TY - JFULL AU - Vipin Saini and Sunil Kamboj and Suman Bala and A. Pandurangan PY - 2013/10/ TI - Novel Process Formulation of Multiple Unit Tablet of Pantoprazole T2 - International Journal of Pharmacological and Pharmaceutical Sciences SP - 573 EP - 579 VL - 7 SN - 1307-6892 UR - https://publications.waset.org/pdf/16694 PU - World Academy of Science, Engineering and Technology NX - Open Science Index 81, 2013 N2 - The present invention relates to multiple-unit tablet dosage forms, which is composed of several subunits (multiparticulates/pellets). Each small multiparticulate further composed of many layers. Some layer contains drug substance; others are rate controlling polymer. The resulting multiple-unit tablet dosage forms of pantoprazole were satisfactory fabricated. Pelletization technique has some advantages over coated tablet formulation. In coated tablet the coating may be damaged and a pinhole possibly formed that would result in increased release of drug in stomach and may be deactivated in stomach juices. If the coat of some pellets may be damaged that would not affect the release properties of the multiple-unit tablet. Hence they are beneficial in this aspect. The results confirmed the successful preparation of stable and bioequivalent once daily controlled release multiple-unit tablets of pantoprazole. ER -