%0 Journal Article %A Nelly К. Akhmatova and Оlga V. Lebedinskaya and Stanislav G. Markushin and Elvin А. Akhmatov and Lidiya A. Geiderova and Еlena А. Lebedinskaya and Vera M. Axenova and Аnatoliy P. Godovalov %D 2012 %J International Journal of Medical and Health Sciences %B World Academy of Science, Engineering and Technology %I Open Science Index 72, 2012 %T Features of the Immune Response in Mice were Immunized with Polio Vaccine in Combination with Chitosan Preparations as Adjuvants %U https://publications.waset.org/pdf/15227 %V 72 %X The study of cytokine expression in mice under the influence of inactivated poliovirus and Imovaks polio vaccine in combination with derivatives of chitosan shows various kinds of processes. There is a significant increase in IL-12 in the serum of immunized animals, which should stimulate the production of IFN-γ NK-cells and T-cells and polarize the immune response to Th1 type. Thus, the derivatives of chitosan can promote cell component of the immune response, providing a full antiviral immunity. %P 743 - 745