%0 Journal Article
	%A Shujaat A. Khan and  Ghulam Murtaza
	%D 2012
	%J International Journal of Pharmacological and Pharmaceutical Sciences
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 63, 2012
	%T Release Behavior of Biodegradable and Nonbiodegradable Polymeric Microparticles Loaded with Nimesulide
	%U https://publications.waset.org/pdf/15484
	%V 63
	%X This presentation narrates the comparative analysis of
the dissolution data nimesulide microparticles prepared with
ethylcellulose, hydroxypropyl methylcellulose, chitosan and
Poly(D,L-lactide-co-glycolide) as polymers. The analysis of release
profiles showed that the variations noted in the release behavior of
nimesulide from various microparticulate formulations are due to the
nature of used polymer. In addition, maximum retardation in the
nimesulide release was observed with HPMC (floating particles).
Thus HPMC miacroparticles may be preferably employed for
sustained release dosage form development.
	%P 52 - 54