S. Mohammadzadehmoghadam and Y. Dong
Electrospinning and Characterization of Silk FibroinGelatin Nanofibre Mats
429 - 432
2018
12
8
International Journal of Materials and Metallurgical Engineering
https://publications.waset.org/pdf/10009441
https://publications.waset.org/vol/140
World Academy of Science, Engineering and Technology
In this study, Bombyx mori silk fibroingelatin (SFGT) nanocomposite with different GT ratio (SFGT 1000, 9010 and 7030) were prepared by electrospinning process and crosslinked with glutaraldehyde (GA) vapor. Properties of crosslinked SFGT nanocomposites were investigated by scanning electron microscopy (SEM), mechanical test, water uptake capacity (WUC) and porosity. From SEM images, it was found that fiber diameter increased as GT content increased. The results of mechanical test indicated that the SFGT 7030 nanocomposites had both the highest Young’s modulus of 342 MPa and the highest tensile strength of about 14 MPa. However, porosity and WUC decreased from 62 and 405 for pristine SF to 47 and 232 for SFGT 7030, respectively. This behavior can be related to higher degree of crosslinking as GT ratio increased which altered the structure and physical properties of scaffolds. This study showed that incorporation of GT into SF nanofibers can enhance mechanical properties of resultant nanocomposite, but the GA treatment should be optimized to control and finetune other properties to warrant their biomedical application.
Open Science Index 140, 2018