@article{(Open Science Index):https://publications.waset.org/pdf/9996788,
	  title     = {Effect of Alginate and Surfactant on Physical Properties of Oil Entrapped Alginate Bead Formulation of Curcumin},
	  author    = {Arpa Petchsomrit and  Namfa Sermkaew and  Ruedeekorn Wiwattanapatapee},
	  country	= {},
	  institution	= {},
	  abstract     = {Oil entrapped floating alginate beads of curcumin were developed and characterized. Cremophor EL, Cremophor RH and Tween 80 were utilized to improve the solubility of the drug. The oil-loaded floating gel beads prepared by emulsion gelation method contained sodium alginate, mineral oil and surfactant. The drug content and % encapsulation declined as the ratio of surfactant was increased. The release of curcumin from 1% alginate beads was significantly more than for the 2% alginate beads. The drug released from the beads containing 25% of Tween 80 was about 70% while a higher drug release was observed with the beads containing Cremophor EL or Cremohor RH (approximately 90%). The developed floating beads of curcumin powder with surfactant provided a superior drug release than those without surfactant. Floating beads based on oil entrapment containing the drug solubilized in surfactants is a new delivery system to enhance the dissolution of poorly soluble drugs.
},
	    journal   = {International Journal of Pharmacological and Pharmaceutical Sciences},
	  volume    = {7},
	  number    = {12},
	  year      = {2013},
	  pages     = {864 - 868},
	  ee        = {https://publications.waset.org/pdf/9996788},
	  url   	= {https://publications.waset.org/vol/84},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 84, 2013},
	}