@article{(Open Science Index):https://publications.waset.org/pdf/16058,
	  title     = {Synthesis and Characterization of PEG-Silane Functionalized Iron Oxide Nanoparticle as MRI T2 Contrast Agent},
	  author    = { Mu-Jen Young and  Cheng-Yen Wu and  Wen-Yuan Hsieh},
	  country	= {},
	  institution	= {},
	  abstract     = {Iron oxide nanoparticle was synthesized by reactive-precipitation method followed by high speed centrifuge and phase transfer in order to stabilized nanoparticles in the solvent. Particle size of SPIO was 8.2 nm by SEM, and the hydraulic radius was 17.5 nm by dynamic light scattering method. Coercivity and saturated magnetism were determined by VSM (vibrating sample magnetometer), coercivity of nanoparticle was lower than 10 Hc, and the saturated magnetism was higher than 65 emu/g. Stabilized SPIO was then transferred to aqueous phase by reacted with excess amount of poly (ethylene glycol) (PEG) silane. After filtration and dialysis, the SPIO T2 contrast agent was ready to use. The hydraulic radius of final product was about 70~100 nm, the relaxation rates R2 (1/T2) measured by magnetic resonance imaging (MRI) was larger than 200(sec-1).
},
	    journal   = {International Journal of Biomedical and Biological Engineering},
	  volume    = {7},
	  number    = {8},
	  year      = {2013},
	  pages     = {444 - 446},
	  ee        = {https://publications.waset.org/pdf/16058},
	  url   	= {https://publications.waset.org/vol/80},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 80, 2013},
	}