Search results for: S. R. Satish Kumar
1683 Challenges in Multi-Cloud Storage Systems for Mobile Devices
Authors: Rajeev Kumar Bedi, Jaswinder Singh, Sunil Kumar Gupta
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The demand for cloud storage is increasing because users want continuous access their data. Cloud Storage revolutionized the way how users access their data. A lot of cloud storage service providers are available as DropBox, G Drive, and providing limited free storage and for extra storage; users have to pay money, which will act as a burden on users. To avoid the issue of limited free storage, the concept of Multi Cloud Storage introduced. In this paper, we will discuss the limitations of existing Multi Cloud Storage systems for mobile devices.Keywords: cloud storage, data privacy, data security, multi cloud storage, mobile devices
Procedia PDF Downloads 6991682 Rashba Spin Orbit Interaction Effect on Multiphoton Optical Transitions in a Quantum Dot for Bioimaging
Authors: Pradip Kumar Jha, Manoj Kumar
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We demonstrate in this work the effect of Rashba spin orbit interaction on multiphoton optical transitions of a quantum dot in the presence of THz laser field and external static magnetic field. This combination is solved by accurate non-perturbative Floquet theory. Investigations are made for the optical response of intraband transition between the various states of the conduction band with spin flipping. Enhancement and power broadening observed for excited states probabilities with increase of external fields are directly linked to the emission spectra of QD and will be useful for making future bioimaging devices.Keywords: bioimaging, multiphoton processes, spin orbit interaction, quantum dot
Procedia PDF Downloads 4801681 Design of Lead-Lag Based Internal Model Controller for Binary Distillation Column
Authors: Rakesh Kumar Mishra, Tarun Kumar Dan
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Lead-Lag based Internal Model Control method is proposed based on Internal Model Control (IMC) strategy. In this paper, we have designed the Lead-Lag based Internal Model Control for binary distillation column for SISO process (considering only bottom product). The transfer function has been taken from Wood and Berry model. We have find the composition control and disturbance rejection using Lead-Lag based IMC and comparing with the response of simple Internal Model Controller.Keywords: SISO, lead-lag, internal model control, wood and berry, distillation column
Procedia PDF Downloads 6461680 Potentially Inappropriate Prescribing in Elderly Population
Authors: Ajit Kumar Sah, Rajesh Kumar Jha, Phoolgen Sah, Dev Kumar Shah
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Older individuals often suffer from multiple systemic diseases and are particularly more vulnerable to potentially inappropriate medicine prescribing. Inappropriate medication can cause serious medical problem for the elderly. The purpose of this study was to determine the prevalence of potentially inappropriate medicine (PIM) prescribing in older Nepalese patients in a medicine outpatient department. Beers’ criteria are the most widely used tools to assess PIM to elderly patients. Prospective observational analysis of drugs prescribed in medicine out-patient department (OPD) of a hospital of Bharatpur, Chitwan, Nepal during November 2011 to October 2012 to 869 older adults aged 65 years and above. The use of potentially inappropriate medications (PIM) in elderly patients was analyzed using Beers Criteria updated to 2013. In the 869 patients included the average number of drugs prescribed per prescription was 5.56. The most commonly used drugs were atenolol (24.3%), amlodipine (23.16%), paracetamol (17.6%), salbutamol (15.72%) and vitamin B complex (13.26%). The total number of medications prescribed was 4833. At least one instance of PIM was experienced by approximately 26.3% of patients when evaluated using the Beers criteria. Potentially inappropriate medications are highly prevalent among older patients attending medical OPD and are associated with a number of medications prescribed. Further research is warranted to study the impact of PIMs towards health-related outcomes in these elderly.Keywords: Beers criteria, elderly, polypharmacy, potentially inappropriate medicines
Procedia PDF Downloads 5661679 Modulational Instability of Ion-Acoustic Wave in Electron-Positron-Ion Plasmas with Two-Electron Temperature Distributions
Authors: Jitendra Kumar Chawla, Mukesh Kumar Mishra
