%0 Journal Article
	%A M. Ramezani and  Gh. Amin and  E. Jalili
	%D 2010
	%J International Journal of Nutrition and Food Engineering
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 40, 2010
	%T Antinociceptive and Anti-inflammatory Effects of Hydroalcohol Extract of Vitex agnus castus Fruit
	%U https://publications.waset.org/pdf/6993
	%V 40
	%X In present study the effects of anti-inflammatory and
antinociceptive of vitex hydro-alcoholic extract were evaluated on
male mice. In inflammatory test mice were divided into 7 groups:
first group was control. The second group, positive control group,
received dexamethasone (15 mg/kg) and the other five groups
received different doses of hydroalcohol extract of Vitex fruit (265,
365, 465, 565, and 665 mg/kg). The inflammation was caused by
xylene-induced ear edema. Formalin test was used for evaluation of
antinociceptive effect of extract. In this test, mice were divided into 7
groups: control, morphine (10mg/kg) as positive control group, and
Vitex extract groups ((265, 365, 465, 565, and 665 mg/kg). All drugs
were administered intrapritoneally, 30 min before each test. The data
were analyzed using one-way ANOVA followed by Tukey-kramer
multiple comparison test. Results have shown significant antiinflammatory
effects of extract at all dosed as compared with control
	%P 214 - 216