%0 Journal Article
	%A Juliana A. Knocikova and  Yann Bouret and  Médéric Argentina and  Laurent Counillon
	%D 2014
	%J International Journal of Biomedical and Biological Engineering
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 92, 2014
	%T Mathematical Modeling of Cell Volume Alterations under Different Osmotic Conditions
	%U https://publications.waset.org/pdf/10000652
	%V 92
	%X Cell volume, together with membrane potential and
intracellular hydrogen ion concentration, is an essential biophysical
parameter for normal cellular activity. Cell volumes can be altered by
osmotically active compounds and extracellular tonicity.
In this study, a simple mathematical model of osmotically induced
cell swelling and shrinking is presented. Emphasis is given to water
diffusion across the membrane. The mathematical description of the
cellular behavior consists in a system of coupled ordinary differential
equations. We compare experimental data of cell volume alterations
driven by differences in osmotic pressure with mathematical
simulations under hypotonic and hypertonic conditions. Implications
for a future model are also discussed.

	%P 1164 - 1168