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The nonlinear amplitude modulation of ion-acoustic wave is studied in the presence of two-electron temperature distribution in unmagnetized electron-positron-ion plasmas. The Krylov-Bogoliubov-Mitropolosky (KBM) perturbation method is used to derive the nonlinear Schrödinger equation. The dispersive and nonlinear coefficients are obtained which depend on the temperature and concentration of the hot and cold electron species as well as the positron density and temperature. The modulationally unstable regions are studied numerically for a wide range of wave number. The effects of the temperature and concentration of the hot and cold electron on the modulational stability are investigated in detail.Keywords: modulational instability, ion acoustic wave, KBM method
Procedia PDF Downloads 6651678 Temperature Dependent Tribological Properties of Graphite
Authors: Pankaj Kumar Das, Niranjan Kumar, Prasun Chakraborti
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Temperature dependent tribologiocal properties of nuclear grade turbostatic graphite were studied using 100Cr6 steel counterbody. High value of friction coefficient (0.25) and high wear loss was observed at room temperature and this value decreased to 0.1 at 150oC. Consequently, wear loss is also decreased. Such behavior is explained by oxidation/vaporization of graphite and water molecules. At room temperature, the adsorbed water in graphite does not decompose and effect of passivation mechanism does not work. However, at 150oC, the water decomposed into OH, atomic hydrogen and oxygen which efficiently passivates the carbon dangling bonds. This effect is known to decrease the energy of the contact and protect against abrasive wear.Keywords: high temperature tribology, oxidation, turbostratic graphite, wear
Procedia PDF Downloads 5141677 Modeling and Simulation of Underwater Flexible Manipulator as Raleigh Beam Using Bond Graph
Authors: Sumit Kumar, Sunil Kumar, Chandan Deep Singh
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This paper presents modeling and simulation of flexible robot in an underwater environment. The underwater environment completely contrasts with ground or space environment. The robot in an underwater situation is subjected to various dynamic forces like buoyancy forces, hydrostatic and hydrodynamic forces. The underwater robot is modeled as Rayleigh beam. The developed model further allows estimating the deflection of tip in two directions. The complete dynamics of the underwater robot is analyzed, which is the main focus of this investigation. The control of robot trajectory is not discussed in this paper. Simulation is performed using Symbol Shakti software.Keywords: bond graph modeling, dynamics. modeling, rayleigh beam, underwater robot
Procedia PDF Downloads 5861676 Experimental Challenges and Solutions in Design and Operation of the Test Rig for Water Lubricated Journal Bearing
Authors: Ravindra Mallya, B. Satish Shenoy, B. Raghuvir Pai
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The study deals with the challenges in developing a test rig to test the performance of water lubricated journal bearing. The test rig is designed to simulate the working conditions of the bearing in order to understand their performance before they are put in operation. The bearing that is studied is the commercially available water lubricated bearing which has a rubber liner bonded with a rigid metal shell. The lubricant enters the bearing axially through a pressurized inlet tank and exits to an outlet tank which is at sufficiently low pressure. The load on the bearing is applied through the dead weight system which acts both in upward and downward direction so that net load acts on the bearing. The issues in feeding the lubricant into the bearing from the inlet side and preventing the leakage of the lubricant is discussed. The application of the load on the test bearing while maintaining the bearing afloat is also discussed.Keywords: axial groove, hydrodynamic pressure, journal bearing, test rig, water lubrication
Procedia PDF Downloads 5021675 To Individualisation of Subject, Donar, by Determination of Serological Markers from Obtain Biological Fluid at Crime Scene
Authors: Arun Kumar, Ravindra Pal Verma, Harsh Sharma, Shani Kumar
