Surveillance for African Swine Fever and Classical Swine Fever in Benue State, Nigeria

Authors: A. Asambe, A. K. B. Sackey, L. B. Tekdek

Abstract:

A serosurveillance study was conducted to detect the presence of antibodies to African swine fever virus (ASFV) and Classical swine fever virus in pigs sampled from piggeries and Makurdi central slaughter slab in Benue State, Nigeria. 416 pigs from 74 piggeries across 12 LGAs and 44 pigs at the Makurdi central slaughter slab were sampled for serum. The sera collected were analysed using Indirect Enzyme Linked Immunosorbent Assay (ELISA) test kit to test for antibodies to ASFV, while competitive ELISA test kit was used to test for antibodies to CSFV. Of the 416 pigs from piggeries and 44 pigs sampled from the slaughter slab, seven (1.7%) and six (13.6%), respectively, tested positive to ASFV antibodies and was significantly associated (p < 0.0001). Out of the 12 LGAs sampled, Obi LGA had the highest ASFV antibody detection rate of (4.8%) and was significantly associated (p < 0.0001). None of the samples tested positive to CSFV antibodies. The study concluded that antibodies to CSFV were absent in the sampled pigs in piggeries and at the Makurdi central slaughter slab in Benue State, while antibodies to ASFV were present in both locations; hence, the need to keep an eye open for CSF too since both diseases may pose great risk in the study area. Further studies to characterise the ASFV circulating in Benue State and investigate the possible sources is recommended. Routine surveillance to provide a comprehensive and readily accessible data base to plan for the prevention of any fulminating outbreak is also recommended.

Keywords: African swine fever, classical swine fever, piggery, slaughter slab, surveillance.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1316185

References:

