%0 Journal Article %A Vladimir V. Iakovlev and Erin T. Carey and John Steege %D 2014 %J International Journal of Medical and Health Sciences %B World Academy of Science, Engineering and Technology %I Open Science Index 93, 2014 %T Pathology of Explanted Transvaginal Meshes %U https://publications.waset.org/pdf/9999333 %V 93 %X The use of polypropylene mesh devices for Pelvic Organ Prolapse (POP) spread rapidly during the last decade, yet our knowledge of the mesh-tissue interaction is far from complete. We aimed to perform a thorough pathological examination of explanted POP meshes and describe findings that may explain mechanisms of complications resulting in product excision. We report a spectrum of important findings, including nerve ingrowth, mesh deformation, involvement of detrusor muscle with neural ganglia, and polypropylene degradation. Analysis of these findings may improve and guide future treatment strategies. %P 549 - 552