H. Binti Ya’akob and C. Siew Chin and A. Abd Aziz and I. Ware and M. Fauzi Abd Jalil and N. Rashidah Ahmed and R. Sabtu
Effect of Span 60, Labrasol, and Cholesterol on Labisia pumila Loaded Niosomes Quality
521 - 524
2017
11
7
International Journal of Biotechnology and Bioengineering
https://publications.waset.org/pdf/10007586
https://publications.waset.org/vol/127
World Academy of Science, Engineering and Technology
Labisia pumila (LP) plant extract has the potential to be applied in cosmeceutical products due to its antiphotoaging properties. The main purpose of this study was to improve transdermal delivery of LP by encapsulating LP in niosomes. Niosomes loaded LPs were prepared by coacervation phase separation method using nonionic surfactant (Span 60), labrasol, and cholesterol. The optimum formula obtained were Span 60, labrasol and cholesterol at the mole ratio of 614. At the optimum formulation, the niosome obtained significantly improved the quality of transdermal penetration of LP compared to free LP.
Open Science Index 127, 2017