Xiang Li and Kui Chen and Bin Wu and Min Zhou
Recycling of Sclareolide in the Crystallization Mother Liquid of Sclareolide by Adsorption and Chromatography
187 - 192
2016
10
2
International Journal of Chemical and Molecular Engineering
https://publications.waset.org/pdf/10003541
https://publications.waset.org/vol/110
World Academy of Science, Engineering and Technology
Sclareolide is made from sclareol by oxidiative synthesis and subsequent crystallization, while the crystallization mother liquor still contains 1530wt of sclareolide to be reclaimed. With the reaction material of sclareol is provided as plant extract, many sorts of complex impurities exist in the mother liquor. Due to the difficulty in recycling sclareolide after solvent recovery, it is common practice for the factories to discard the mother liquor, which not only results in loss of sclareolide, but also contributes extra environmental burden. In this paper, a process based on adsorption and elution has been presented for recycling of sclareolide from mother liquor. After pretreatment of the crystallization mother liquor by HZ845 resin to remove parts of impurities, sclareolide is adsorbed by HZ816 resin. The HZ816 resin loaded with sclareolide is then eluted by elution solvent. Finally, the eluent containing sclareolide is concentrated and fed into the crystallization step in the process. By adoption of the recycle from mother liquor, total yield of sclareolide increases from 86 to 90 with a stable purity of the final sclareolide products maintained.
Open Science Index 110, 2016