@article{(Open Science Index):https://publications.waset.org/pdf/8261,
	  title     = {Optimization of Gentamicin Production: Comparison of ANN and RSM Techniques},
	  author    = {M.Rajasimman and  S.Subathra},
	  country	= {},
	  institution	= {},
	  abstract     = {In this work, statistical experimental design was
applied for the optimization of medium constituents for Gentamicin
production by Micromsonospora echinospora subs pallida (MTCC
708) in a batch reactor and the results are compared with the ANN
predicted values. By central composite design, 50 experiments are
carried out for five test variables: Starch, Soya bean meal, K2HPO4,
CaCO3 and FeSO4. The optimum condition was found to be: Starch
(8.9,g/L), Soya bean meal (3.3 g/L), K2HPO4 (0.8 g/L), CaCO3 (4
g/L) and FeSO4 (0.03 g/L). At these optimized conditions, the yield
of gentamicin was found to be 1020 mg/L. The R2 values were found
to be 1 for ANN training set, 0.9953 for ANN test set, and 0.9286 for
RSM.},
	    journal   = {International Journal of Chemical and Molecular Engineering},
	  volume    = {3},
	  number    = {3},
	  year      = {2009},
	  pages     = {163 - 168},
	  ee        = {https://publications.waset.org/pdf/8261},
	  url   	= {https://publications.waset.org/vol/27},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 27, 2009},
	}