%0 Journal Article %A Zhang Linan and Jihwan Song and Dongchoul Kim %D 2010 %J International Journal of Biomedical and Biological Engineering %B World Academy of Science, Engineering and Technology %I Open Science Index 44, 2010 %T A Study on Cancer-Cell Invasion Based On the Diffuse Interface Model %U https://publications.waset.org/pdf/13944 %V 44 %X In this study, a three-dimensional haptotaxis model to simulate the migration of a population of cancer cells has been proposed. The invasion of cancer cells is related with the hapto-attractant and the effect of the interface energies between the cells and the ECM. The diffuse interface model, which incorporates the haptotaxis mechanism and interface energies, is employed. The semi-implicit Fourier spectral scheme is adopted for efficient evaluation of the simulation. The simulation results thoroughly reveal the dynamics of cancer-cell migration. %P 346 - 349