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For the present study samples was collected from 20 donors with unknown blood group and secretor status had been determined from saliva by using biological fluid. ABO typing on the concentrated samples was successfully performed after 1 month of storage. Urine stained clothing samples are often submitted to forensic science laboratories for ABH blood group antigen determination. The serogenetic markers of semen stains submitted can be used to determine the origin of any of these samples. ABH blood group substances have previously been identified from urine. ABH blood group substance is low in urine in comparison with other body fluids.Keywords: ABH blood group, crime scene, serological markers, body fluids and urine
Procedia PDF Downloads 5871674 Biosorption of Phenol onto Water Hyacinth Activated Carbon: Kinetics and Isotherm Study
Authors: Manoj Kumar Mahapatra, Arvind Kumar
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Batch adsorption experiments were carried out for the removal of phenol from its aqueous solution using water hyancith activated carbon (WHAC) as an adsorbent. The sorption kinetics were analysed using pseudo-first order kinetics and pseudo-second order model, and it was observed that the sorption data tend to fit very well in pseudo-second order model for the entire sorption time. The experimental data were analyzed by the Langmuir and Freundlich isotherm models. Equilibrium data fitted well to the Freundlich model with a maximum biosorption capacity of 31.45 mg/g estimated using Langmuir model. The adsorption intensity 3.7975 represents a favorable adsorption condition.Keywords: adsorption, isotherm, kinetics, phenol
Procedia PDF Downloads 4441673 Field Experience with Sweep Frequency Response Analysis for Power Transformer Diagnosis
Authors: Ambuj Kumar, Sunil Kumar Singh, Shrikant Singh, Zakir Husain, R. K. Jarial
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Sweep frequency response analysis has been turning out a powerful tool for investigation of mechanical as well as electrical integration of transformers. In this paper various aspect of practical application of SFRA has been studied. Open circuit and short circuit measurement were done on different phases of high voltage and low voltage winding. A case study was presented for the transformer of rating 31.5 MVA for various frequency ranges. A clear picture was presented for sub- frequency ranges for HV as well as LV winding. The main motive of work is to investigate high voltage short circuit response. The theoretical concept about SFRA responses is validated with expert system software results.Keywords: transformer winding, SFRA, OCT & SCT, frequency deviation
Procedia PDF Downloads 9571672 Optimization of Bioremediation Process to Remove Hexavalent Chromium from Tannery Effluent
Authors: Satish Babu Rajulapati
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The removal of toxic and heavy metal contaminants from wastewater streams and industrial effluents is one of the most important environmental issues being faced world over. In the present study three bacterial cultures tolerating high concentrations of chromium were isolated from the soil and wastewater sample collected from the tanneries located in Warangal, Telangana state. The bacterial species were identified as Bacillus sp., Staphylococcus sp. and pseudomonas sp. Preliminary studies were carried out with the three bacterial species at various operating parameters such as pH and temperature. The results indicate that pseudomonas sp. is the efficient one in the uptake of Cr(VI). Further, detailed investigation of Pseudomonas sp. have been carried out to determine the efficiency of removal of Cr(VI). The various parameters influencing the biosorption of Cr(VI) such as pH, temperature, initial chromium concentration, innoculum size and incubation time have been studied. Response Surface Methodology (RSM) was applied to optimize the removal of Cr(VI). Maximum Cr(VI) removal was found to be 85.72% Cr(VI) atpH 7, temperature 35 °C, initial concentration 67mg/l, inoculums size 9 %(v/v) and time 60 hrs.Keywords: Staphylococcus sp, chromium, RSM, optimization, Cr(IV)
Procedia PDF Downloads 3241671 A Double Epilayer PSGT Trench Power MOSFETs for Low to Medium Voltage Power Applications
Authors: Alok Kumar Kamal, Vinod Kumar
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The trench gate MOSFET has shown itself as the most appropriate power device for low to medium voltage power applications due to its lowest possible ON resistance among all power semiconductor devices. In this research work a double-epilayer PSGT structure using a thin layer of N+ polysilicon as gate material. The total ON-state resistance (RON) of UMOSFET can be reduced by optimizing the epilayer thickness. The optimized structure of Double-Epilayer exhibits a 25.8% reduction in the ON-state resistance at Vgs=5V and improving the switching characteristics by reducing the Reverse transfer capacitance (Cgd) by 7.4%.Keywords: Miller-capacitance, double-Epilayer;switching characteristics, power trench MOSFET (U-MOSFET), on-state resistance, blocking voltage
