises and suggests local ways and mechanisms for their effective management. The involvement of the company's Public relations (PR) and relevant communication from the qualified staff is considered important. Conclusions are drawn on the problems of effective conflict management caused by global crises and recommendations for conflict resolution have been proposed.Keywords: global crises, conflict situations, conflict identification, conflict management, conflict potential
Procedia PDF Downloads 13813564 Stability and Rheological Study of Carbon Nanotube Water Based Nanofluid
Authors: S. Rashidi, L. C. Abdullah, R. Walvekar, K. Mohammad, F-R. Ahmadun, M. Y. Faizah
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In this research, stability and rheology behavior of Multi-walled carbon nanotube (MWCNT) nanofluids by using Xanthan Gum as a dispersant were measured. This paper addresses the effects of Xanthan Gum (XG) concentration and nanoparticle loading on stability and viscosity of nanofluids. The stability of nanofluids is measured by Zeta Sizer Nano-ZS (Malvern Instruments, ZEN 3600). The zeta potential of the stable samples was analyzed. The rheological behavior of carbon nanotube CNT nanofluids was analyzed using rheometer (Model AR G2, TA Instrument). Both stability and viscosity of the nanofluids increased with increasing CNT and XG concentration. The experimental results indicated that the zeta potential of nanofluid samples is stable. The results demonstrated that the zeta potential was affected by the CNT concentration and is augmented in parallel with increasing CNT concentration. The rheology results showed that the viscosity of CNT/XG nanofluid was increased. The escalated viscosity of CNT/XG nanofluid is owing to the higher van der Waals interaction between the CNT nanoparticles. On the other hand, the viscosity of the CNT/XG nanofluid decreases with increasing temperature. In summary, this research provides useful insight into the behavior of CNT nanofluids.Keywords: nanofluid, carbon nanotube, stability, rheology
Procedia PDF Downloads 13213563 Design and Control Algorithms for Power Electronic Converters for EV Applications
Authors: Ilya Kavalchuk, Mehdi Seyedmahmoudian, Ben Horan, Aman Than Oo, Alex Stojcevski
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The power electronic components within Electric Vehicles (EV) need to operate in several important modes. Some modes directly influence safety, while others influence vehicle performance. Given the variety of functions and operational modes required of the power electronics, it needs to meet efficiency requirements to minimize power losses. Another challenge in the control and construction of such systems is the ability to support bidirectional power flow. This paper considers the construction, operation, and feasibility of available converters for electric vehicles with feasible configurations of electrical buses and loads. This paper describes logic and control signals for the converters for different operations conditions based on the efficiency and energy usage bases.Keywords: electric vehicles, electrical machines control, power electronics, powerflow regulations
Procedia PDF Downloads 55913562 Stern-Gerlach Force in Quantum Magnetic Field and Schrodinger's Cat
Authors: Mandip Singh
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Quantum entanglement plays a fundamental role in our understanding of counter-intuitive aspects of quantum reality. If classical physics is an approximation of quantum physics, then quantum entanglement should persist at a macroscopic scale. In this paper, a thought experiment is presented where a free falling spin polarized Bose-Einstein condensate interacts with a quantum superimposed magnetic field of nonzero gradient. In contrast to the semiclassical Stern-Gerlach experiment, the magnetic field and the spin degrees of freedom both are considered to be quantum mechanical in a generalized scenario. As a consequence, a Bose-Einstein condensate can be prepared at distinct locations in space in a sense of quantum superposition. In addition, the generation of Schrodinger-cat like quantum states shall be presented.Keywords: Schrodinger-cat quantum states, macroscopic entanglement, macroscopic quantum fields, foundations of quantum physics
Procedia PDF Downloads 18913561 Automatic Seizure Detection Using Weighted Permutation Entropy and Support Vector Machine
Authors: Noha Seddik, Sherine Youssef, Mohamed Kholeif
