@article{(Open Science Index):https://publications.waset.org/pdf/5731, title = {X-ray Crystallographic Analysis of MinC N-Terminal Domain from Escherichia coli}, author = {Jun Yop An and Kyoung Ryoung Park and Jung-Gyu Lee and Hyung-Seop Youn and Jung-Yeon Kang and Gil Bu Kang and Soo Hyun Eom}, country = {}, institution = {}, abstract = {MinC plays an important role in bacterial cell division system by inhibiting FtsZ assembly. However, the molecular mechanism of the action is poorly understood. E. coli MinC Nterminus domain was purified and crystallized using 1.4 M sodium citrate pH 6.5 as a precipitant. X-ray diffraction data was collected and processed to 2.3 Å from a native crystal. The crystal belonged to space group P212121, with the unit cell parameters a = 52.7, b = 54.0, c = 64.7 Å. Assuming the presence of two molecules in the asymmetric unit, the Matthews coefficient value is 1.94 Å3 Da-1, which corresponds to a solvent content of 36.5%. The overall structure of MinCN is observed as a dimer form through anti-parallel ß-strand interaction.}, journal = {International Journal of Bioengineering and Life Sciences}, volume = {4}, number = {8}, year = {2010}, pages = {516 - 519}, ee = {https://publications.waset.org/pdf/5731}, url = {https://publications.waset.org/vol/44}, bibsource = {https://publications.waset.org/}, issn = {eISSN: 1307-6892}, publisher = {World Academy of Science, Engineering and Technology}, index = {Open Science Index 44, 2010}, }