Procedia PDF Downloads 721670 Speed Characteristics of Mixed Traffic Flow on Urban Arterials
Authors: Ashish Dhamaniya, Satish Chandra
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Speed and traffic volume data are collected on different sections of four lane and six lane roads in three metropolitan cities in India. Speed data are analyzed to fit the statistical distribution to individual vehicle speed data and all vehicles speed data. It is noted that speed data of individual vehicle generally follows a normal distribution but speed data of all vehicle combined at a section of urban road may or may not follow the normal distribution depending upon the composition of traffic stream. A new term Speed Spread Ratio (SSR) is introduced in this paper which is the ratio of difference in 85th and 50th percentile speed to the difference in 50th and 15th percentile speed. If SSR is unity then speed data are truly normally distributed. It is noted that on six lane urban roads, speed data follow a normal distribution only when SSR is in the range of 0.86 – 1.11. The range of SSR is validated on four lane roads also.Keywords: normal distribution, percentile speed, speed spread ratio, traffic volume
Procedia PDF Downloads 4221669 Extraction of Strontium Ions through Ligand Assisted Ionic Liquids
Authors: Pradeep Kumar, Abhishek Kumar Chandra, Ashok Khanna
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Extraction of Strontium by crown ether (DCH18C6) hasbeen investigated in [BMIM][TF2N] Ionic Liquid (IL) giving higher extraction ~98% and distribution ratio as compared to other organic solvents (Dodecane, Hexane, & Isodecyl alcohol + Dodecane). Distribution ratio of Sr in IL at 0.15M DCH18C6 indicates an enhancement of 20000, 2000, 500 times over Dodecane, Hexane and 5% Isodecyl Alcohol + 95 % Dodecane at 0.01M aqueous acidity respectively. In presence of IL, Sr extraction decreases with increase in HNO3 concentration in aqueous phase whereas opposite trend was observed with organic solvents.Extraction of Sr initially increases with increase in DCH18C6 concentration in IL, finally reaching an asymptotic constant.Keywords: distribution ratio, ionic liquid, ligand, organic solvent, stripping
Procedia PDF Downloads 4431668 Surface Roughness Effects in Pure Sliding EHL Line Contacts with Carreau-Type Shear-Thinning Lubricants
Authors: Punit Kumar, Niraj Kumar
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The influence of transverse surface roughness on EHL characteristics has been investigated numerically using an extensive set of full EHL line contact simulations for shear-thinning lubricants under pure sliding condition. The shear-thinning behavior of lubricant is modeled using Carreau viscosity equation along with Doolittle-Tait equation for lubricant compressibility. The surface roughness is assumed to be sinusoidal and it is present on the stationary surface. It is found that surface roughness causes sharp pressure peaks along with reduction in central and minimum film thickness. With increasing amplitude of surface roughness, the minimum film thickness decreases much more rapidly as compared to the central film thickness.Keywords: EHL, Carreau, shear-thinning, surface roughness, amplitude, wavelength
Procedia PDF Downloads 7311667 A Review of Fractal Dimension Computing Methods Applied to Wear Particles
Authors: Manish Kumar Thakur, Subrata Kumar Ghosh
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Various types of particles found in lubricant may be characterized by their fractal dimension. Some of the available methods are: yard-stick method or structured walk method, box-counting method. This paper presents a review of the developments and progress in fractal dimension computing methods as applied to characteristics the surface of wear particles. An overview of these methods, their implementation, their advantages and their limits is also present here. It has been accepted that wear particles contain major information about wear and friction of materials. Morphological analysis of wear particles from a lubricant is a very effective way for machine condition monitoring. Fractal dimension methods are used to characterize the morphology of the found particles. It is very useful in the analysis of complexity of irregular substance. The aim of this review is to bring together the fractal methods applicable for wear particles.Keywords: fractal dimension, morphological analysis, wear, wear particles