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The automated epileptic seizure detection research field has emerged in the recent years; this involves analyzing the Electroencephalogram (EEG) signals instead of the traditional visual inspection performed by expert neurologists. In this study, a Support Vector Machine (SVM) that uses Weighted Permutation Entropy (WPE) as the input feature is proposed for classifying normal and seizure EEG records. WPE is a modified statistical parameter of the permutation entropy (PE) that measures the complexity and irregularity of a time series. It incorporates both the mapped ordinal pattern of the time series and the information contained in the amplitude of its sample points. The proposed system utilizes the fact that entropy based measures for the EEG segments during epileptic seizure are lower than in normal EEG.Keywords: electroencephalogram (EEG), epileptic seizure detection, weighted permutation entropy (WPE), support vector machine (SVM)
Procedia PDF Downloads 37013560 Determination of the Axial-Vector from an Extended Linear Sigma Model
Authors: Tarek Sayed Taha Ali
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The dependence of the axial-vector coupling constant gA on the quark masses has been investigated in the frame work of the extended linear sigma model. The field equations have been solved in the mean-field approximation. Our study shows a better fitting to the experimental data compared with the existing models.Keywords: extended linear sigma model, nucleon properties, axial coupling constant, physic
Procedia PDF Downloads 44513559 Combined Treatment of PARP-1 Inhibitor and Carbon Ion or Gamma Exposure Reduces the Metastatic Potential in Cultured Human Cells
Authors: Priyanka Chowdhury, Asitikantha Sarma, Utpal Ghosh
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Hadron therapy using high Linear Energy Transfer (LET) ion beam is producing promising clinical results worldwide. The major advantages are its ability to kill radio-resistant tumor and its anti-metastatic activity. Poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors have been widely used as radiosensitizer, but its role in metastasis is unknown. The purpose of our study was to investigate the effect of PARP-1 depletion in combination with either Carbon Ion Beam (CIB) or gamma irradiation on metastatic potential of cultured cancerous cells. A549 cells were irradiated with CIB (0-4Gy) or gamma (0, 2, 4, 6 and 10 Gy) with and without PARP-1 inhibition. The metastatic potential of the cells was determined by cell migratory assay, expression, and activity of MMP-2 and MMP-9, expression of Cadherin, Fibronectin, and Vimentin. CIB exposure reduced migratory property and activity of MMP-2 and MMP-9 significantly. CIB with PARP-1 inhibition reduced cell migration and Matrix Metalloproteinase (MMPs) activity in a synergistic manner. Expression of MMPs was also down-regulated in CIB and combined treatment. On the contrary, MMP- 2 and MMP-9 activity was significantly increased in gamma irradiated cells but decreased upon combined treatment of gamma and PARP-1 inhibitor. MMPs expression and migration was reduced when gamma irradiation was combined with PARP-1 inhibition. Thus, our study clearly demonstrates that PARP-1 inhibition in combination with either high or low LET can significantly suppress metastatic potential in cancer cells and thereby can be a promising tool in controlling metastatic cancers.Keywords: high LET, low LET, matrix metalloproteinase (MMP), PARP-1
Procedia PDF Downloads 21413558 Surprising Behaviour of Kaolinitic Soils under Alkaline Environment
Authors: P. Hari Prasad Reddy, Shimna Paulose, V. Sai Kumar, C. H. Rama Vara Prasad
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Soil environment gets contaminated due to rapid industrialisation, agricultural-chemical application and improper disposal of waste generated by the society. Unexpected volume changes can occur in soil in the presence of certain contaminants usually after the long duration of interaction. Alkali is one of the major soil contaminant that has a considerable effect on behaviour of soils and capable of inducing swelling potential in soil. Chemical heaving of clayey soils occurs when they are wetted by aqueous solutions of alkalis. Mineralogical composition of the soil is one of the main factors influencing soil- alkali interaction. In the present work, studies are carried out to understand the swell potential of soils due to soil-alkali interaction with different concentrations of NaOH