TY - JFULL AU - H. Binti Ya’akob and C. Siew Chin and A. Abd Aziz and I. Ware and M. Fauzi Abd Jalil and N. Rashidah Ahmed and R. Sabtu PY - 2017/8/ TI - Effect of Span 60, Labrasol, and Cholesterol on Labisia pumila Loaded Niosomes Quality T2 - International Journal of Biotechnology and Bioengineering SP - 520 EP - 524 VL - 11 SN - 1307-6892 UR - https://publications.waset.org/pdf/10007586 PU - World Academy of Science, Engineering and Technology NX - Open Science Index 127, 2017 N2 - Labisia pumila (LP) plant extract has the potential to be applied in cosmeceutical products due to its anti-photoaging properties. The main purpose of this study was to improve transdermal delivery of LP by encapsulating LP in niosomes. Niosomes loaded LPs were prepared by coacervation phase separation method using non-ionic surfactant (Span 60), labrasol, and cholesterol. The optimum formula obtained were Span 60, labrasol and cholesterol at the mole ratio of 6:1:4. At the optimum formulation, the niosome obtained significantly improved the quality of transdermal penetration of LP compared to free LP. ER -