Procedia PDF Downloads 4901666 Design and Optimization of a Mini High Altitude Long Endurance (HALE) Multi-Role Unmanned Aerial Vehicle
Authors: Vishaal Subramanian, Annuatha Vinod Kumar, Santosh Kumar Budankayala, M. Senthil Kumar
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This paper discusses the aerodynamic and structural design, simulation and optimization of a mini-High Altitude Long Endurance (HALE) UAV. The applications of this mini HALE UAV vary from aerial topological surveys, quick first aid supply, emergency medical blood transport, search and relief activates to border patrol, surveillance and estimation of forest fire progression. Although classified as a mini UAV according to UVS International, our design is an amalgamation of the features of ‘mini’ and ‘HALE’ categories, combining the light weight of the ‘mini’ and the high altitude ceiling and endurance of the HALE. Designed with the idea of implementation in India, it is in strict compliance with the UAS rules proposed by the office of the Director General of Civil Aviation. The plane can be completely automated or have partial override control and is equipped with an Infra-Red camera and a multi coloured camera with on-board storage or live telemetry, GPS system with Geo Fencing and fail safe measures. An additional of 1.5 kg payload can be attached to three major hard points on the aircraft and can comprise of delicate equipment or releasable payloads. The paper details the design, optimization process and the simulations performed using various software such as Design Foil, XFLR5, Solidworks and Ansys.Keywords: aircraft, endurance, HALE, high altitude, long range, UAV, unmanned aerial vehicle
Procedia PDF Downloads 3961665 Hydro-Chemical Characterization of Glacial Melt Waters Draining from Shaune Garang Glacier, Himachal Himalaya
Authors: Ramesh Kumar, Rajesh Kumar, Shaktiman Singh, Atar Singh, Anshuman Bhardwaj, Ravindra Kumar Sinha, Anupma Kumari
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A detailed study of the ion chemistry of the Shaune Garnag glacier meltwater has been carried out to assess the role of active glacier in the chemical denudation rate. The chemical compositions of various ions in meltwater of the Shaune Garang glacier were analyzed during the melting period 2015 and 2016. Total 112 of melt water samples twice in a day were collected during ablation season of 2015 and 2016. To identify various factors controlling the dissolved ionic strength of Shaune Garang Glacier meltwater statistical analysis such as correlation matrix, Principle Component Analysis (PCA) and factor analysis were applied to deduce the result. Cation concentration for Ca²⁺ > Mg²⁺ > Na⁺ > K⁺ in the meltwater for both the years can be arranged in the order as Ca²⁺ > Mg²⁺ > Na⁺ > K⁺. Study showed that Ca²⁺ and HCO₃⁻ found to be dominant on the both melting period. Carbonate weathering identified as the dominant process controlling the dissolved ion chemistry of meltwater due to the high ratios of (Ca²⁺ + Mg²⁺) versus TZ+ and (Ca²⁺ + Mg²⁺) versus (Na⁺ + K⁺) in the study area. The cation denudation rate of the Shaune Garnag catchment is 3412.2 m⁻² a⁻¹, i.e. higher than the other glacierised catchment in the Himalaya, indicating intense chemical erosion in this catchment.Keywords: Shaune Garang glacier, Hydrochemistry, chemical composition, cation denudation rate, carbonate weathering
Procedia PDF Downloads 3761664 Tracing Economic Policies to Ancient Indian Economic Thought
Authors: Satish Y. Deodhar
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Science without history is like a man without memory. The colossal history of India stores many ideas on economic ethics and public policy, which have been forgotten in the course of time. This paper is an attempt to bring to the fore contributions from ancient Indian treatises. In this context, the paper briefly summarizes alternative economic ideas such as communism, capitalism, and the holistic approach of ancient Indian writings. Thereafter, the idea of a welfare brick for an individual consisting of three dimensions -Purusharthas, Ashramas, and Varnas is discussed. Given the contours of the welfare brick, the concept of the state, its economic policies, markets, prices, interest rates, and credit are covered next. This is followed by delving into the treatment of land, property rights, guilds, and labour relations. The penultimate section summarises the economic advice offered to the head of a household in the treatise Shukranitisara. Finally, in concluding comments, the relevance of ancient Indian writings for modern times is discussed -both for pedagogy and economic policies.Keywords: ancient Indian treatises, history of economic thought, science of political economy, Sanskrit
