%0 Journal Article %A Young-Seok Choi %D 2015 %J International Journal of Biomedical and Biological Engineering %B World Academy of Science, Engineering and Technology %I Open Science Index 104, 2015 %T Correlated Neural Activity in Cortex and Thalamus Following Brain Injury %U https://publications.waset.org/pdf/10002605 %V 104 %X It has been known that a characteristic Burst-Suppression (BS) pattern appears in EEG during the early recovery period following Cardiac Arrest (CA). Here, to explore the relationship between cortical and subcortical neural activities underlying BS, extracellular activity in the parietal cortex and the centromedian nucleus of the thalamus and extradural EEG were recorded in a rodent CA model. During the BS, the cortical firing rate is extraordinarily high, and that bursts in EEG correlate to dense spikes in cortical neurons. Newly observed phenomena are that 1) thalamic activity reemerges earlier than cortical activity following CA, and 2) the correlation coefficient of cortical and thalamic activities rises during BS period. These results would help elucidate the underlying mechanism of brain recovery after CA injury. %P 656 - 659