Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 2

edema Related Abstracts

2 Clinical and Epidemiological Profile in Patients with Preeclampsia in a Private Institution in Medellin, Colombia 2015

Authors: Lina María Martínez Sánchez, María de los Ángeles Rodríguez Gázquez, Natalia Perilla Hernández, Isabel Cristina Ortiz Trujillo, Felipe Hernández Restrepo, Camilo Andrés Agudelo Vélez, Evert Armando Jiménez Cotes, Daniel Duque Restrepo, Dayana Andrea Quintero Moreno, Juan José Builes Gómez, Camilo Ruiz Mejía, Ana Lucia Arango Gómez

Abstract:

Preeclampsia is a clinical complication during pregnancy with high incidence in Colombia; therefore, it is important to evaluate the influence of external conditions and medical interventions, in order to promote measures that encourage improvements in the quality of life. Objective: Determine clinical and sociodemographic variables in women with preeclampsia. Methods: This cross-sectional study enrolled 50 patients with the diagnosis of preeclampsia, from a private institution in Medellin, during 2015. We used the software SPSS ver.20 for statistical analysis. For the qualitative variables, we calculated the mean and standard deviation, while, for ordinal and nominal levels of quantitative variables, ratios were estimated. Results: The average age was 26.8±5.9 years. The predominant characteristics were socioeconomic stratum 2 (48%), students (55%), mixed race (46%) and middle school as level of education (38%). As for clinical features, 72% of the cases were mild preeclampsia, and 22% were severe forms. The most common clinical manifestations were edema (46%), headache (62%), and proteinuria (55%). As for the Gyneco-obstetric history, 8% reported previous episodes of this disease and it was the first pregnancy for 60% of the patients. Conclusions: Preeclampsia is a frequent condition in young women; on the other hand, headache and edema were the most common reasons for consultation, therefore, doctors need to be aware of these symptoms in pregnant women.

Keywords: pregnancy, Hypertension, pregnancy complications, pre-eclampsia, abdominal, edema

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1 In vivo Evaluation of the Anti-Inflammatory, Analgesic Activities of Crataegus Sinaica Methanol Extract

Authors: Rehab F. Abdel-Rahman, A. H. El-Desoky, Gihan F. Asaad

Abstract:

Objective: The research was designed to study the anti-inflammatory and analgesic effect of Crataegus sinaica methanol extract Methods: The anti-inflammatory were measured by edema rate and inhibition rate using plethysmometer and by determinig PGE2, TNF-ɑ and MPO levels in paw exudate. Both central and peripheral analgesic effect were examined using Writhing test and hot plate test Key Findings: The methanolic extract showed a significant anti-inflammatory effect by decreasing paw edema induced by carrageenan; also results showed that anti-inflammatory effect increased by increasing the dose. All dose levels of the extract showed significant reduction in Prostaglandin E2, Tumor necrosis factor-ɑ, and Meyloperoxidase levels. Crataegus sinaica methanol extract showed both peripheral and central analgesic effect. Conclusion: The C. sinaica methanolic extract can be considered a promising anti-inflammatory and analgesic product.

Keywords: Pain, Analgesia, prostaglandins, edema, Crataegus sinaica, hot plate

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