solution. Locally available soil, namely, red earth containing kaolinite which is of non-swelling nature is selected for the study. In addition to this, two commercially available clayey soils, namely ball clay and china clay containing mainly of kaolinite are selected to understand the effect of alkali interaction in various kaolinitic soils. Non-swelling red earth shows maximum swell at lower concentrations of alkali solution (0.1N) and a slightly decreasing trend of swelling with further increase in concentration (1N, 4N, and 8N). Marginal decrease in swell potential with increase in concentration indicates that the increased concentration of alkali solution exists as free solution in case of red earth. China clay and ball clay both falling under kaolinite group of clay minerals, show swelling with alkaline solution. At lower concentrations of alkali solution both the soils shows similar swell behaviour, but at higher concentration of alkali solution ball clay shows high swell potential compared to china clay which may be due to lack of well ordered crystallinity in ball clay compared to china clay. The variations in the results obtained were corroborated by carrying XRD and SEM studies.Keywords: alkali, kaolinite, swell potential, XRD, SEM
Procedia PDF Downloads 50213557 Possibilities to Evaluate the Climatic and Meteorological Potential for Viticulture in Poland: The Case Study of the Jagiellonian University Vineyard
Authors: Oskar Sekowski
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Current global warming causes changes in the traditional zones of viticulture worldwide. During 20th century, the average global air temperature increased by 0.89˚C. The models of climate change indicate that viticulture, currently concentrating in narrow geographic niches, may move towards the poles, to higher geographic latitudes. Global warming may cause changes in traditional viticulture regions. Therefore, there is a need to estimate the climatic conditions and climate change in areas that are not traditionally associated with viticulture, e.g., Poland. The primary objective of this paper is to prepare methodology to evaluate the climatic and meteorological potential for viticulture in Poland based on a case study. Moreover, the additional aim is to evaluate the climatic potential of a mesoregion where a university vineyard is located. The daily data of temperature, precipitation, insolation, and wind speed (1988-2018) from the meteorological station located in Łazy, southern Poland, was used to evaluate 15 climatological parameters and indices connected with viticulture. The next steps of the methodology are based on Geographic Information System methods. The topographical factors such as a slope gradient and slope exposure were created using Digital Elevation Models. The spatial distribution of climatological elements was interpolated by ordinary kriging. The values of each factor and indices were also ranked and classified. The viticultural potential was determined by integrating two suitability maps, i.e., the topographical and climatic ones, and by calculating the average for each pixel. Data analysis shows significant changes in heat accumulation indices that are driven by increases in maximum temperature, mostly increasing number of days with Tmax > 30˚C. The climatic conditions of this mesoregion are sufficient for vitis vinifera viticulture. The values of indicators and insolation are similar to those in the known wine regions located on similar geographical latitudes in Europe. The smallest threat to viticulture in study area is the occurrence of hail and the highest occurrence of frost in the winter. This research provides the basis for evaluating general suitability and climatologic potential for viticulture in Poland. To characterize the climatic potential for viticulture, it is necessary to assess the suitability of all climatological and topographical factors that can influence viticulture. The methodology used in this case study shows places where there is a possibility to create vineyards. It may also be helpful for wine-makers to select grape varieties.Keywords: climatologic potential, climatic classification, Poland, viticulture
Procedia PDF Downloads 10613556 Characterization of Self-Assembly Behavior of 1-Dodecylamine Molecules on Au (111) Surface
Authors: Wan-Tzu Yen, Yu-Chen Luo, I-Ping Liu, Po-Hsuan Yeh, Sheng-Hsun Fu, Yuh-Lang Lee
