%0 Journal Article %A Chun-Wei Tung and Chyn Liaw and Shinn-Jang Ho and Shinn-Ying Ho %D 2010 %J International Journal of Biomedical and Biological Engineering %B World Academy of Science, Engineering and Technology %I Open Science Index 41, 2010 %T Prediction of Protein Subchloroplast Locations using Random Forests %U https://publications.waset.org/pdf/12938 %V 41 %X Protein subchloroplast locations are correlated with its functions. In contrast to the large amount of available protein sequences, the information of their locations and functions is less known. The experiment works for identification of protein locations and functions are costly and time consuming. The accurate prediction of protein subchloroplast locations can accelerate the study of functions of proteins in chloroplast. This study proposes a Random Forest based method, ChloroRF, to predict protein subchloroplast locations using interpretable physicochemical properties. In addition to high prediction accuracy, the ChloroRF is able to select important physicochemical properties. The important physicochemical properties are also analyzed to provide insights into the underlying mechanism. %P 336 - 340