@article{(Open Science Index):https://publications.waset.org/pdf/10000422,
	  title     = {Anthocyanin Complex: Characterization and Cytotoxicity Studies},
	  author    = {Sucharat Limsitthichaikoon and  Kedsarin Saodaeng and  Aroonsri Priprem and  Teerasak Damrongrungruang},
	  country	= {},
	  institution	= {},
	  abstract     = {Complexation of anthocyanins to mimic natural
copigmentation process was investigated. Cyanidin-rich extracts from
Zea mays L. ceritina Kulesh. and delphinidin-rich extracts from
Clitoria ternatea L. were used to form 4 anthocyanin complexes,
AC1, AC2, AC3 and AC4, in the presence of several polyphenols and
a trace metal. Characterizations of the ACs were conducted by UV,
FTIR, DSC/TGA and morphological observations. Bathochromic
shifts of the UV spectra of 4 formulas of ACs were observed at peak
wavelengths of about 510-620 nm by 10 nm suggesting complex
formation. FTIR spectra of the ACs indicate shifts of peaks from
1,733 cm-1 to 1,696 cm-1 indicating interactions and a decrease in the
peak areas within the wavenumber of 3,400-3,500 cm-1 indicating
changes in hydrogen bonding. Thermal analysis of all of the ACs
suggests increases in melting temperature after complexation. AC
with the highest melting temperature was morphologically observed
by SEM and TEM to be crystal-like particles within a range of 50 to
200 nm. Particle size analysis of the AC by laser diffraction gave a
range of 50-600 nm, indicating aggregation. This AC was shown to
have no cytotoxic effect on cultured HGEPp0.5 and HGF (all p>
0.05) by MTT. Therefore, complexation of anthocyanins was simple
and self-assembly process, potentially resulting in nanosized particles
of anthocyanin complex.
	    journal   = {International Journal of Chemical and Molecular Engineering},
	  volume    = {9},
	  number    = {2},
	  year      = {2015},
	  pages     = {147 - 153},
	  ee        = {https://publications.waset.org/pdf/10000422},
	  url   	= {https://publications.waset.org/vol/98},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 98, 2015},