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Self-assembled characteristics and adsorption performance of 1-dodecylamine molecules on gold (Au) (111) surfaces were characterized via cyclic voltammetry (CV), surface-enhanced infrared absorption spectroscopy (SEIRAS) and scanning tunneling microscopy (STM). The present study focused on the formation of 1-dodecylamine (DDA) on a gold surface with respect to the ex-situ arrangement of an adlayer on the Au(111) surface, and phase transition at potential dynamics carried out by EC-STM. This study reveals that alkyl amine molecules were formed an adsorption pattern with highly regular “lie down shape” on Au(111) surface, even in an extreme acid system (pH = 1). Acidic electrolyte (HClO₄) could protonate the surface of alkyl amine of a monolayer of the gold surface when potential shifts to negative. The quite stability of 1-dodecylamine on the gold surface maintained the monolayer across the potential window (0.1-0.8V). This transform model was confirmed by EC-STM. In addition, amine-modified Au(111) electrode adlayer used to examine how to affect an electron transfer across an interface using [Fe(CN)₆]³⁻/[Fe(CN)₆]⁴⁻ redox pair containing 0.1 M HClO₄ solution.Keywords: cyclic voltammetry, dodecylamine, gold (Au)(111), scanning tunneling microscopy, self-assembled monolayer, surface-enhanced infrared absorption spectroscopy
Procedia PDF Downloads 19813555 Magneto-Solutal Convection in Newtonian Fluid Layer with Modulated Gravity
Authors: Om Prakash Keshri, Anand Kumar, Vinod K. Gupta
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In the present study, the effect of gravity modulation on the onset of convection in viscous fluid layer under the influence of induced magnetic field, salted from above on the boundaries, has been investigated. Linear and nonlinear stability analysis has been performed. A linear stability analysis is performed to show that the gravity modulation can significantly affect the stability limits of the system. A method based on small amplitude of the modulation is used to compute the critical value of Rayleigh number and wave number. The effect of Smith number, salute Rayleigh number and magnetic Prandtl number on the stability of the system is investigated.Keywords: viscous fluid, induced magnetic field, gravity modulation, salute convection
Procedia PDF Downloads 19013554 Antibacterial Property of ZnO Nanoparticles: Effect of Intrinsic Defects
Authors: Suresh Kumar Verma, Jugal Kishore Das, Ealisha Jha, Mrutyunjay Suar, SKS Parashar
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In recent years nanoforms of inorganic metallic oxides has attracted a lot of interest due to their small size and significantly improved physical, chemical and biological properties compared to their molecular precursor. Some of the inorganic materials such as TiO2, ZnO, MgO, CaO, Al2O3 have been extensively used in biological applications. Zinc Oxide is a Wurtzite-type semiconductor and piezo-electric material exhibiting excellent electrical, optical and chemical properties with a band energy gap of 3.1-3.4 eV. Nanoforms of Zinc Oxide (ZnO) are increasingly recognised for their utility in biological application. The significant physical parameters such as surface area, particle size, surface charge and Zeta potential of Zinc Oxide (ZnO) nanoparticles makes it suitable for the uptake, persistance, biological, and chemical activities inside the living cells. The present study shows the effect of intrinsic defects of ZnO nanocrystals synthesized by high energy ball milling (HEBM) technique in their antibacterial activities. Bulk Zinc oxide purchased from market were ball milled for 7 h, 10 h, and 15 h respectively to produce nanosized Zinc Oxide. The structural and optical modification of such synthesized particles were determined by X-ray diffraction (XRD), Scanning Electron Microscopy and Electron Paramagnetic Resonance (EPR). The antibacterial property of synthesized Zinc Oxide nanoparticles was tested using well diffusion, minimum inhibitory Concentration, minimum bacteriocidal concentration, reactive oxygen species (ROS) estimation and membrane potential determination methods. In this study we observed that antibacterial activity of ZnO nanoparticles is because of the intrinsic defects that exist as a function of difference in size and milling time.Keywords: high energy ball milling, ZnO nanoparticles, EPR, Antibacterial properties
Procedia PDF Downloads 42813553 Enabling Non-invasive Diagnosis of Thyroid Nodules with High Specificity and Sensitivity
Authors: Sai Maniveer Adapa, Sai Guptha Perla, Adithya Reddy P.