Procedia PDF Downloads 971663 Comparison of Different Methods of Evaluating Nozzle Junction Stresses under External Loads
Authors: Vinod Kumar, Arun Kumar, Surjit Angra
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This paper addresses the junction stress analysis of orthogonally intersecting thin walled cylindrical shell and thin walled cylindrical nozzle subjected to external loading on nozzle. Junction stresses have been calculated theoretically by welding research council (WRC) bulletins 107 and 297 for different nozzle loads. WRC bulletins 107 and 297 have been used by design engineers for calculating nozzle-vessel junction stresses since their publication. They give simple empirical relations and easy in application. Also 3D FEA in which material is elastic has been done in ANSYS software with 8 node solid element model and results of FEA have been compared with WRC results. Stress intensities obtained by WRC 297 are generally slightly higher than obtained by WRC 107. Membrane stresses obtained by FEA are much higher than WRC and membrane plus bending stresses obtained by FEA are lower than WRC.Keywords: FEA, junction stress, solid element, WRC 107, WRC 297
Procedia PDF Downloads 5791662 Performance and Emissions Analysis of Diesel Engine with Bio-Diesel of Waste Cooking Oils
Authors: Mukesh Kumar, Onkar Singh, Naveen Kumar, Amar Deep
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The waste cooking oil is taken as feedstock for biodiesel production. For this research, waste cooking oil is collected from many hotels and restaurants, and then biodiesel is prepared for experimentation purpose. The prepared biodiesel is mixed with mineral diesel in the proportion of 10%, 20%, and 30% to perform tests on a diesel engine. The experimental analysis is carried out at different load conditions to analyze the impact of the blending ratio on the performance and emission parameters. When the blending proportion of biodiesel is increased, then the highest pressure reduces due to the fall in the calorific value of the blended mixture. Experimental analysis shows a promising decrease in nitrogen oxides (NOx). A mixture of 20% biodiesel and mineral diesel is the best negotiation, mixing ratio, and beyond that, a remarkable reduction in the outcome of the performance has been observed.Keywords: alternative sources, diesel engine, emissions, performance
Procedia PDF Downloads 1791661 Dynamic Soil Structure Interaction in Buildings
Authors: Shreya Thusoo, Karan Modi, Ankit Kumar Jha, Rajesh Kumar
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Since the evolution of computational tools and simulation software, there has been considerable increase in research on Soil Structure Interaction (SSI) to decrease the computational time and increase accuracy in the results. To aid the designer with a proper understanding of the response of structure in different soil types, the presented paper compares the deformation, shear stress, acceleration and other parameters of multi-storey building for a specific input ground motion using Response-spectrum Analysis (RSA) method. The response of all the models of different heights have been compared in different soil types. Finite Element Simulation software, ANSYS, has been used for all the computational purposes. Overall, higher response is observed with SSI, while it increases with decreasing stiffness of soil.Keywords: soil-structure interaction, response spectrum, analysis, finite element method, multi-storey buildings
Procedia PDF Downloads 4801660 A Novel Method for Silence Removal in Sounds Produced by Percussive Instruments
Authors: B. Kishore Kumar, Rakesh Pogula, T. Kishore Kumar
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The steepness of an audio signal which is produced by the musical instruments, specifically percussive instruments is the perception of how high tone or low tone which can be considered as a frequency closely related to the fundamental frequency. This paper presents a novel method for silence removal and segmentation of music signals produced by the percussive instruments and the performance of proposed method is studied with the help of MATLAB simulations. This method is based on two simple features, namely the signal energy and the spectral centroid. As long as the feature sequences are extracted, a simple thresholding criterion is applied in order to remove the silence areas in the sound signal. The simulations were carried on various instruments like drum, flute and guitar and results of the proposed method were analyzed.Keywords: percussive instruments, spectral energy, spectral centroid, silence removal