[1] Abwage S. A, Umaru G. A., Musa Y. B., Adamu Z., Akensire U. A., Njobdi A. B and Bello O. A, (2015). Detection of African swine fever virus (ASFV) antibodies in pigs in Taraba state north east Nigeria. Sokoto Journal of Veterinary Sciences 13: 20-25.
[2] Aiki-Raji C. O., Adebiyi A. I., Adeyemo I. A., Fagbohun O. A and Oluwayelu D. O. (2014). Seroprevalence of Classical Swine Fever Antibodies in Slaughtered Pigs at Bodija Municipal Abattoir, Ibadan, South West Nigeria. European Journal of Scientific Research, 126(4): 402-407.
[3] Ate, I. U and Oyedipe, E.O. (2011). Sow Reproductive Performance in Institutional Herds in Benue State, Nigeria. Journal of Reproduction and Infertility, 2(2): 24-31.
[4] Awosanya E. J., Olugasa B., Ogundipe G and Grohn Y. P. (2015): Seroprevalence and risk factors associated with African swine fever on pig farms in southwest Nigeria. BMC Veterinary Research, 11:133.
[5] Babalobi O. O, Ayoade G. O., Olugasa B. O., Oluwayelu D. O and Oyedela O. (2003). Differential diagnosis of a swine epizootic of unknown aetiology in Ibadan, Oyo State, Nigeria. Isreal Journal of Veterinary Medicine, 58(2/3): 86-89.
[6] Babalobi O. O, Olugasa B. O, Oluwayelu D. O, Ijagbone I. F., Ayoade G. O. and Agbede S.A (2007). Analysis and evaluation of mortality losses of the 2001 African swine fever outbreak, Ibadan, Nigeria. Tropical Animal Health Production, 39(7): 533-542.
[7] Carrillo C., Borca M. V., Afonso C. L., Onisk D.V and Rock D. L. (1994). Long-term persistent infection of swine monocytes/macrophages with African swine fever virus. Journal of Virology, 68: 580-583.
[8] Costard, S., Wieland, B., de Glanville, W., Jori, F., Rowlands, R., Vosloo, W., Roger, F., Pfeiffer, D. U and Dixon, L. K. (2009b). African swine fever: how can global spread be prevented? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 364(1530): 2683-2696.
[9] El-Hicheri, K. (1998). Emergency assistance on control and eradication of an outbreak of African swine fever in Western Nigeria. Report of the FAO Consultancy Mission to Nigeria. TCP/NIR/7822(E). FAO, Rome.
[10] Fasina F. O., Agbaje, M., Ajani, F. L., Talabi, O. A., Lazarus, D. D., Gallardo, C., Thompson, P. N and Bastos, A. D. S. (2012). Risk factors for farm-level African swine fever infection in major pig-producing areas in Nigeria, 1997-2011. Preventive Veterinary Medicine, 107(1-2): 65-75.
[11] Fasina, F. O., Shamaki D., Makinde, A. A., Lombin, L. H., Lazarus, D. D., Rua’i S. A., Adamu, S. S., Agom D., Pelayo, V., Soler, A., Simon A., Adedeji, A. J., Yakubu M. B., Mantip S., Benshak, A. J., Okeke, I., Anagor, P., Mandeng, D. C., Akanbi, B. O., Ajibade, A. A., Faramade, I., Kazeem, M. M., Enurah, L. U., Bishop, R., Anvhuelo, R., Martin, J. H and Gallardo, C. (2010). Surveillance of African swine fever in Nigeria, 2006-2009. Transboundary Emerging Diseases, 57(4): 244-253.
[12] Fasina, F. O., Shamaki, D., Makinde, A. A., Pitt, A.S.F. (2009). Field surveillance and laboratory diagnoses of African swine fever in Nigeria (IAEA-CN-174-151). Book of Synopses, FAO/IAEA International Symposium on Sustainable Improvement of Animal Production and Health, 8-11 June 2009, Vienna, Austria, pp. 301-302.
[13] Food Agricultural Organization of the United Nations. (1998d). African swine fever in Nigeria hits rural poor. News and Highlights. Retrieved March 25, 2016 from http://www.fao.org/NEWS/1998/981201-e.htm.
[14] Food Agricultural Organization of the United Nations. (2005). Animal genetic resources and resistance to disease. In: The state of agricultural biodiversity in the livestock sector. pp. 109. Retrieved June 10, 2017, from ftp://ftp.fao.org/docrep/fao/010/a1250e/a1250e05.pdf.
[15] Kperebeyi J. I and Amotsuka P. (2010). An outbreak of African Swine Fever (ASF) in Delta State Polytechnic Piggery Farm, Ozoro, Nigeria. African Journal of General Agriculture, 6(1): 25-29.
[16] Lammers P. J., Stender D. R and Honeyman M. S. (2007). Replacement gilts and sow longevity. Reproduction and genetics. IPIC NPP, 420: 1-3.
[17] Odemuyiwa S. O, Adebayo I. A., Ammerlaan W., Alaka O. O., Oyedele O. I., Soyelu K. O, Olaleye, D. O., Otesile, E. B and Muller, C. P. (2000). An outbreak of African swine fever in Nigeria: virus isolation and molecular characterization of VP72 gene of a first isolate from West Africa. Virus Gene, 20(2): 139-142.
[18] Olugasa B. O. (2007): Serological evidence of African swine fever virus infection in commercial pig herds in South west Nigeria. African Journal of Livestock Extension, 5(1): 61-66.
[19] Owolodun, O. A., Yakubu, B., Antiabong, J. F., Ogedengbe, O. E., Luka, P. D and Audu, J. B. (2010c). Spatio-temporal dynamics of African swine fever outbreaks in Nigeria, 2002–2007. Transbound Emerging Diseases, 57(5): 330-339.
[20] Penrith, M. L., Vosloo W and Jori F., (2013). African swine fever virus eradication in Africa. Journal of Virus Research, 173(1): 228-246.
[21] Penrith, M. L., Vosloo, W and Mather, C. (2011). Classical Swine Fever (hog cholera): review of aspects relevant to control. Transboundry Emerging Disease, 58(3): 187-196.
[22] Petrov A and Salzungen B. (2015). Design and validation of optimized tools for Classical and African swine fever surveillance and pathogenesis research. Inaugural- Dissertation zur Erlangung der Doktorwürde der Tierärztlichen Fakultät der Ludwig-Maximilians-Universität München.
[23] Randriamparany, T., Grenier, A., Tourette, I., Maharavo Rahantamalala, C., Rousset, D and Lancelot, R. (2005). Epidemiological situation of African swine fever in Lake Alaotra Region (Madagascar) and possible consequences on the organization of disease control and surveillance. Revue d Elevage et de Medecine Veterinaire des Pays Tropicaux, 58: 15-20.
[24] Saka J. O., Adesehinwa, A. O. K and Ajala, M. K. (2010). Incidence of African swine fever disease and its associated implications on pig production in Lagos State, Nigeria. Bulgarian Journal of Agricultural Science, 16(1): 80-90.