%0 Journal Article
	%A Amirali Ebrahimi and  T. A. G. Langrish
	%D 2014
	%J International Journal of Chemical and Molecular Engineering
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 94, 2014
	%T Effect of Humidity on in-Process Crystallization of Lactose during Spray Drying
	%U https://publications.waset.org/pdf/9999522
	%V 94
	%X The effect of various humidities on process yields and
degrees of crystallinity for spray-dried powders from spray drying of
lactose with humid air in a straight-through system have been
studied. It has been suggested by Williams–Landel–Ferry kinetics
(WLF) that a higher particle temperature and lower glass-transition
temperature would increase the crystallization rate of the particles
during the spray-drying process. Freshly humidified air produced by
a Buchi-B290 spray dryer as a humidifier attached to the main spray
dryer decreased the particle glass-transition temperature (Tg), while
allowing the particle temperature (Tp) to reach higher values by using
an insulated drying chamber. Differential scanning calorimetry
(DSC) and moisture sorption analysis were used to measure the
degree of crystallinity for the spray-dried lactose powders. The
results showed that higher Tp-Tg, as a result of applying humid air,
improved the process yield from 21 ± 4 to 26 ± 2% and crystallinity
of the particles by decreasing the latent heat of crystallization from
43 ± 1 to 30 ± 11 J/g and the sorption peak height from 7.3 ± 0.7% to
6 ± 0.7%.

	%P 1105 - 1108