Procedia PDF Downloads 4111659 Study the Sloshing Phenomenon in the Tank Filled Partially with Liquid Using Computational Fluid Dynamics (CFD) Simulation
Authors: Amit Kumar, Jaikumar V., Pradeep A. G., Shivakumar Bhavi
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Amit Kumar, Jaikumar V, Pradeep AG, Shivakumar Bhavi Reducing sloshing is one of the major challenges in industries where transporting of liquid is involved. The present study investigates the sloshing effect for different liquid levels of 50% of the tank capacity. CFD simulation for two different baffle configurations has been carried out using a time-based multiphase Volume of fluid (VOF) scheme. Baffles were introduced to examine the sloshing effect inside the tank. Results were compared against the baseline case to assess the effectiveness of baffles; maximum liquid height over the period of the simulation was considered as the parameter for measuring the sloshing effect inside the tank. It was found that the addition of baffles reduced the sloshing effect inside the tank as compared to the baseline model.Keywords: CFD, sloshing, VOF, multiphase
Procedia PDF Downloads 1921658 Effect of SCN5A Gene Mutation in Endocardial Cell
Authors: Helan Satish, M. Ramasubba Reddy
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The simulation of an endocardial cell for gene mutation in the cardiac sodium ion channel NaV1.5, encoded by SCN5A gene, is discussed. The characterization of Brugada Syndrome by loss of function effect on SCN5A mutation due to L812Q mutant present in the DII-S4 transmembrane region of the NaV1.5 channel protein and its effect in an endocardial cell is studied. Ten Tusscher model of human ventricular action potential is modified to incorporate the changes contributed by L812Q mutant in the endocardial cells. Results show that BrS-associated SCN5A mutation causes reduction in the inward sodium current by modifications in the channel gating dynamics such as delayed activation, enhanced inactivation, and slowed recovery from inactivation in the endocardial cell. A decrease in the inward sodium current was also observed, which affects depolarization phase (Phase 0) that leads to reduction in the spike amplitude of the cardiac action potential.Keywords: SCN5A gene mutation, sodium channel, Brugada syndrome, cardiac arrhythmia, action potential
Procedia PDF Downloads 1261657 A Multi-Release Software Reliability Growth Models Incorporating Imperfect Debugging and Change-Point under the Simulated Testing Environment and Software Release Time
Authors: Sujit Kumar Pradhan, Anil Kumar, Vijay Kumar
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The testing process of the software during the software development time is a crucial step as it makes the software more efficient and dependable. To estimate software’s reliability through the mean value function, many software reliability growth models (SRGMs) were developed under the assumption that operating and testing environments are the same. Practically, it is not true because when the software works in a natural field environment, the reliability of the software differs. This article discussed an SRGM comprising change-point and imperfect debugging in a simulated testing environment. Later on, we extended it in a multi-release direction. Initially, the software was released to the market with few features. According to the market’s demand, the software company upgraded the current version by adding new features as time passed. Therefore, we have proposed a generalized multi-release SRGM where change-point and imperfect debugging concepts have been addressed in a simulated testing environment. The failure-increasing rate concept has been adopted to determine the change point for each software release. Based on nine goodness-of-fit criteria, the proposed model is validated on two real datasets. The results demonstrate that the proposed model fits the datasets better. We have also discussed the optimal release time of the software through a cost model by assuming that the testing and debugging costs are time-dependent.Keywords: software reliability growth models, non-homogeneous Poisson process, multi-release software, mean value function, change-point, environmental factors
Procedia PDF Downloads 741656 Beating Heart Coronary Artery Bypass Grafting on Intermittent Pump Support
Authors: Sushil Kumar Singh, Vivek Tewarson, Sarvesh Kumar, Shobhit Kumar