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Thyroid nodules can often be diagnosed with ultrasound imaging, although differentiating between benign and malignant nodules can be challenging for medical professionals. This work suggests a novel approach to increase the precision of thyroid nodule identification by combining machine learning and deep learning. The new approach first extracts information from the ultrasound pictures using a deep learning method known as a convolutional autoencoder. A support vector machine, a type of machine learning model, is then trained using these features. With an accuracy of 92.52%, the support vector machine can differentiate between benign and malignant nodules. This innovative technique may decrease the need for pointless biopsies and increase the accuracy of thyroid nodule detection.Keywords: thyroid tumor diagnosis, ultrasound images, deep learning, machine learning, convolutional auto-encoder, support vector machine
Procedia PDF Downloads 5813552 Energy States of Some Diatomic Molecules: Exact Quantization Rule Approach
Authors: Babatunde J. Falaye
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In this study, we obtain the approximate analytical solutions of the radial Schrödinger equation for the Deng-Fan diatomic molecular potential by using exact quantization rule approach. The wave functions have been expressed by hypergeometric functions via the functional analysis approach. An extension to rotational-vibrational energy eigenvalues of some diatomic molecules are also presented. It is shown that the calculated energy levels are in good agreement with the ones obtained previously E_nl-D (shifted Deng-Fan).Keywords: Schrödinger equation, exact quantization rule, functional analysis, Deng-Fan potential
Procedia PDF Downloads 49913551 The Role of NAD+ and Nicotinamide (Vitamin B3) in Glaucoma: A Literature Review
Authors: James Pietris
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Glaucoma is a collection of irreversible optic neuropathies which, if left untreated, lead to severe visual field loss. These diseases are a leading cause of blindness across the globe and are estimated to affect approximately 80 million people, particularly women and people of Asian descent.1This represents a major burden on healthcare systems worldwide. Recently, there has been increasing interest in the potential of nicotinamide (vitamin B3) as a novel option in the management of glaucoma. This review aims to analyse the currently available literature to determine whether there is evidence of an association between nicotinamide adenine dinucleotide (NAD+) and glaucomatous optic neuropathy and whether nicotinamide has the potential to prevent or reverse these effects. The literature showed a strong connection between reduced NAD+ levels and retinal ganglion cell dysfunction through multiple different studies. There is also evidence of the positive effect of nicotinamide supplementation on retinal ganglion cell function in models of mouse glaucoma and in a study involving humans. Based on the literature findings, a recommendation has been made that more research into the efficacy, appropriate dosing, and potential side effects of nicotinamide supplementation is needed before it can be definitively determined whether it is appropriate for widespread prophylactic and therapeutic use against glaucoma in humans.Keywords: glaucoma, nicotinamide, vitamin B3, optic neuropathy
Procedia PDF Downloads 10613550 Modified Fe₃O₄ Nanoparticles for Electrochemical Sensing of Heavy Metal Ions Pb²⁺, Hg²⁺, and Cd²⁺ in Water
Authors: Megha, Diksha, Seema Rani, Balwinder Kaur, Harminder Kaur
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Fe₃O₄@SiO₂@SB functionalized magnetic nanoparticles were synthesized and used to detect heavy metal ions such as Pb²⁺, Hg²⁺, and Cd²⁺ in water. The formation of Fe₃O₄@SiO₂@SB nanocatalyst was confirmed by XRD, SEM, TEM, and IR. The simultaneous determination of analyte cations was carried out using square wave anodic stripping voltammetry (SWASV). Investigation and optimisation were done to study how experimental variables affected the performance of the modified magnetic electrode. Pb²⁺, Hg²⁺, and Cd²⁺ were successfully detected using the designed sensor in the presence of various possibly interfering ions. The recovery rate was found to be 97.5% for Pb²⁺, 96.2% for Hg²⁺, 103.5% for Cd²⁺. The electrochemical sensor was also employed to determine the presence of heavy metal ions in drinking water samples, which are well below the World Health Organization (WHO) guidelines.Keywords: magnetic nanoparticles, heavy metal ions, electrochemical sensor, environmental water samples
