The main objective of the present article is to explore the state of mixed convection nanofluid flow of gyrotactic microorganisms from an isothermal vertical wedge in porous medium. In our pioneering investigation, the easiest possible boundary conditions have been employed, in other words when the temperature, the nanofluid and motile microorganisms’ density have been considered to be constant on the wedge wall. Adding motile microorganisms to the nanofluid tends to enhance microscale mixing, mass transfer, and improve the nanofluid stability. Upon the Oberbeck–Boussinesq approximation and non-similarity transmutation, the paradigm of nonlinear equations are obtained and tackled numerically by using the R.K. Gill and shooting methods to obtain the dimensionless velocity, temperature, nanoparticle concentration and motile microorganisms density together with the reduced Sherwood, Nusselt, and numbers. Bioconvection parameters have strong effect upon the motile microorganism, heat, and volume fraction of nanoparticle transport rates. In the case when bioconvection is neglected, the obtained computations were found in very good agreement with the previous published data.<\/p>\r\n","references":"[1]\tP. Keblinski, S.R. Phillpot, S.U.-S. Choi, J.A. Eastman, Mechanisms of heat flow in suspensions of nano-sized particles (nanofluids), Int. J. Heat Mass Transfer 45 (4) (2002) 855\u2013863.\r\n[2]\tU. S. U. Choi, Enhancing thermal conductivity of fluids with nanoparticle. In: Siginer, D.A., Wang H.P. (eds.), Developments and Applications of Non-Newtonian Flows, ASME FED, 231\/MD 66 (1995) 99\u2013105.\r\n[3]\tA. Mahdy, S. E. Ahmed, Laminar free convection over a vertical wavy surface embedded in a porous medium saturated with a nanofluid. Transp. Porous Med. 91 (2012) 423\u2013435.\r\n[4]\tW. Duangthongsuk, S. 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