@article{(Open Science Index):https://publications.waset.org/pdf/9632, title = {Systholic Boolean Orthonormalizer Network in Wavelet Domain for Microarray Denoising}, author = {Mario Mastriani}, country = {}, institution = {}, abstract = {We describe a novel method for removing noise (in wavelet domain) of unknown variance from microarrays. The method is based on the following procedure: We apply 1) Bidimentional Discrete Wavelet Transform (DWT-2D) to the Noisy Microarray, 2) scaling and rounding to the coefficients of the highest subbands (to obtain integer and positive coefficients), 3) bit-slicing to the new highest subbands (to obtain bit-planes), 4) then we apply the Systholic Boolean Orthonormalizer Network (SBON) to the input bit-plane set and we obtain two orthonormal otput bit-plane sets (in a Boolean sense), we project a set on the other one, by means of an AND operation, and then, 5) we apply re-assembling, and, 6) rescaling. Finally, 7) we apply Inverse DWT-2D and reconstruct a microarray from the modified wavelet coefficients. Denoising results compare favorably to the most of methods in use at the moment. }, journal = {International Journal of Computer and Information Engineering}, volume = {2}, number = {9}, year = {2008}, pages = {3247 - 3258}, ee = {https://publications.waset.org/pdf/9632}, url = {https://publications.waset.org/vol/21}, bibsource = {https://publications.waset.org/}, issn = {eISSN: 1307-6892}, publisher = {World Academy of Science, Engineering and Technology}, index = {Open Science Index 21, 2008}, }