@article{(Open Science Index):https://publications.waset.org/pdf/6562,
	  title     = {Chitosan/Casein Microparticles: Preparation, Characterization and Drug Release Studies},
	  author    = {Selvakumar Dhanasingh and  Shunmuga Kumar Nallaperumal},
	  country	= {},
	  institution	= {},
	  abstract     = {Microparticles carrier systems made from naturally occurring polymers based on chitosan/casein system appears to be a promising carrier for the sustained release of orally and parenteral administered drugs. In the current study we followed a microencapsulation technique based aqueous coacervation method to prepare chitosan/casein microparticles of compositions 1:1, 1:2 and 1:5 incorporated with chloramphenicol. Glutaraldehyde was used as a chemical cross-linking agent. The microparticles were prepared by aerosol method and studied by optical microscopy, infrared spectroscopy, thermo gravimetric analysis, swelling studies and drug release studies at various pH. The percentage swelling of the polymers are found to be in the order pH 4 > pH 10 > pH 7 and the increase in casein composition decrease the swelling percentage. The drug release studies also follow the above order.
},
	    journal   = {International Journal of Bioengineering and Life Sciences},
	  volume    = {4},
	  number    = {8},
	  year      = {2010},
	  pages     = {476 - 480},
	  ee        = {https://publications.waset.org/pdf/6562},
	  url   	= {https://publications.waset.org/vol/44},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 44, 2010},
	}