Brajesh Kumar Jha and Neeru Adlakha and M. N. Mehta
Finite Volume Model to Study The Effect of Voltage Gated Ca2 Channel on Cytosolic Calcium Advection Diffusion
1379 - 1383
2011
5
8
International Journal of Mathematical and Computational Sciences
https://publications.waset.org/pdf/11931
https://publications.waset.org/vol/56
World Academy of Science, Engineering and Technology
Mathematical and computational modeling of calcium
signalling in nerve cells has produced considerable insights into how
the cells contracts with other cells under the variation of biophysical
and physiological parameters. The modeling of calcium signaling in
astrocytes has become more sophisticated. The modeling effort has
provided insight to understand the cell contraction. Main objective
of this work is to study the effect of voltage gated (Operated)
calcium channel (VOC) on calcium profile in the form of advection
diffusion equation. A mathematical model is developed in the form
of advection diffusion equation for the calcium profile. The model
incorporates the important physiological parameter like diffusion
coefficient etc. Appropriate boundary conditions have been framed.
Finite volume method is employed to solve the problem. A program
has been developed using in MATLAB 7.5 for the entire problem
and simulated on an AMDTurion 32bite machine to compute the
numerical results.
Open Science Index 56, 2011