@article{(Open Science Index):https://publications.waset.org/pdf/10009050, title = {Evaluation of TRIS-DMA-NVP Hydrogels for Making Silicone-Based Contact Lenses}, author = {N. P. D. Tran and H. Q. D. Nguyen and M. C. Yang}, country = {}, institution = {}, abstract = {In this study, contact lenses were prepared through the polymerization of tris-(trimethyl-silyl-propyl-methacrylate) (TRIS), N,N-dimethylacrylamide (DMA), N-vinylpyrrolidone (NVP), and cross-linked with ethylene glycol dimethylacrylate (EGDMA). The equilibrium water content (EWC), oxygen permeability (Dk), light transmittance, and in vitro cytotoxicity of TRIS-DMA-NVP with various ratios were measured. The results showed that the EWC increased while the Dk decreased with the increase of NVP content. For the sample with 25 wt% NVP, the EWC attained 53% whereas the Dk decreased to 46 barrers. All these lenses exhibited light transmittance over than 95%. In addition, all these lenses exhibited no inhibition to the growth of L292 fibroblasts. Thus, this study showed that TRIS-DMA-NVP can be applicable for making contact lens. }, journal = {International Journal of Chemical and Molecular Engineering}, volume = {12}, number = {3}, year = {2018}, pages = {183 - 186}, ee = {https://publications.waset.org/pdf/10009050}, url = {https://publications.waset.org/vol/135}, bibsource = {https://publications.waset.org/}, issn = {eISSN: 1307-6892}, publisher = {World Academy of Science, Engineering and Technology}, index = {Open Science Index 135, 2018}, }