%0 Journal Article %A Brajesh Kumar Jha and Neeru Adlakha and M. N. Mehta %D 2011 %J International Journal of Physical and Mathematical Sciences %B World Academy of Science, Engineering and Technology %I Open Science Index 51, 2011 %T Finite Volume Model to Study the Effect of Buffer on Cytosolic Ca2+ Advection Diffusion %U https://publications.waset.org/pdf/13219 %V 51 %X Calcium [Ca2+] is an important second messenger which plays an important role in signal transduction. There are several parameters that affect its concentration profile like buffer source etc. The effect of stationary immobile buffer on Ca2+ concentration has been incorporated which is a very important parameter needed to be taken into account in order to make the model more realistic. Interdependence of all the important parameters like diffusion coefficient and influx over [Ca2+] profile has been studied. Model is developed in the form of advection diffusion equation together with buffer concentration. A program has been developed using finite volume method for the entire problem and simulated on an AMD-Turion 32-bit machine to compute the numerical results. %P 315 - 318