%0 Journal Article
	%A Dmitriy Yu. Korulkin and  Raissa A. Muzychkina
	%D 2015
	%J International Journal of Bioengineering and Life Sciences
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 103, 2015
	%T Metabolites of Polygonum L. Plants Having Antitumor Properties
	%U https://publications.waset.org/pdf/10001456
	%V 103
	%X The article represents the results of research of
antitumor activity of different structural types of plant flavonoids
extracted by authors from Polygonum L. plants in commercial
reserves at the territory of the Republic of Kazakhstan. For the first
time ever the results comparative research of antitumor activity of
plant flavonoids of different structural groups and their synthetic
derivatives have been represented. The results of determination of
toxicity of flavonoids in single parenteral infusion conditions have
been represented. Experimental substantiation of possible
mechanisms of antiproliferative and cytotoxic action of flavonoids
has been suggested. The perspectives of usage of plant flavonoids as
medications and creation of effective dosage forms of antitumor
medicines on their basis have been substantiated.
	%P 705 - 708