@article{(Open Science Index):https://publications.waset.org/pdf/8792,
	  title     = {Novel Anti-leukemia Calanone Compounds by Quantitative Structure-Activity Relationship AM1 Semiempirical Method},
	  author    = {Ponco Iswanto and  Mochammad Chasani and  Muhammad Hanafi and  Iqmal Tahir and  Eva Vaulina YD and  Harjono and  Lestari Solikhati and  Winkanda S. Putra and  Yayuk Yuliantini},
	  country	= {},
	  institution	= {},
	  abstract     = {Quantitative Structure-Activity Relationship (QSAR)
approach for discovering novel more active Calanone derivative as
anti-leukemia compound has been conducted. There are 6
experimental activities of Calanone compounds against leukemia cell
L1210 that are used as material of the research. Calculation of
theoretical predictors (independent variables) was performed by
AM1 semiempirical method. The QSAR equation is determined by
Principle Component Regression (PCR) analysis, with Log IC50 as
dependent variable and the independent variables are atomic net
charges, dipole moment (μ), and coefficient partition of noctanol/
water (Log P). Three novel Calanone derivatives that
obtained by this research have higher activity against leukemia cell
L1210 than pure Calanone.},
	    journal   = {International Journal of Chemical and Molecular Engineering},
	  volume    = {4},
	  number    = {5},
	  year      = {2010},
	  pages     = {367 - 372},
	  ee        = {https://publications.waset.org/pdf/8792},
	  url   	= {https://publications.waset.org/vol/41},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 41, 2010},
	}