TY - JFULL
AU - Brajesh Kumar Jha and Neeru Adlakha and M. N. Mehta
PY - 2011/9/
TI - Finite Volume Model to Study The Effect of Voltage Gated Ca2+ Channel on Cytosolic Calcium Advection Diffusion
T2 - International Journal of Mathematical and Computational Sciences
SP - 1378
EP - 1383
VL - 5
SN - 1307-6892
UR - https://publications.waset.org/pdf/11931
PU - World Academy of Science, Engineering and Technology
NX - Open Science Index 56, 2011
N2 - Mathematical and computational modeling of calcium
signalling in nerve cells has produced considerable insights into how
the cells contracts with other cells under the variation of biophysical
and physiological parameters. The modeling of calcium signaling in
astrocytes has become more sophisticated. The modeling effort has
provided insight to understand the cell contraction. Main objective
of this work is to study the effect of voltage gated (Operated)
calcium channel (VOC) on calcium profile in the form of advection
diffusion equation. A mathematical model is developed in the form
of advection diffusion equation for the calcium profile. The model
incorporates the important physiological parameter like diffusion
coefficient etc. Appropriate boundary conditions have been framed.
Finite volume method is employed to solve the problem. A program
has been developed using in MATLAB 7.5 for the entire problem
and simulated on an AMD-Turion 32-bite machine to compute the
numerical results.
ER -