Salem El-t. Ashoor and Ibtisam M. Ediab
Synthesis, Investigation, DFT Study and Biological Activity of Zirconium (IV) Complexes
161 - 165
2014
8
2
International Journal of Chemical and Molecular Engineering
https://publications.waset.org/pdf/9998668
https://publications.waset.org/vol/86
World Academy of Science, Engineering and Technology
Zirconium diamine and triamine complexes can possess biological activities. These complexes were synthesised via the reaction of equimolar quantities of 1,10phenanthroline NC3H3(C6H2)NC3H3 (L1) or 44amino phenazone ONC6H5(NH)CH(NH2 (L2) or diphenyl carbizon HNNCO(NH)2(C6H5) (L3) with a Zirconium Salt ZrOCl2 in a 11 ratio to form complexes NC3H3(C6H2)NC3H3ZrOCl2 ZrOCl2L1, (O2NC6H4(NH)(NH2)ZrOCl2 ZrOCl2L2 and HNNCO(NH)2(C6H5)ZrOCl2 ZrOCl2L3 respectively. They were characterised using Fourier Transform Infrared (FTIR) and UVVisible spectroscopy. Also a variable temperature study of these complexes was completed, using UVVisible spectroscopy to observe electronic transitions under temperature control. Also a DFT study was done on these complexes via the information from FTIR and UVVisible spectroscopy.
These complexes were found to show different inhibition to the growth of bacterial strains of Bacillus spp. & Klebsiella spp. & E. coli & Proteus spp. & Pseudomona spp. at different concentrations (0.001, 0.2 and 1M). For better understanding these complexes were examined by using a Density Functional Theory (DFT) calculation.
Open Science Index 86, 2014