%0 Journal Article
	%A J. Fernandez and  N. Aguilar and  R. Fernandez de Canete and  J. C. Ramos-Diaz
	%D 2017
	%J International Journal of Bioengineering and Life Sciences
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 129, 2017
	%T Causal Modeling of the Glucose-Insulin System in Type-I Diabetic Patients
	%U https://publications.waset.org/pdf/10007938
	%V 129
	%X In this paper, a simulation model of the glucose-insulin system for a patient undergoing diabetes Type 1 is developed by using a causal modeling approach under system dynamics. The OpenModelica simulation environment has been employed to build the so called causal model, while the glucose-insulin model parameters were adjusted to fit recorded mean data of a diabetic patient database. Model results under different conditions of a three-meal glucose and exogenous insulin ingestion patterns have been obtained. This simulation model can be useful to evaluate glucose-insulin performance in several circumstances, including insulin infusion algorithms in open-loop and decision support systems in closed-loop.

	%P 672 - 677