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Objective: ‘Beating Heart coronary artery bypass grafting on Intermittent Pump Support’ is a more reliable method of coronary revascularization that takes advantage of off and on-pump CABG while eliminating the disadvantage of both techniques. Methods: From January 2015 to December 2021, a new technique, “Intermittent On pump beating heart CABG” using a suction stabilizer was used by putting aortic and venous cannulas electively in all the patients. Patients were supported by a pump intermittently, as and when required (Group 1, n=254). Retrospective data were collected from our record of the patients who underwent off-pump CABG electively by the same surgeon and team (Group 2, n=254). Results: Significant advantage was noted in Group 1 patients in terms of the number of grafts (3.31 ± 1.16 vs. 2.30 ±0.66), grafting of lateral vessels (316 vs.202), mean operating time (1.37 ± 0.23 hrs vs. 2.22 ± 0.45 hrs) and postoperative blood loss (406.30 ± 257.90 ml vs. 567.41 ± 265.20 ml).CPB support time was less than 15 minutes in the majority of patients (n=179, 70.37 %), with a mean of 16.81 minutes. It was required, particularly during the grafting of lateral vessels. A rise in enzymes level (CRP, CKMB, Trop I, and NTPro BNP) was noted in Group 1 patients. But, these did not affect the postoperative course in patients. There was no mortality in Group 1 patients, while four patients in Group 2 died. Coclusions: Intermittent on-pump CABG technique is a promising method of surgical revascularization for all patients requiring CABG. It has shown its superiority in terms of safety, the number of grafts, operating time, and better perioperative course.Keywords: cardiopulmonary bypass, CABG, beating heart CABG, on-pump CABG
Procedia PDF Downloads 1201655 Drum Scrubber Performance Assessment and Improvement to Achieve the Desired Product Quality
Authors: Prateek Singh, Arun Kumar Pandey, C. Raghu Kumar, M. R. Rath, A. S. Reddy
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Drum scrubber is widely used equipment in the washing of Iron ore. The purpose of the scrubber is to release the adhered fine clayey particles from the iron-bearing particles. Presently, the iron ore wash plants in the Eastern region of India consist of the scrubber, double deck screen followed by screw classifier as the main unit operations. Hence, scrubber performance efficiency has a huge impact on the downstream product quality. This paper illustrates the effect of scrubber feed % solids on scrubber performance and alumina distribution on downstream equipment. Further, it was established that scrubber performance efficiency could be defined as the ratio of the adhered particles (-0.15mm) released from scrubber feed during scrubbing operation with respect to the maximum possible release of -0.15mm (%) particles.Keywords: scrubber, adhered particles, feed % solids, efficiency
Procedia PDF Downloads 1381654 Numerical Investigation of Pressure Drop and Erosion Wear by Computational Fluid Dynamics Simulation
Authors: Praveen Kumar, Nitin Kumar, Hemant Kumar
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The modernization of computer technology and commercial computational fluid dynamic (CFD) simulation has given better detailed results as compared to experimental investigation techniques. CFD techniques are widely used in different field due to its flexibility and performance. Evaluation of pipeline erosion is complex phenomenon to solve by numerical arithmetic technique, whereas CFD simulation is an easy tool to resolve that type of problem. Erosion wear behaviour due to solid–liquid mixture in the slurry pipeline has been investigated using commercial CFD code in FLUENT. Multi-phase Euler-Lagrange model was adopted to predict the solid particle erosion wear in 22.5° pipe bend for the flow of bottom ash-water suspension. The present study addresses erosion prediction in three dimensional 22.5° pipe bend for two-phase (solid and liquid) flow using finite volume method with standard k-ε turbulence, discrete phase model and evaluation of erosion wear rate with varying velocity 2-4 m/s. The result shows that velocity of solid-liquid mixture found to be highly dominating parameter as compared to solid concentration, density, and particle size. At low velocity, settling takes place in the pipe bend due to low inertia and gravitational effect on solid particulate which leads to high erosion at bottom side of pipeline.Keywords: computational fluid dynamics (CFD), erosion, slurry transportation, k-ε Model
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