%0 Journal Article %A Sanae Kaewnopparat and Nattha Kaewnopparat %D 2009 %J International Journal of Pharmacological and Pharmaceutical Sciences %B World Academy of Science, Engineering and Technology %I Open Science Index 31, 2009 %T Formulation and Evaluation of Vaginal Suppositories Containing Lactobacillus %U https://publications.waset.org/pdf/15159 %V 31 %X The objective of this study was to develop vaginal suppository containing lactobacillus. Four kinds of vaginal suppositories containing Lactobacillus paracasei HL32 were formulated: 1) a conventional suppository with Witepsol H-15 as a base, 2) a conventional suppository with mixed polyethylene glycols (PEGs) as a base, 3) a hollow-type suppository with Witepsol H-15 as a base and 4) a hollow-type suppository with mixed PEGs as a base. The release studies demonstrated that the hollow-type suppository with mixed PEGs as the base gave the highest release of L. paracasei HL32 and was microbiological stable after storage at 2- 8°C over the period of 3 months. %P 117 - 120