Procedia PDF Downloads 7913549 Anthraquinone Labelled DNA for Direct Detection and Discrimination of Closely Related DNA Targets
Authors: Sarah A. Goodchild, Rachel Gao, Philip N. Bartlett
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A novel detection approach using immobilized DNA probes labeled with Anthraquinone (AQ) as an electrochemically active reporter moiety has been successfully developed as a new, simple, reliable method for the detection of DNA. This method represents a step forward in DNA detection as it can discriminate between multiple nucleotide polymorphisms within target DNA strands without the need for any additional reagents, reporters or processes such as melting of DNA strands. The detection approach utilizes single-stranded DNA probes immobilized on gold surfaces labeled at the distal terminus with AQ. The effective immobilization has been monitored using techniques such as AC impedance and Raman spectroscopy. Simple voltammetry techniques (Differential Pulse Voltammetry, Cyclic Voltammetry) are then used to monitor the reduction potential of the AQ before and after the addition of complementary strand of target DNA. A reliable relationship between the shift in reduction potential and the number of base pair mismatch has been established and can be used to discriminate between DNA from highly related pathogenic organisms of clinical importance. This indicates that this approach may have great potential to be exploited within biosensor kits for detection and diagnosis of pathogenic organisms in Point of Care devices.Keywords: Anthraquinone, discrimination, DNA detection, electrochemical biosensor
Procedia PDF Downloads 39313548 Practical Model of Regenerative Braking Using DC Machine and Boost Converter
Authors: Shah Krupa Rajendra, Amit Kumar
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Increasing use of traditional vehicles driven by internal combustion engine is responsible for the environmental pollution. Further, it leads to depletion of limited energy resources. Therefore, it is required to explore alternative energy sources for the transportation. The promising solution is to use electric vehicle. However, it suffers from limited driving range. Regenerative braking increases the range of the electric vehicle to a certain extent. In this paper, a novel methodology utilizing regenerative braking is described. The model comprising of DC machine, feedback based boost converter and micro-controller is proposed. The suggested method is very simple and reliable. The proposed model successfully shows the energy being saved into during regenerative braking process.Keywords: boost converter, DC machine, electric vehicle, micro-controller, regenerative braking
Procedia PDF Downloads 27213547 Comparison of the Boundary Element Method and the Method of Fundamental Solutions for Analysis of Potential and Elasticity
Authors: S. Zenhari, M. R. Hematiyan, A. Khosravifard, M. R. Feizi
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The boundary element method (BEM) and the method of fundamental solutions (MFS) are well-known fundamental solution-based methods for solving a variety of problems. Both methods are boundary-type techniques and can provide accurate results. In comparison to the finite element method (FEM), which is a domain-type method, the BEM and the MFS need less manual effort to solve a problem. The aim of this study is to compare the accuracy and reliability of the BEM and the MFS. This comparison is made for 2D potential and elasticity problems with different boundary and loading conditions. In the comparisons, both convex and concave domains are considered. Both linear and quadratic elements are employed for boundary element analysis of the examples. The discretization of the problem domain in the BEM, i.e., converting the boundary of the problem into boundary elements, is relatively simple; however, in the MFS, obtaining appropriate locations of collocation and source points needs more attention to obtain reliable solutions. The results obtained from the presented examples show that both methods lead to accurate solutions for convex domains, whereas the BEM is more suitable than the MFS for concave domains.Keywords: boundary element method, method of fundamental solutions, elasticity, potential problem, convex domain, concave domain
Procedia PDF Downloads 9013546 A Radiomics Approach to Predict the Evolution of Prostate Imaging Reporting and Data System Score 3/5 Prostate Areas in Multiparametric Magnetic Resonance
