Detection and Correction of Ectopic Beats for HRV Analysis Applying Discrete Wavelet Transforms
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 32804
Detection and Correction of Ectopic Beats for HRV Analysis Applying Discrete Wavelet Transforms

Authors: Desmond B. Keenan

Abstract:

The clinical usefulness of heart rate variability is limited to the range of Holter monitoring software available. These software algorithms require a normal sinus rhythm to accurately acquire heart rate variability (HRV) measures in the frequency domain. Premature ventricular contractions (PVC) or more commonly referred to as ectopic beats, frequent in heart failure, hinder this analysis and introduce ambiguity. This investigation demonstrates an algorithm to automatically detect ectopic beats by analyzing discrete wavelet transform coefficients. Two techniques for filtering and replacing the ectopic beats from the RR signal are compared. One technique applies wavelet hard thresholding techniques and another applies linear interpolation to replace ectopic cycles. The results demonstrate through simulation, and signals acquired from a 24hr ambulatory recorder, that these techniques can accurately detect PVC-s and remove the noise and leakage effects produced by ectopic cycles retaining smooth spectra with the minimum of error.

Keywords: Heart rate variability, vagal tone, sympathetic, parasympathetic, wavelets, ectopic beats, spectral analysis.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1074673

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2012

References:


[1] M. H. Crawford, S. Bernstein, P. Deedwania, "ACC/AHA guidelines for ambulatory electrocardiography," Circulation, vol. 100, pp. 886-893, 1999.
[2] N. Montano, T. Gnecchi Ruscone, A. Porta, F. Lombardi, M. Pagani, A. Malliani, "Power spectrum analysis of heart rate variability to assess the changes in sympathovagal balance during graded orthostatic tilt," Circulation, vol. 90, pp. 1826-1831, 1994.
[3] A. Malliani, M. Pagani, F. Lombardi, S. Cerruti, "Cardiovascular neural regulation explored in the frequency domain," Circulation, vol. 84, pp. 482-492, 1991.
[4] M. Pagani, N. Montano, A. Porta, "Relationship between spectral components of cardiovascular variabilities and direct measures of muscle sympathetic nerve activity in humans," Circulation, vol. 95, pp. 1441-1448, 1997.
[5] G. Paolisso, D. Manzella, N. Ferrara, et al. "Glucose Ingestion Affects Cardiac ANS in Healthy Subjects with Different Amounts of Body Fat," American Journal of Physiology, vol. 273, pp. E471-E478, 1997.
[6] A. Ravogli, G. Parati, E. Tortorici et al, "Early cardiovascular alterations in young obese subjects: evidence from 24-hour blood pressure and heart rate monitoring," Europ. Heart J., vol. 98, pp. 3405A, 1998.
[7] R. M. Carney, J. A. Blumenthal, P. K. Stein, L. Watkins, D. Catellier, L. F. Berkman, S. M. Czajkowski, C. O'Connor, P. H. Stone, K. E. Freedland, "Depression, Heart Rate Variability, and Acute Myocardial Infarction," Circulation, vol. 104, no. 17, pp. 2024 - 2028, 2001.
[8] P. Grossman, J. A. Van Beek, "A Comparison of Three Quantification Methods for Estimation of Respiratory Sinus Arrhythmia," Psychophysiology, vol. 27, no. 6, pp. 702-714, 1990.
[9] K. Kotani, I. Hidaka, Y. Yamamoto, S. Ozono, "Analysis of Respiratory Sinus Arrhythmia with Respect to Respiratory Phase," Methods of Information in Medicine, vol. 39, pp. 153-156, 2000.
[10] J. Mateo, P. Gasc├│n, L. Lasaosa, "Analysis of Heart Rate Variability in the Presence of Ectopic Beats Using the Heart Timing Signal," IEEE Transactions on Biomedical Engineering, vol. 50, no. 3, pp. 334-343, 2003.
[11] M. A. Murda'h,, W. J. McKenna, A. J. Camm, "Repolarization Alternans: Techniques, Mechanisms, and Cardiac Vulnerability," Pacing Clinical Electrophysioly, vol. 20, pp. 2641-2657, 1997.
[12] P. Laguna, R. Jané, P. Caminal, "Adaptive estimation of QRS complex by the Hermite model for classification and ectopic beat detection," Medical and Biological Engineering and Computing, vol. 34, pp. 58-68, 1996.
[13] M. A. Salo, T. Seppänen, H. V. Huikuri, "Ectopic Beats in Heart Rate Variability Analysis: Effects of Editing on Time and Frequency Domain Measures," Annals of Noninvasive Electrocardiology, vol. 6, no. 1, pp. 5-17, 2001.
[14] K. Konno and J. Mead, "Measurement of the separate volume changes of rib cage and abdomen during breathing," J. Appl. Physiol., vol. 22, pp. 407-422, 1967.
[15] J. Sackner, A. Nixon, B. Davis, N. Atkins, and M. Sackner, "Noninvasive measurement of ventilation during exercise using a respiratory inductive plethysmograph. I," Am. Rev. Respir. Dis., vol. 122, pp. 867- 871, 1980.
[16] J. A. Adams, I. A. Zabaleta, D. Stroh, M. A. Sackner, "Measurement of breath amplitudes: comparison of three noninvasive respiratory monitors to integrated pneumotachograph," Pediatr. Pulmonol., vol. 16, pp. 254- 258, 1993.
[17] M. A. Sackner, and B. P. Krieger, "Non-invasive respiratory monitoring," In: Heart-Lung Interactions in Health and Disease, edited by S.M. Scharf, and S. S. Cassidy, New York: Marcel Dekker, pp. 663- 805, 1989.
[18] M. A. Sackner et al, "Calibration of respiratory inductive plethyomograph during natural breathing," J. Appl. Physiol. vol. 66, pp. 410-420, 1989.
[19] M. A. Sackner et al, "Qualitative diagnostic calibration technique," J. Appl. Physiol., vol. 87, 869-870, 1999.
[20] J. Pan and W. J. Tompkins, "A real-time QRS detection algorithm," IEEE Trans. Biomed. Eng., vol. 32, no. 3, pp. 230-236, 1985..
[21] P. D. Welch, "The Use of Fast Fourier Transform for the Estimation of Power Spectra: A Method Based on Time Averaging Over Short, Modified Periodograms," IEEE Trans. Audio Electroacoustics, vol. AU- 15, pp. 70-73, 1967.
[22] A. J. Camm, M. Malik, "Heart Rate Variability: Standards of Measurement, Physiological Interpretation and Clinical Use," Task Force of the Working Groups on Arrhythmias and Computers in Cardiology of the ESC and the North American Society of Pacing and Electrophysiology (NASPE). European Heart Journal, vol. 93, pp. 1043-1065, 1996.
[23] I. Daubechies, "Orthogonal bases of compactly supported wavelets," Communications on Pure and Applied Mathematics, vol. 41, pp. 909- 996, 1988.
[24] D. L. Donoho, I. M. Johnstone, "Wavelet Shrinkage: Asymptopia?," Journal of the Royal Statistical Societ, Series B, vol. 57, pp. 301-369, 1995.
[25] D. L. Donoho, I. M. Johnstone, "Ideal time-frequency denoising, Technical Report," Department of Statistics, Standford University, 1994.
[26] D. L. Donoho, I. M. Johnstone, "Ideal Spatial Adaptation via Wavelet Shrinkage," Biometrika, vol. 81, pp. 425-455, 1994.
[27] D. L. Donoho, "De-noising by Soft Thresholding," IEEE Transactions on Information Technology, vol. 41, pp. 613-627, 1995.