Authors: Natascha C. D'Amico, Enzo Grossi, Giovanni Valbusa, Ala Malasevschi, Gianpiero Cardone, Sergio Papa
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Purpose: To characterize, through a radiomic approach, the nature of areas classified PI-RADS (Prostate Imaging Reporting and Data System) 3/5, recognized in multiparametric prostate magnetic resonance with T2-weighted (T2w), diffusion and perfusion sequences with paramagnetic contrast. Methods and Materials: 24 cases undergoing multiparametric prostate MR and biopsy were admitted to this pilot study. Clinical outcome of the PI-RADS 3/5 was found through biopsy, finding 8 malignant tumours. The analysed images were acquired with a Philips achieva 1.5T machine with a CE- T2-weighted sequence in the axial plane. Semi-automatic tumour segmentation was carried out on MR images using 3DSlicer image analysis software. 45 shape-based, intensity-based and texture-based features were extracted and represented the input for preprocessing. An evolutionary algorithm (a TWIST system based on KNN algorithm) was used to subdivide the dataset into training and testing set and select features yielding the maximal amount of information. After this pre-processing 20 input variables were selected and different machine learning systems were used to develop a predictive model based on a training testing crossover procedure. Results: The best machine learning system (three-layers feed-forward neural network) obtained a global accuracy of 90% ( 80 % sensitivity and 100% specificity ) with a ROC of 0.82. Conclusion: Machine learning systems coupled with radiomics show a promising potential in distinguishing benign from malign tumours in PI-RADS 3/5 areas.Keywords: machine learning, MR prostate, PI-Rads 3, radiomics
Procedia PDF Downloads 18813545 Unlocking Green Hydrogen Potential: A Machine Learning-Based Assessment
Authors: Said Alshukri, Mazhar Hussain Malik
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Green hydrogen is hydrogen produced using renewable energy sources. In the last few years, Oman aimed to reduce its dependency on fossil fuels. Recently, the hydrogen economy has become a global trend, and many countries have started to investigate the feasibility of implementing this sector. Oman created an alliance to establish the policy and rules for this sector. With motivation coming from both global and local interest in green hydrogen, this paper investigates the potential of producing hydrogen from wind and solar energies in three different locations in Oman, namely Duqm, Salalah, and Sohar. By using machine learning-based software “WEKA” and local metrological data, the project was designed to figure out which location has the highest wind and solar energy potential. First, various supervised models were tested to obtain their prediction accuracy, and it was found that the Random Forest (RF) model has the best prediction performance. The RF model was applied to 2021 metrological data for each location, and the results indicated that Duqm has the highest wind and solar energy potential. The system of one wind turbine in Duqm can produce 8335 MWh/year, which could be utilized in the water electrolysis process to produce 88847 kg of hydrogen mass, while a solar system consisting of 2820 solar cells is estimated to produce 1666.223 MWh/ year which is capable of producing 177591 kg of hydrogen mass.Keywords: green hydrogen, machine learning, wind and solar energies, WEKA, supervised models, random forest
Procedia PDF Downloads 7913544 Performance Analysis of Vapour Compression Refrigeration System with Alternate Refrigerants
Authors: K. Parthiban, P. Pradeep, I. Pon Surya Prakash, S. Vinoth, A. Murugan
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The main aim of this project is to analyze the performance of vapor compression refrigeration system with alternate refrigerants. Currently we are using R134a as refrigerant. It is used in both household and industrial appliances as refrigerant. It has an advantage that the ozone depletion potential is zero i.e. R134a does not affects ozone layer. But its Global warming potential is considerably high. Also the compressor failure occurs frequently. Hence this project deals with how the performance of R134a varies with blended refrigerants such as R416a and R407c. This analysis is based on how much the Co-efficient of Performance (COP) varies with different refrigerants.Keywords: compressor, condenser, expansion valve, evaporator
Procedia PDF Downloads 322